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P42348 (PI3K2_SOYBN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 91. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphatidylinositol 3-kinase, nodule isoform

Short name=PI3-kinase
Short name=PI3K
Short name=PtdIns-3-kinase
EC=2.7.1.137
Alternative name(s):
SPI3K-1
OrganismGlycine max (Soybean) (Glycine hispida) [Reference proteome]
Taxonomic identifier3847 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja

Protein attributes

Sequence length812 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Associated with membrane proliferation.

Catalytic activity

ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.

Induction

Highly expressed in young root nodules in parallel with membrane proliferation but is repressed in mature nodules.

Sequence similarities

Belongs to the PI3/PI4-kinase family.

Contains 1 C2 PI3K-type domain.

Contains 1 PI3K/PI4K domain.

Contains 1 PIK helical domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 812812Phosphatidylinositol 3-kinase, nodule isoform
PRO_0000088821

Regions

Domain14 – 175162C2 PI3K-type
Domain272 – 447176PIK helical
Domain560 – 812253PI3K/PI4K

Sequences

Sequence LengthMass (Da)Tools
P42348 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 94C5A922AF198A4B

FASTA81293,002
        10         20         30         40         50         60 
MTGNEFRFFL SCDISVPVTF RVERLEGNLP LPKSPDLENN APTDNRTTEL FVECALYIDG 

        70         80         90        100        110        120 
APFGLPMRTR LESLGPSYCW NELITLTTKY RDLTAQSQLT FTVWDLSHGE GLIGGATILL 

       130        140        150        160        170        180 
FNNKKQLKTG KQKLRLWAGK EADGTFPTST PGKVPRHERG ELERLEKLVN KYERGQIQRV 

       190        200        210        220        230        240 
DWLDRLTFKT MERIKERESL KNGSSHMYLV VDFCSFEHRV VFQESGANFL FPSPIASTND 

       250        260        270        280        290        300 
IVVVWDPEVG KINPSEHKQL KLARSLTRGV IDRDLKPSSN ERKSIQRILK YPPTRTLSGD 

       310        320        330        340        350        360 
ERQLLWKFRF SLMSEKRALT KFLRCVEWSD VQEAKQALEL MGKWEMIDVC DALELLSPVF 

       370        380        390        400        410        420 
ESEEVRAYAV SVLERADDEE LQCYLLQLVQ ALRFERSAKS RLSHFLIQCA LRNIELASFL 

       430        440        450        460        470        480 
RWYVAVELYD PAYAKRFYCT YEILEENMMK IAAGVNGEED GFKQWQSLVR QTELTAQLCS 

       490        500        510        520        530        540 
ITREVSNVRG NTQKKIEKLR QLLSGLLSEL TYFDEPIRSP LAPGVLITGI VPSESSIFKS 

       550        560        570        580        590        600 
ALHPLRLTFR AANGGTCKII FKKGDDIRQD QLVVQMVSLM DRLLKLENLD LHLTPYKVLA 

       610        620        630        640        650        660 
TGQDEGMLEF IPSRSLAQIL SENRSIISYL QKFHPDDHGP FGITATCLET FIKSCAGYSV 

       670        680        690        700        710        720 
ITYILGIGDR HLDNLLLRND GGLFHVDFGF ILGRDPKPFP PPMKLCKEMV EAMGGAESQY 

       730        740        750        760        770        780 
YTRFKSYCCE AYHILRKSSN LILNLFYLMA GSNIPDIASD PEKGILKLQE KFRLDLDDEA 

       790        800        810 
SIHFFQDLIN ESVSALFPQM VETIHRWAQY WR 

« Hide

References

[1]"A phosphatidylinositol 3-kinase is induced during soybean nodule organogenesis and is associated with membrane proliferation."
Hong Z., Verma D.P.S.
Proc. Natl. Acad. Sci. U.S.A. 91:9617-9621(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Prize.
Tissue: Root nodule.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L29770 mRNA. Translation: AAA64468.1.
PIRT07745.
RefSeqNP_001242315.1. NM_001255386.1.
UniGeneGma.64312.

3D structure databases

ProteinModelPortalP42348.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID100778348.
KEGGgmx:100778348.

Enzyme and pathway databases

BRENDA2.7.1.137. 2483.

Gene expression databases

GenevestigatorP42348.

Family and domain databases

Gene3D1.10.1070.11. 1 hit.
1.25.40.70. 1 hit.
2.60.40.150. 2 hits.
InterProIPR016024. ARM-type_fold.
IPR000008. C2_dom.
IPR011009. Kinase-like_dom.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2_dom.
IPR008290. PI3K_Vps34.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view]
PANTHERPTHR10048. PTHR10048. 1 hit.
PfamPF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view]
PIRSFPIRSF000587. PI3K_Vps34. 1 hit.
SMARTSM00142. PI3K_C2. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view]
SUPFAMSSF48371. SSF48371. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF54452. SSF54452. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
PS51547. PI3K_C2. 1 hit.
PS51545. PIK_HELICAL. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePI3K2_SOYBN
AccessionPrimary (citable) accession number: P42348
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families