P42349 (Y1242_SYNY3) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Uncharacterized methyltransferase sll1242
EC=2.1.1.-

Alternative name(s):
ORF N

Gene names

Ordered Locus Names:

sll1242

Organism

Synechocystis sp. (strain PCC 6803 / Kazusa) [Reference proteome] [HAMAP]

Taxonomic identifier

1111708 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Cyanobacteria › Oscillatoriophycideae › Chroococcales › Synechocystis › Synechocystis sp. PCC 6803

Protein attributes

Sequence length	536 AA.
Sequence status	Complete.
Protein existence	Predicted

General annotation (Comments)

Cofactor

Binds 1 4Fe-4S cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine Potential.

Ontologies

Keywords
Ligand	4Fe-4S Iron Iron-sulfur Metal-binding S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	4 iron, 4 sulfur cluster binding Inferred from electronic annotation. Source: UniProtKB-KW cobalamin binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW methyltransferase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 536	536	Uncharacterized methyltransferase sll1242		PRO_0000157884
Sites
	Metal binding	177	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	181	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential
	Metal binding	184	1	Iron-sulfur (4Fe-4S-S-AdoMet) Potential

Sequences

	Sequence		Length	Mass (Da)
	P42349 [UniParc]. Last modified May 30, 2000. Version 2. Checksum: 715F06F2C2D684E3	FASTA	536	61,756
	10 20 30 40 50 60 MRALLIYPLF PPTFWSYEKI LELVGRKVLL PPLGLITVAG ILPQEWEFKL VDRNVRNVTE 70 80 90 100 110 120 AEWDWAEVVI ISGMIVQRDD MVENIKEAKA HGKLVAVGGP FATSVPDEVQ NAGADFLILD 130 140 150 160 170 180 EGEITLPLFV EALERGETAG IIRAQEKPDV TTTPIPRYDL LELDAYDSMS VQFSRGCPFQ 190 200 210 220 230 240 CEFCDIIVLY GRKPRTKEPA QLLRELDYLY ELGWRRSVFM VDDNFIGNKR NVKLLLKELK 250 260 270 280 290 300 VWQEEHQYPF RFNTEASVDL ADDQELMDLM VECYFDAVFL GIETPDEESL EFTKKFQNTR 310 320 330 340 350 360 NSLADSVDKI IKAGLRPMAG FIIGFDGEKQ GAGDRIVRFA EQTAIPTTTF AMLQALPNTA 370 380 390 400 410 420 LWHRLKRENR LLDESKGNIN QTTLMNFIPT RPLEDIANEY VEAFWELYDP HGYLDRNYRC 430 440 450 460 470 480 FLKLGAPKCK TAFKLPNLVD LKALAIVIWR QGVKRDTRFR FWHHAFGILR HNPAVFEHYI 490 500 510 520 530 TLCAHNEHFL QYREIVRQEI GEQLRDYLSR QQQDKVEETV LSPTAIAAET EKVLAS

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of the genome of the unicellular cyanobacterium Synechocystis sp. strain PCC6803. II. Sequence determination of the entire genome and assignment of potential protein-coding regions." Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y., Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T., Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S. , Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S. DNA Res. 3:109-136(1996) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: PCC 6803 / Kazusa.
[2]	"Structure of a cyanobacterial gene encoding the 50S ribosomal protein L9." Malakhov M.P., Wada H., Los D.A., Sakamoto T., Murata N. Plant Mol. Biol. 21:913-918(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 291-536.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BA000022 Genomic DNA. Translation: BAA18175.1. D10716 Genomic DNA. Translation: BAA38817.1.
PIR	S75614.
RefSeq	NP_441495.1. NC_000911.1. YP_005651553.1. NC_017277.1. YP_007451377.1. NC_020286.1.
3D structure databases
ProteinModelPortal	P42349.
ModBase	Search...
Protein-protein interaction databases
STRING	1148.sll1242.
Proteomic databases
PaxDb	P42349.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	BAA18175; BAA18175; BAA18175.
GeneID	12254205. 14617037. 954875.
KEGG	syn:sll1242. syy:SYNGTS_1600.
PATRIC	23840407. VBISynSp132158_1761.
Phylogenomic databases
eggNOG	COG1032.
OMA	IRVMAGF.
ProtClustDB	CLSK893148.
Family and domain databases
Gene3D	3.80.30.20. 1 hit.
InterPro	IPR006158. Cobalamin-bd. IPR025274. DUF4070. IPR006638. Elp3/MiaB/NifB. IPR023970. MeThioTfrase/rSAM. IPR007197. rSAM. IPR023404. rSAM_horseshoe. [Graphical view]
PANTHER	PTHR11918. PTHR11918. 1 hit.
Pfam	PF02310. B12-binding. 1 hit. PF13282. DUF4070. 1 hit. PF04055. Radical_SAM. 1 hit. [Graphical view]
SMART	SM00729. Elp3. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Y1242_SYNY3

Accession

Primary (citable) accession number: P42349

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	May 30, 2000
Last modified:	May 1, 2013
This is version 80 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program