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P42347

- PI3K1_SOYBN

UniProt

P42347 - PI3K1_SOYBN

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Protein

Phosphatidylinositol 3-kinase, root isoform

Gene
N/A
Organism
Glycine max (Soybean) (Glycine hispida)
Status
Reviewed - Annotation score: 3 out of 5 - Experimental evidence at transcript leveli

Functioni

Associated with membrane proliferation.

Catalytic activityi

ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo-inositol 3-phosphate.

GO - Molecular functioni

  1. 1-phosphatidylinositol-3-kinase activity Source: UniProtKB-EC
  2. ATP binding Source: UniProtKB-KW

GO - Biological processi

  1. phosphatidylinositol-mediated signaling Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BRENDAi2.7.1.137. 2483.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphatidylinositol 3-kinase, root isoform (EC:2.7.1.137)
Short name:
PI3-kinase
Short name:
PI3K
Short name:
PtdIns-3-kinase
Alternative name(s):
SPI3K-5
OrganismiGlycine max (Soybean) (Glycine hispida)
Taxonomic identifieri3847 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsfabidsFabalesFabaceaePapilionoideaePhaseoleaeGlycineSoja
ProteomesiUP000008827: Unplaced

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 814814Phosphatidylinositol 3-kinase, root isoformPRO_0000088820Add
BLAST

Expressioni

Inductioni

Repressed during nodule organogenesis and reinduced in mature nodules.

Gene expression databases

GenevestigatoriP42347.

Structurei

3D structure databases

ProteinModelPortaliP42347.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 177164C2 PI3K-typeAdd
BLAST
Domaini274 – 449176PIK helicalAdd
BLAST
Domaini558 – 811254PI3K/PI4KAdd
BLAST

Sequence similaritiesi

Belongs to the PI3/PI4-kinase family.
Contains 1 PI3K/PI4K domain.
Contains 1 PIK helical domain.

Phylogenomic databases

KOiK00914.

Family and domain databases

Gene3Di1.10.1070.11. 1 hit.
1.25.40.70. 1 hit.
2.60.40.150. 2 hits.
InterProiIPR016024. ARM-type_fold.
IPR000008. C2_dom.
IPR011009. Kinase-like_dom.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2_dom.
IPR008290. PI3K_Vps34.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view]
PANTHERiPTHR10048. PTHR10048. 1 hit.
PfamiPF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view]
PIRSFiPIRSF000587. PI3K_Vps34. 1 hit.
SMARTiSM00239. C2. 1 hit.
SM00142. PI3K_C2. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view]
SUPFAMiSSF48371. SSF48371. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF54452. SSF54452. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEiPS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
PS51547. PI3K_C2. 1 hit.
PS51545. PIK_HELICAL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42347-1 [UniParc]FASTAAdd to Basket

« Hide

MTGNEFRFFL SCDISVPVTF RVERLEGNLP LPNPKSPDLE TNAPTENRTK    50
ELFVECALYI DGAPFGLPTR TRLESSGPSY CWNELITLTT KYRDLTAQSQ 100
LTFTVWDLSH GEGLIGGATI LLFNNKKQLK TGKQKLRLWA GKEADGTFPT 150
STPGKVPRHE RGELERLEKL VNKYERGQIQ RVDWLDRLTF KTMERIKERE 200
SLKNGSSHLY LVVDFCSFEH RVVFQESGAN FLFPSPIAST NDIVVVWDPE 250
VGKINPSEHK QLKLARSLTR GVIDRDLKPS SNERKSIQRI LKYPPTRTLS 300
GDERQLLWKF RFSLMSEKRA LTKFLRCVEW SDVQEAKQAL ELMGKWEMID 350
VCDALELLSP VFESEEVRAY AVSVLERADD EELQCYLLQL VQALRFERSD 400
KSRLSHFLVQ RALRNIELAS FLRWYVAVEL YDPAYAKRFY CTYEILEENM 450
MKIAAGVNGE EDGFKQWQSL VRQTELTAQL CSITREVRNV RGNTQKKIEK 500
LRQLLSGLLS ELTYFDEPIR SPLAPGVLIA GIVPSESSIF KSALHPLRLS 550
FRTANGGTCK IIFKKGDDLR QDQLVVQMVS LMDRLLKLEN LDLHLTPYKV 600
LATGQDEGML EFIPSRSLAQ ILSENRSIIS YLQKFHPDDH GPFGITATCL 650
ETFIKSCAGY SVITYILGIG DRHLDNLLLR NDGGLFHVDF GFILGRDPKP 700
FPPPMKLCKE MVEAMGGAES QYYTRFKSYC CEAYNILRKS SNLILNLFYL 750
MAGSNIPDIA SDPEKGILKL QEKFRLDLDD EASIHFFQDL INESVSALFP 800
QMVETIHRWA QYWR 814
Length:814
Mass (Da):93,282
Last modified:November 1, 1995 - v1
Checksum:i5B13A7DE16FFA0AD
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27265 mRNA. Translation: AAA83995.1.
PIRiT07761.
RefSeqiNP_001236955.1. NM_001250026.2.
UniGeneiGma.2544.

Genome annotation databases

GeneIDi547983.
KEGGigmx:547983.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L27265 mRNA. Translation: AAA83995.1 .
PIRi T07761.
RefSeqi NP_001236955.1. NM_001250026.2.
UniGenei Gma.2544.

3D structure databases

ProteinModelPortali P42347.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 547983.
KEGGi gmx:547983.

Phylogenomic databases

KOi K00914.

Enzyme and pathway databases

BRENDAi 2.7.1.137. 2483.

Gene expression databases

Genevestigatori P42347.

Family and domain databases

Gene3Di 1.10.1070.11. 1 hit.
1.25.40.70. 1 hit.
2.60.40.150. 2 hits.
InterProi IPR016024. ARM-type_fold.
IPR000008. C2_dom.
IPR011009. Kinase-like_dom.
IPR011162. MHC_I/II-like_Ag-recog.
IPR000403. PI3/4_kinase_cat_dom.
IPR018936. PI3/4_kinase_CS.
IPR002420. PI3K_C2_dom.
IPR008290. PI3K_Vps34.
IPR015433. PI_Kinase.
IPR001263. PInositide-3_kin_accessory_dom.
[Graphical view ]
PANTHERi PTHR10048. PTHR10048. 1 hit.
Pfami PF00454. PI3_PI4_kinase. 1 hit.
PF00792. PI3K_C2. 1 hit.
PF00613. PI3Ka. 1 hit.
[Graphical view ]
PIRSFi PIRSF000587. PI3K_Vps34. 1 hit.
SMARTi SM00239. C2. 1 hit.
SM00142. PI3K_C2. 1 hit.
SM00145. PI3Ka. 1 hit.
SM00146. PI3Kc. 1 hit.
[Graphical view ]
SUPFAMi SSF48371. SSF48371. 1 hit.
SSF49562. SSF49562. 1 hit.
SSF54452. SSF54452. 1 hit.
SSF56112. SSF56112. 1 hit.
PROSITEi PS00915. PI3_4_KINASE_1. 1 hit.
PS00916. PI3_4_KINASE_2. 1 hit.
PS50290. PI3_4_KINASE_3. 1 hit.
PS51547. PI3K_C2. 1 hit.
PS51545. PIK_HELICAL. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "A phosphatidylinositol 3-kinase is induced during soybean nodule organogenesis and is associated with membrane proliferation."
    Hong Z., Verma D.P.S.
    Proc. Natl. Acad. Sci. U.S.A. 91:9617-9621(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Prize.
    Tissue: Root.

Entry informationi

Entry nameiPI3K1_SOYBN
AccessioniPrimary (citable) accession number: P42347
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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