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P42270

- HPCG_ECOLX

UniProt

P42270 - HPCG_ECOLX

Protein

2-oxo-hepta-3-ene-1,7-dioic acid hydratase

Gene

hpcG

Organism
Escherichia coli
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 56 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Transforms 2-oxo-hept-3-ene-1,7-dioate (OHED) into 2,4-dihydroxy-hept-2-ene-1,7-dioic acid (HHED).

    Pathwayi

    GO - Molecular functioni

    1. lyase activity Source: UniProtKB-KW

    GO - Biological processi

    1. aromatic compound catabolic process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Aromatic hydrocarbons catabolism

    Enzyme and pathway databases

    BioCyciRETL1328306-WGS:GSTH-2308-MONOMER.
    UniPathwayiUPA00208; UER00421.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    2-oxo-hepta-3-ene-1,7-dioic acid hydratase (EC:4.2.-.-)
    Short name:
    OHED hydratase
    Gene namesi
    Name:hpcG
    OrganismiEscherichia coli
    Taxonomic identifieri562 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 2642642-oxo-hepta-3-ene-1,7-dioic acid hydratasePRO_0000084042Add
    BLAST

    Proteomic databases

    PRIDEiP42270.

    Structurei

    3D structure databases

    ProteinModelPortaliP42270.
    SMRiP42270. Positions 1-264.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the hydratase/decarboxylase family.Curated

    Family and domain databases

    Gene3Di3.90.850.10. 1 hit.
    InterProiIPR002529. Fumarylacetoacetase_C.
    IPR011234. Fumarylacetoacetase_C-rel.
    IPR012690. HpaH.
    [Graphical view]
    PfamiPF01557. FAA_hydrolase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56529. SSF56529. 1 hit.
    TIGRFAMsiTIGR02312. HpaH. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    P42270-1 [UniParc]FASTAAdd to Basket

    « Hide

    MFDKHTHTLI AQRLDQAEKQ REQIRAISLD YPEITIEDAY AVQREWVRLK    50
    IAEGRTLKGH KIGLTSKAMQ ASSQISEPDY GALLHDNVLP RWQRYRFIVP 100
    RIEVELAFVL AKPLRGPNCT LFDVYNATDY VIPALELIDA RCHNIDPETQ 150
    RPRKVFDTIS DNAANSGVIL GGRPIKPDEL DLRWISALMY RNGVIEETGV 200
    AAGVLNHPAN GVAWLANKLA PYDVQLEAGQ IILGGSFTRP VPARKGDTFH 250
    VDYGNMGSIS CRFV 264
    Length:264
    Mass (Da):29,603
    Last modified:November 1, 1995 - v1
    Checksum:iE1D7CFF9F872751C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X81446 Genomic DNA. Translation: CAA57202.1.
    PIRiI41083.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X81446 Genomic DNA. Translation: CAA57202.1 .
    PIRi I41083.

    3D structure databases

    ProteinModelPortali P42270.
    SMRi P42270. Positions 1-264.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P42270.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00208 ; UER00421 .
    BioCyci RETL1328306-WGS:GSTH-2308-MONOMER.

    Family and domain databases

    Gene3Di 3.90.850.10. 1 hit.
    InterProi IPR002529. Fumarylacetoacetase_C.
    IPR011234. Fumarylacetoacetase_C-rel.
    IPR012690. HpaH.
    [Graphical view ]
    Pfami PF01557. FAA_hydrolase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56529. SSF56529. 1 hit.
    TIGRFAMsi TIGR02312. HpaH. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Sequence of the hpcC and hpcG genes of the meta-fission homoprotocatechuic acid pathway of Escherichia coli C: nearly 40% amino-acid identity with the analogous enzymes of the catechol pathway."
      Roper D.I., Stringfellow J.M., Cooper R.A.
      Gene 156:47-51(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: C.

    Entry informationi

    Entry nameiHPCG_ECOLX
    AccessioniPrimary (citable) accession number: P42270
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 56 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3