Reviewed, UniProtKB/Swiss-Prot P42254 (ABFA_ASPNG)

Names and origin

Protein names

Recommended name:
    Alpha-N-arabinofuranosidase A
      Short name=Arabinosidase A
      Short name=ABF A
    EC=3.2.1.55

Gene names

Name:

abfA

Organism

Aspergillus niger

Taxonomic identifier

5061 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Eurotiomycetes › Eurotiomycetidae › Eurotiales › Trichocomaceae › mitosporic Trichocomaceae › Aspergillus

Protein attributes

Sequence length	628 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Acts only on small linear 1,5-alpha-linked L-arabinofuranosyl oligosaccharides.
Catalytic activity	Hydrolysis of terminal non-reducing alpha-L-arabinofuranoside residues in alpha-L-arabinosides.
Pathway	Glycan metabolism; L-arabinan degradation.
Sequence similarities	Belongs to the glycosyl hydrolase 51 family.

Ontologies

Keywords
Domain	Signal
Molecular function	Glycosidase Hydrolase
PTM	Glycoprotein
Technical term	Direct protein sequencing
Gene Ontology (GO)
Biological process	L-arabinose metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	alpha-N-arabinofuranosidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Signal peptide	1 – 25	25	Ref.1
	Chain	26 – 628	603	Alpha-N-arabinofuranosidase A		PRO_0000012216
Amino acid modifications
	Glycosylation	36	1	N-linked (GlcNAc...) Potential
	Glycosylation	51	1	N-linked (GlcNAc...) Potential
	Glycosylation	74	1	N-linked (GlcNAc...)
	Glycosylation	152	1	N-linked (GlcNAc...) Potential
	Glycosylation	171	1	N-linked (GlcNAc...) Potential
	Glycosylation	260	1	N-linked (GlcNAc...) Potential
	Glycosylation	359	1	N-linked (GlcNAc...) Potential
	Glycosylation	440	1	N-linked (GlcNAc...) Potential
	Glycosylation	493	1	N-linked (GlcNAc...) Potential
	Glycosylation	610	1	N-linked (GlcNAc...) Potential

Sequences

	Sequence		Length	Mass (Da)
	P42254-1 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 4F3E476FF93468AD	FASTA	628	67,833
	10 20 30 40 50 60 MVAFSALSGV SAVSLLLSLV QNAHGISLKV STQGGNSSSP ILYGFMFEDI NHSGDGGIYG 70 80 90 100 110 120 QMLQNPGLQG TAPNLTAWAA VGDATIAIDG DSPLTSAIPS TIKLNIADDA TGAVGLTNEG 130 140 150 160 170 180 YWGIPVDGSE FHSSFWIKGD YSGDITVRLV GNYTGTEYGS TTITHTSTAD NFTQASVKFP 190 200 210 220 230 240 TTKAPDGNVL YELTVDGSVA AGSSLNFGYL TLFGETYKSR ENGLKPQLAN VLDDMKGSFL 250 260 270 280 290 300 RFPGGNNLEG NSAENRWKWN ETIGDLCDRP GREGTWTYYN TDGLGLHEYF YWCEDLGLVP 310 320 330 340 350 360 VLGVWDGFAL ESGGNTPLTG DALTPYIDDV LNELEYILGD TSTTYGAWRA ANGQEEPWNL 370 380 390 400 410 420 TMVEIGNEDM LGGGCESYAE RFTAFYDAIH AAYPDLILIA STSEADCLPE SMPEGSWVDY 430 440 450 460 470 480 HDYSTPDGLV GQFNYFDNLN RSVPYFIGEY SRWEIDWPNM KGSVAEAVFM IGFERNSDVV 490 500 510 520 530 540 KMAAYAPLLQ LINSTQWTPD LIGYTQSPGD IFLSTSYYVQ EMFSRNRGDT IKEVTSDSDF 550 560 570 580 590 600 GPLYWVASSA GDSYYVKLAN YGSETQDLTV SIPGTSTGKL TVLADSDPDA YNSDTQTLVT 610 620 PSESTVQASN GTFTFSLPAW AVAVLAAN

References

[1]

"Arabinase gene expression in Aspergillus niger: indications for coordinated regulation." Flipphi M.J.A., Visser J., van der Veen P., de Graaff L.H. Microbiology 140:2673-2682(1994) [PubMed: 8000538] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 26-35 AND 63-77. Strain: ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400.

Cross-references

Sequence databases
EMBLGenBankDDBJ	L29005 Genomic DNA. Translation: AAC41644.1.
3D structure databases
ModBase	Search...
Protein family/group databases
CAZy	GH51. Glycoside Hydrolase Family 51.
Enzyme and pathway databases
BRENDA	3.2.1.55. 277.
Family and domain databases
InterPro	IPR010720. Alpha-L-AF_C. [Graphical view]
Pfam	PF06964. Alpha-L-AF_C. 1 hit. [Graphical view]
SMART	SM00813. Alpha-L-AF_C. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

ABFA_ASPNG

Accession

Primary (citable) accession number: P42254

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	June 16, 2009
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)