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P42256 (ABNA_ASPNG) Reviewed, UniProtKB/Swiss-Prot

Last modified November 13, 2013. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arabinan endo-1,5-alpha-L-arabinosidase A

EC=3.2.1.99
Alternative name(s):
Endo-1,5-alpha-L-arabinanase A
Short name=ABN A
Gene names
Name:abnA
OrganismAspergillus niger
Taxonomic identifier5061 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length321 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Its preferred substrate is linear 1,5-alpha-L-arabinan. The enzyme activity is progressively reduced as 1,5-alpha-chains become shorter or more highly substituted.

Catalytic activity

Endohydrolysis of (1->5)-alpha-arabinofuranosidic linkages in (1->5)-arabinans.

Pathway

Glycan metabolism; L-arabinan degradation.

Induction

By L-araban, arabinogalactan and L-arabitol.

Sequence similarities

Belongs to the glycosyl hydrolase 43 family.

Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termDirect protein sequencing
Gene Ontology (GO)
   Biological_processarabinan catabolic process

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Molecular_functionarabinan endo-1,5-alpha-L-arabinosidase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1919 Ref.1
Chain20 – 321302Arabinan endo-1,5-alpha-L-arabinosidase A
PRO_0000012204

Amino acid modifications

Glycosylation2951N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P42256 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 3087D7D0592A0B20

FASTA32134,455
        10         20         30         40         50         60 
MYQLLSVASV PLLASLVHGY ADPGACSGVC TTHDPGLIRR ESDGTYFLFS TGNKISYVSA 

        70         80         90        100        110        120 
SSIEGPWTSV GSMLPDGSSI DLDGNDDLWA PDVSYVDGLY YVYYAVSTFG SQDSAIGLAT 

       130        140        150        160        170        180 
SETMEYGSWT DHGSTGIASS SAKIYNAIDP NLIYADGTYY INFGSFWDDI YQVPMKSTPT 

       190        200        210        220        230        240 
AAASSSYNLA YDPSGTHAEE GSYMFQYGDY YYLFYSAGIC CGYDTSMPAS GEEYHIKVCR 

       250        260        270        280        290        300 
STSPTGDFVD SDGTACTDGG GTMVLESHGE VYGPGGQGVY DDPNLGPVLY YHYMNTTIGY 

       310        320 
ADSDAQFGWN TIDFSSGWPV V 

« Hide

References

[1]"Molecular cloning, expression and structure of the endo-1,5-alpha-L-arabinase gene of Aspergillus niger."
Flipphi M.J.A., Panneman H., van der Veen P., Visser J., de Graaff L.H.
Appl. Microbiol. Biotechnol. 40:318-326(1993) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 20-32 AND 125-139.
Strain: ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L23430 Genomic DNA. Translation: AAA32682.1.

3D structure databases

ProteinModelPortalP42256.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH43. Glycoside Hydrolase Family 43.
mycoCLAPABN43A_ASPNG.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Phylogenomic databases

eggNOGCOG3507.

Enzyme and pathway databases

BioCycMetaCyc:MONOMER-16541.
UniPathwayUPA00667.

Family and domain databases

Gene3D2.115.10.20. 1 hit.
InterProIPR006710. Glyco_hydro_43.
IPR016840. Glyco_hydro_43_endo_a_Ara-ase.
IPR023296. Glyco_hydro_beta-prop.
[Graphical view]
PANTHERPTHR22925. PTHR22925. 1 hit.
PfamPF04616. Glyco_hydro_43. 1 hit.
[Graphical view]
PIRSFPIRSF026534. Endo_alpha-L-arabinosidase. 1 hit.
SUPFAMSSF75005. SSF75005. 1 hit.
ProtoNetSearch...

Entry information

Entry nameABNA_ASPNG
AccessionPrimary (citable) accession number: P42256
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 13, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries