SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P42348

- PI3K2_SOYBN

UniProt

P42348 - PI3K2_SOYBN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphatidylinositol 3-kinase, nodule isoform

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Associated with membrane proliferation.

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.

GO - Molecular functioni

  1. 1-phosphatidylinositol-3-kinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. endocytosis Source: EnsemblPlants/Gramene
  2. microgametogenesis Source: EnsemblPlants/Gramene
  3. phosphatidylinositol-mediated signaling Source: InterPro
  4. reactive oxygen species metabolic process Source: EnsemblPlants/Gramene
  5. response to salt stress Source: EnsemblPlants/Gramene
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.1.137. 2483.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 3-kinase, nodule isoform (EC:2.7.1.137)
Short name:
PI3-kinase
Short name:
PI3K
Short name:
PtdIns-3-kinase
Alternative name(s):
SPI3K-1
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 812812Phosphatidylinositol 3-kinase, nodule isoformPRO_0000088821Add
BLAST

Expressioni

Inductioni

Highly expressed in young root nodules in parallel with membrane proliferation but is repressed in mature nodules.

Gene expression databases

GenevestigatoriP42348.

Structurei

3D structure databases

ProteinModelPortaliP42348.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 175162C2 PI3K-typeAdd
BLAST
Domaini272 – 447176PIK helicalAdd
BLAST
Domaini560 – 812253PI3K/PI4KAdd
BLAST

Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.
Contains 1 PI3K/PI4K domain.
Contains 1 PIK helical domain.

Phylogenomic databases

KOiK00914.

Family and domain databases

Gene3Di1.10.1070.11. 1 hit.
1.25.40.70. 1 hit.
2.60.40.150. 2 hits.
InterProiIPR016024. ARM-type_fold.
IPR000008. C2_dom.
IPR011009. Kinase-like_dom.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2_dom.
IPR008290. PI3K_Vps34.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view]
PIRSFiPIRSF000587. PI3K_Vps34. 1 hit.
SMARTiSM00142. PI3K_C2. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF54452. SSF54452. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
PS51547. PI3K_C2. 1 hit.
PS51545. PIK_HELICAL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42348-1 [UniParc]FASTAAdd to Basket

« Hide

MTGNEFRFFL SCDISVPVTF RVERLEGNLP LPKSPDLENN APTDNRTTEL    50
FVECALYIDG APFGLPMRTR LESLGPSYCW NELITLTTKY RDLTAQSQLT 100
FTVWDLSHGE GLIGGATILL FNNKKQLKTG KQKLRLWAGK EADGTFPTST 150
PGKVPRHERG ELERLEKLVN KYERGQIQRV DWLDRLTFKT MERIKERESL 200
KNGSSHMYLV VDFCSFEHRV VFQESGANFL FPSPIASTND IVVVWDPEVG 250
KINPSEHKQL KLARSLTRGV IDRDLKPSSN ERKSIQRILK YPPTRTLSGD 300
ERQLLWKFRF SLMSEKRALT KFLRCVEWSD VQEAKQALEL MGKWEMIDVC 350
DALELLSPVF ESEEVRAYAV SVLERADDEE LQCYLLQLVQ ALRFERSAKS 400
RLSHFLIQCA LRNIELASFL RWYVAVELYD PAYAKRFYCT YEILEENMMK 450
IAAGVNGEED GFKQWQSLVR QTELTAQLCS ITREVSNVRG NTQKKIEKLR 500
QLLSGLLSEL TYFDEPIRSP LAPGVLITGI VPSESSIFKS ALHPLRLTFR 550
AANGGTCKII FKKGDDIRQD QLVVQMVSLM DRLLKLENLD LHLTPYKVLA 600
TGQDEGMLEF IPSRSLAQIL SENRSIISYL QKFHPDDHGP FGITATCLET 650
FIKSCAGYSV ITYILGIGDR HLDNLLLRND GGLFHVDFGF ILGRDPKPFP 700
PPMKLCKEMV EAMGGAESQY YTRFKSYCCE AYHILRKSSN LILNLFYLMA 750
GSNIPDIASD PEKGILKLQE KFRLDLDDEA SIHFFQDLIN ESVSALFPQM 800
VETIHRWAQY WR 812
Length:812
Mass (Da):93,002
Last modified:November 1, 1995 - v1
Checksum:i94C5A922AF198A4B
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L29770 mRNA. Translation: AAA64468.1.
PIRiT07745.
RefSeqiNP_001242315.1. NM_001255386.1.
UniGeneiGma.64312.

Genome annotation databases

GeneIDi100778348.
KEGGigmx:100778348.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L29770 mRNA. Translation: AAA64468.1 .
PIRi T07745.
RefSeqi NP_001242315.1. NM_001255386.1.
UniGenei Gma.64312.

3D structure databases

ProteinModelPortali P42348.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 100778348.
KEGGi gmx:100778348.

Phylogenomic databases

KOi K00914.

Enzyme and pathway databases

BRENDAi 2.7.1.137. 2483.

Gene expression databases

Genevestigatori P42348.

Family and domain databases

Gene3Di 1.10.1070.11. 1 hit.
1.25.40.70. 1 hit.
2.60.40.150. 2 hits.
InterProi IPR016024. ARM-type_fold.
IPR000008. C2_dom.
IPR011009. Kinase-like_dom.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2_dom.
IPR008290. PI3K_Vps34.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view ]
PANTHERi PTHR10048. PTHR10048. 1 hit.
Pfami PF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view ]
PIRSFi PIRSF000587. PI3K_Vps34. 1 hit.
SMARTi SM00142. PI3K_C2. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF54452. SSF54452. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
PS51547. PI3K_C2. 1 hit.
PS51545. PIK_HELICAL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A phosphatidylinositol 3-kinase is induced during soybean nodule organogenesis and is associated with membrane proliferation."
    Hong Z., Verma D.P.S.
    Proc. Natl. Acad. Sci. U.S.A. 91:9617-9621(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Prize.
    Tissue: Root nodule.

Entry informationi

Entry nameiPI3K2_SOYBN
AccessioniPrimary (citable) accession number: P42348
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 3, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi