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Protein

Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A

Gene

scoA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Succinyl-CoA + a 3-oxo acid = succinate + a 3-oxoacyl-CoA.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Transferase

Enzyme and pathway databases

BioCyciBSUB:BSU38990-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit A (EC:2.8.3.5)
Alternative name(s):
Succinyl-CoA:3-oxoacid CoA-transferase
Short name:
OXCT A
Gene namesi
Name:scoA
Synonyms:yxjD
Ordered Locus Names:BSU38990
ORF Names:N15K
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 238238Probable succinyl-CoA:3-ketoacid coenzyme A transferase subunit APRO_0000157908Add
BLAST

Proteomic databases

PaxDbiP42315.

Interactioni

Subunit structurei

Heterodimer of a subunit A and a subunit B.By similarity

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021041.

Structurei

Secondary structure

1
238
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Helixi8 – 125Combined sources
Beta strandi20 – 234Combined sources
Helixi33 – 4210Combined sources
Beta strandi46 – 538Combined sources
Beta strandi57 – 593Combined sources
Helixi62 – 665Combined sources
Beta strandi70 – 778Combined sources
Helixi82 – 887Combined sources
Turni89 – 913Combined sources
Beta strandi92 – 976Combined sources
Helixi100 – 11213Combined sources
Beta strandi116 – 1205Combined sources
Turni121 – 1244Combined sources
Helixi126 – 1283Combined sources
Beta strandi133 – 1364Combined sources
Beta strandi139 – 1457Combined sources
Beta strandi149 – 16012Combined sources
Helixi169 – 1713Combined sources
Helixi175 – 1817Combined sources
Beta strandi182 – 19312Combined sources
Turni200 – 2023Combined sources
Helixi207 – 2093Combined sources
Beta strandi211 – 2155Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3CDKX-ray2.59A/C1-238[»]
ProteinModelPortaliP42315.
SMRiP42315. Positions 1-229.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP42315.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 307CoA-bindingSequence analysis

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105D6N. Bacteria.
COG1788. LUCA.
HOGENOMiHOG000221244.
InParanoidiP42315.
KOiK01028.
OMAiGWKADWY.
OrthoDBiEOG6HMXJG.
PhylomeDBiP42315.

Family and domain databases

InterProiIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEiPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42315-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGKVLSSSKE AAKLIHDGDT LIAGGFGLCG IPEQLILSIR DQGVKDLTVV
60 70 80 90 100
SNNCGVDDWG LGLLLANKQI KKMIASYVGE NKIFERQFLS GELEVELVPQ
110 120 130 140 150
GTLAERIRAG GAGIPGFYTA TGVGTSIAEG KEHKTFGGRT YVLERGITGD
160 170 180 190 200
VAIVKAWKAD TMGNLIFRKT ARNFNPIAAM AGKITIAEAE EIVEAGELDP
210 220 230
DHIHTPGIYV QHVVLGASQE KRIEKRTVQQ ASGKGEAK
Length:238
Mass (Da):25,399
Last modified:November 1, 1995 - v1
Checksum:iE88552A437098CE0
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83026 Genomic DNA. Translation: BAA11705.1.
AL009126 Genomic DNA. Translation: CAB15925.1.
PIRiB70079.
RefSeqiNP_391778.1. NC_000964.3.
WP_003244373.1. NZ_JNCM01000034.1.

Genome annotation databases

EnsemblBacteriaiCAB15925; CAB15925; BSU38990.
GeneIDi937468.
KEGGibsu:BSU38990.
PATRICi18979848. VBIBacSub10457_4086.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83026 Genomic DNA. Translation: BAA11705.1.
AL009126 Genomic DNA. Translation: CAB15925.1.
PIRiB70079.
RefSeqiNP_391778.1. NC_000964.3.
WP_003244373.1. NZ_JNCM01000034.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3CDKX-ray2.59A/C1-238[»]
ProteinModelPortaliP42315.
SMRiP42315. Positions 1-229.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021041.

Proteomic databases

PaxDbiP42315.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15925; CAB15925; BSU38990.
GeneIDi937468.
KEGGibsu:BSU38990.
PATRICi18979848. VBIBacSub10457_4086.

Phylogenomic databases

eggNOGiENOG4105D6N. Bacteria.
COG1788. LUCA.
HOGENOMiHOG000221244.
InParanoidiP42315.
KOiK01028.
OMAiGWKADWY.
OrthoDBiEOG6HMXJG.
PhylomeDBiP42315.

Enzyme and pathway databases

BioCyciBSUB:BSU38990-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP42315.

Family and domain databases

InterProiIPR012792. 3-oxoacid_CoA-transf_A.
IPR004165. CoA_trans_fam_I.
IPR004163. CoA_transf_BS.
[Graphical view]
PANTHERiPTHR13707. PTHR13707. 1 hit.
PfamiPF01144. CoA_trans. 1 hit.
[Graphical view]
SMARTiSM00882. CoA_trans. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02429. pcaI_scoA_fam. 1 hit.
PROSITEiPS01273. COA_TRANSF_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region."
    Yoshida K., Shindo K., Sano H., Seki S., Fujimura M., Yanai N., Miwa Y., Fujita Y.
    Microbiology 142:3113-3123(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / BGSC1A1.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.

Entry informationi

Entry nameiSCOA_BACSU
AccessioniPrimary (citable) accession number: P42315
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: July 6, 2016
This is version 110 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.