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Protein

Uncharacterized esterase YxiM

Gene

yxiM

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei186 – 1861NucleophileBy similarity
Active sitei354 – 3541By similarity
Active sitei357 – 3571By similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

BioCyciBSUB:BSU39120-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Uncharacterized esterase YxiM (EC:3.1.-.-)
Gene namesi
Name:yxiM
Ordered Locus Names:BSU39120
ORF Names:SS8D
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 382357Uncharacterized esterase YxiMPRO_0000013744Add
BLAST

Proteomic databases

PaxDbiP42304.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021116.

Structurei

Secondary structure

1
382
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi30 – 389Combined sources
Beta strandi44 – 474Combined sources
Turni55 – 573Combined sources
Beta strandi58 – 625Combined sources
Helixi64 – 663Combined sources
Beta strandi67 – 715Combined sources
Beta strandi73 – 753Combined sources
Helixi76 – 794Combined sources
Beta strandi80 – 867Combined sources
Beta strandi95 – 984Combined sources
Beta strandi101 – 11212Combined sources
Beta strandi114 – 1207Combined sources
Beta strandi123 – 1319Combined sources
Beta strandi135 – 1428Combined sources
Beta strandi144 – 15512Combined sources
Beta strandi161 – 17313Combined sources
Beta strandi179 – 1846Combined sources
Turni186 – 1883Combined sources
Turni194 – 1963Combined sources
Helixi202 – 2054Combined sources
Helixi206 – 2083Combined sources
Turni212 – 2143Combined sources
Beta strandi216 – 2194Combined sources
Helixi227 – 2326Combined sources
Helixi235 – 2406Combined sources
Beta strandi248 – 2525Combined sources
Helixi256 – 2583Combined sources
Helixi260 – 2623Combined sources
Helixi266 – 28116Combined sources
Turni282 – 2843Combined sources
Beta strandi286 – 2905Combined sources
Helixi313 – 32210Combined sources
Beta strandi326 – 3283Combined sources
Helixi330 – 34112Combined sources
Helixi343 – 3475Combined sources
Beta strandi355 – 3595Combined sources
Helixi360 – 37617Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2O14X-ray2.10A17-382[»]
ProteinModelPortaliP42304.
SMRiP42304. Positions 29-382.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP42304.

Family & Domainsi

Sequence similaritiesi

Belongs to the 'GDSL' lipolytic enzyme family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG4107TDE. Bacteria.
COG2755. LUCA.
COG3401. LUCA.
HOGENOMiHOG000087899.
InParanoidiP42304.
OMAiLGINDTN.
OrthoDBiEOG689HPV.
PhylomeDBiP42304.

Family and domain databases

Gene3Di3.40.50.1110. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR013830. SGNH_hydro.
[Graphical view]
PfamiPF13472. Lipase_GDSL_2. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52266. SSF52266. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42304-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKWMAAVFV MMLMLCFGGI ENVKAAEPKV YQFDFGSGSM EPGYIGVRAS
60 70 80 90 100
DRYDRSKGYG FQTPENMRDV AASGAGVKSD AVQFLAYGTK SNNTFNVDLP
110 120 130 140 150
NGLYEVKVTL GNTARASVAA EGVFQVINMT GDGAEDTFQI PVTDGQLNLL
160 170 180 190 200
VTEGKAGTAF TLSALKIKKL SDQPVTNRTI YVGGDSTVCN YYPLNSSKQA
210 220 230 240 250
GWGQMLPHYI DKHTFQVRNM ASGGQIARGF RNDGQLEAIL KYIKPGDYFM
260 270 280 290 300
LQLGINDTNP KHKESEAEFK EVMRDMIRQV KAKGADVILS TPQGRATDFT
310 320 330 340 350
SEGIHSSVNR WYRASILALA EEEKTYLIDL NVLSSAYFTS IGPERTLGLY
360 370 380
MDGDTLHPNR AGADALARLA VQELKRQGIA GF
Length:382
Mass (Da):41,836
Last modified:July 28, 2009 - v2
Checksum:iB46ADC4054B3C97D
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti83 – 831Q → E in BAA11692 (PubMed:8969509).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83026 Genomic DNA. Translation: BAA11692.1.
AL009126 Genomic DNA. Translation: CAB15948.2.
PIRiA70078.
RefSeqiNP_391791.2. NC_000964.3.
WP_003242617.1. NZ_JNCM01000034.1.

Genome annotation databases

EnsemblBacteriaiCAB15948; CAB15948; BSU39120.
GeneIDi937485.
KEGGibsu:BSU39120.
PATRICi18979886. VBIBacSub10457_4105.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D83026 Genomic DNA. Translation: BAA11692.1.
AL009126 Genomic DNA. Translation: CAB15948.2.
PIRiA70078.
RefSeqiNP_391791.2. NC_000964.3.
WP_003242617.1. NZ_JNCM01000034.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2O14X-ray2.10A17-382[»]
ProteinModelPortaliP42304.
SMRiP42304. Positions 29-382.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100021116.

Proteomic databases

PaxDbiP42304.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB15948; CAB15948; BSU39120.
GeneIDi937485.
KEGGibsu:BSU39120.
PATRICi18979886. VBIBacSub10457_4105.

Phylogenomic databases

eggNOGiENOG4107TDE. Bacteria.
COG2755. LUCA.
COG3401. LUCA.
HOGENOMiHOG000087899.
InParanoidiP42304.
OMAiLGINDTN.
OrthoDBiEOG689HPV.
PhylomeDBiP42304.

Enzyme and pathway databases

BioCyciBSUB:BSU39120-MONOMER.

Miscellaneous databases

EvolutionaryTraceiP42304.

Family and domain databases

Gene3Di3.40.50.1110. 1 hit.
InterProiIPR008979. Galactose-bd-like.
IPR013830. SGNH_hydro.
[Graphical view]
PfamiPF13472. Lipase_GDSL_2. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 1 hit.
SSF52266. SSF52266. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Sequencing of a 65 kb region of the Bacillus subtilis genome containing the lic and cel loci, and creation of a 177 kb contig covering the gnt-sacXY region."
    Yoshida K., Shindo K., Sano H., Seki S., Fujimura M., Yanai N., Miwa Y., Fujita Y.
    Microbiology 142:3113-3123(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: 168 / BGSC1A1.
  2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
    Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
    , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
    Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 168.
  3. "From a consortium sequence to a unified sequence: the Bacillus subtilis 168 reference genome a decade later."
    Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A., Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.
    Microbiology 155:1758-1775(2009) [PubMed] [Europe PMC] [Abstract]
    Cited for: SEQUENCE REVISION TO 83.
  4. "X-ray structure of the hypothetical protein YXIM_BACSU from Bacillus subtilis."
    Northeast structural genomics consortium (NESG)
    Submitted (DEC-2006) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS) OF 17-382.

Entry informationi

Entry nameiYXIM_BACSU
AccessioniPrimary (citable) accession number: P42304
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: July 28, 2009
Last modified: February 17, 2016
This is version 105 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.