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Protein

Metal ABC transporter substrate-binding lipoprotein

Gene

scaA

Organism
Streptococcus gordonii
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Part of an ATP-driven transport system for a metal; probably for manganese. Also act as an adhesin which is involved on adherence to extracellular matrix. It is an important factor in pathogenesis and infection.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi68ZincBy similarity1
Metal bindingi140ZincBy similarity1
Metal bindingi206ZincBy similarity1
Metal bindingi281ZincBy similarity1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processTransport
LigandManganese, Metal-binding, Zinc

Protein family/group databases

TCDBi3.A.1.15.2. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Metal ABC transporter substrate-binding lipoprotein
Alternative name(s):
Coaggregation-mediating adhesin
Gene namesi
Name:scaA
OrganismiStreptococcus gordonii
Taxonomic identifieri1302 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliLactobacillalesStreptococcaceaeStreptococcus

Subcellular locationi

  • Cell membrane PROSITE-ProRule annotation; Lipid-anchor PROSITE-ProRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19CuratedAdd BLAST19
ChainiPRO_000003188620 – 310Metal ABC transporter substrate-binding lipoproteinAdd BLAST291

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi20N-palmitoyl cysteineCurated1
Lipidationi20S-diacylglycerol cysteineCurated1

Keywords - PTMi

Lipoprotein, Palmitate

Structurei

3D structure databases

ProteinModelPortaliP42364.
SMRiP42364.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4105DSE. Bacteria.
COG0803. LUCA.

Family and domain databases

InterProiView protein in InterPro
IPR006129. AdhesinB.
IPR006128. Lipoprotein_4.
IPR006127. ZnuA-like.
PfamiView protein in Pfam
PF01297. ZnuA. 1 hit.
PRINTSiPR00691. ADHESINB.
PR00690. ADHESNFAMILY.
PROSITEiView protein in PROSITE
PS51257. PROKAR_LIPOPROTEIN. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42364-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKCRFLVLL LLAFVGLAAC SSQKSSTDSS SSKLNVVATN SIIADITKNI
60 70 80 90 100
AGDKINLHSI VPVGQDPHKY EPLPEDVKKT SKADLIFYNG INLETGGNAW
110 120 130 140 150
FTKLVENAQK KENKDYYAVS EGVDVIYLEG QNEKGKEDPH AWLNLENGII
160 170 180 190 200
YAQNIAKRLI EKDPDNKATY EKNLKAYIEK LTALDKEAKE KFNNIPEEKK
210 220 230 240 250
MIVTSEGCPK YFSKAYNVPS AYIWEINTEE EGTPDQIKSL VEKLRKTKVP
260 270 280 290 300
SLFVESSVDD RPMKTVSKDT NIPIYAKIFT DSIAEKGEDG DSYYSMMKYN
310
LDKISEGLAK
Length:310
Mass (Da):34,788
Last modified:November 1, 1995 - v1
Checksum:iD1DEAB1A060BC252
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11577 Genomic DNA. Translation: AAA71947.1.
PIRiT11551.

Similar proteinsi

Entry informationi

Entry nameiMTSA_STRGN
AccessioniPrimary (citable) accession number: P42364
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 5, 2017
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program