P42256 (ABNA_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Arabinan endo-1,5-alpha-L-arabinosidase A
EC=3.2.1.99

Alternative name(s):
Endo-1,5-alpha-L-arabinanase A
Short name=ABN A

Gene names

Name:

abnA

Organism

Aspergillus niger

Taxonomic identifier

5061 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Opisthokonta › Fungi › Dikarya › Ascomycota › saccharomyceta › Pezizomycotina › leotiomyceta › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	321 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level

General annotation (Comments)

Function	Its preferred substrate is linear 1,5-alpha-L-arabinan. The enzyme activity is progressively reduced as 1,5-alpha-chains become shorter or more highly substituted.
Catalytic activity	Endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5)-arabinans.
Pathway	Glycan metabolism; L-arabinan degradation.
Induction	By L-araban, arabinogalactan and L-arabitol.
Sequence similarities	Belongs to the glycosyl hydrolase 43 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological_process	arabinan catabolic process Inferred from electronic annotation. Source: UniProtKB-UniPathway
Molecular_function	arabinan endo-1,5-alpha-L-arabinosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 19	19	Ref.1
	Chain	20 – 321	302	Arabinan endo-1,5-alpha-L-arabinosidase A		PRO_0000012204
Amino acid modifications
	Glycosylation	295	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P42256 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 3087D7D0592A0B20	FASTA	321	34,455
	10 20 30 40 50 60 MYQLLSVASV PLLASLVHGY ADPGACSGVC TTHDPGLIRR ESDGTYFLFS TGNKISYVSA 70 80 90 100 110 120 SSIEGPWTSV GSMLPDGSSI DLDGNDDLWA PDVSYVDGLY YVYYAVSTFG SQDSAIGLAT 130 140 150 160 170 180 SETMEYGSWT DHGSTGIASS SAKIYNAIDP NLIYADGTYY INFGSFWDDI YQVPMKSTPT 190 200 210 220 230 240 AAASSSYNLA YDPSGTHAEE GSYMFQYGDY YYLFYSAGIC CGYDTSMPAS GEEYHIKVCR 250 260 270 280 290 300 STSPTGDFVD SDGTACTDGG GTMVLESHGE VYGPGGQGVY DDPNLGPVLY YHYMNTTIGY 310 320 ADSDAQFGWN TIDFSSGWPV V

References

[1]

"Molecular cloning, expression and structure of the endo-1,5-alpha-L-arabinase gene of Aspergillus niger." Flipphi M.J.A., Panneman H., van der Veen P., Visser J., de Graaff L.H. Appl. Microbiol. Biotechnol. 40:318-326(1993) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 20-32 AND 125-139. Strain: ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400.

Cross-references

Sequence databases
EMBL GenBank DDBJ	L23430 Genomic DNA. Translation: AAA32682.1.
3D structure databases
ProteinModelPortal	P42256.
ModBase	Search...
Protein family/group databases
CAZy	GH43. Glycoside Hydrolase Family 43.
mycoCLAP	ABN43A_ASPNG.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Phylogenomic databases
eggNOG	COG3507.
Enzyme and pathway databases
BioCyc	MetaCyc:MONOMER-16541.
UniPathway	UPA00667.
Family and domain databases
Gene3D	2.115.10.20. 1 hit.
InterPro	IPR006710. Glyco_hydro_43. IPR016840. Glyco_hydro_43_endo_a_Ara-ase. IPR023296. Glyco_hydro_beta-prop. [Graphical view]
PANTHER	PTHR22925. PTHR22925. 1 hit.
Pfam	PF04616. Glyco_hydro_43. 1 hit. [Graphical view]
PIRSF	PIRSF026534. Endo_alpha-L-arabinosidase. 1 hit.
SUPFAM	SSF75005. Glyco_hydro_43_beta-prop. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ABNA_ASPNG

Accession

Primary (citable) accession number: P42256

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 64 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program