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P42236

- ALDH1_BACSU

UniProt

P42236 - ALDH1_BACSU

Protein

Probable aldehyde dehydrogenase YcbD

Gene

ycbD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 103 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    An aldehyde + NAD+ + H2O = a carboxylate + NADH.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei255 – 2551By similarity
    Active sitei289 – 2891By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi233 – 2386NADBy similarity

    GO - Molecular functioni

    1. aldehyde dehydrogenase (NAD) activity Source: UniProtKB-EC

    GO - Biological processi

    1. ethanol catabolic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Ligandi

    NAD

    Enzyme and pathway databases

    BioCyciBSUB:BSU02470-MONOMER.
    RETL1328306-WGS:GSTH-3212-MONOMER.
    UniPathwayiUPA00780; UER00768.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Probable aldehyde dehydrogenase YcbD (EC:1.2.1.3)
    Gene namesi
    Name:ycbD
    Ordered Locus Names:BSU02470
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU02470.

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 488488Probable aldehyde dehydrogenase YcbDPRO_0000056444Add
    BLAST

    Proteomic databases

    PaxDbiP42236.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU02470.

    Structurei

    3D structure databases

    ProteinModelPortaliP42236.
    SMRiP42236. Positions 7-487.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the aldehyde dehydrogenase family.Curated

    Phylogenomic databases

    eggNOGiCOG1012.
    HOGENOMiHOG000271511.
    KOiK00128.
    OMAiHPEVTYG.
    OrthoDBiEOG6BS8QW.
    PhylomeDBiP42236.

    Family and domain databases

    Gene3Di3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProiIPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view]
    PfamiPF00171. Aldedh. 1 hit.
    [Graphical view]
    SUPFAMiSSF53720. SSF53720. 1 hit.
    PROSITEiPS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P42236-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSVITEQNTY LNFINGEWVK SQSGDMVKVE NPADVNDIVG YVQNSTAEDV    50
    ERAVTAANEA KTAWRKLTGA ERGQYLYKTA DIMEQRLEEI AACATREMGK 100
    TLPEAKGETA RGIAILRYYA GEGMRKTGDV IPSTDKDALM FTTRVPLGVV 150
    GVISPWNFPV AIPIWKMAPA LVYGNTVVIK PATETAVTCA KIIACFEEAG 200
    LPAGVINLVT GPGSVVGQGL AEHDGVNAVT FTGSNQVGKI IGQAALARGA 250
    KYQLEMGGKN PVIVADDADL EAAAEAVITG AFRSTGQKCT ATSRVIVQSG 300
    IYERFKEKLL QRTKDITIGD SLKEDVWMGP IASKNQLDNC LSYIEKGKQE 350
    GASLLIGGEK LENGKYQNGY YVQPAIFDNV TSEMTIAQEE IFGPVIALIK 400
    VDSIEEALNI ANDVKFGLSA SIFTENIGRM LSFIDEIDAG LVRINAESAG 450
    VELQAPFGGM KQSSSHSREQ GEAAKDFFTA IKTVFVKP 488
    Length:488
    Mass (Da):52,415
    Last modified:November 1, 1995 - v1
    Checksum:i9C37B32EF51D59B2
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D30808 Genomic DNA. Translation: BAA06468.1.
    AL009126 Genomic DNA. Translation: CAB12041.1.
    PIRiG69752.
    RefSeqiNP_388129.1. NC_000964.3.
    WP_003246263.1. NZ_CM000487.1.

    Genome annotation databases

    EnsemblBacteriaiCAB12041; CAB12041; BSU02470.
    GeneIDi938406.
    KEGGibsu:BSU02470.
    PATRICi18972045. VBIBacSub10457_0251.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D30808 Genomic DNA. Translation: BAA06468.1 .
    AL009126 Genomic DNA. Translation: CAB12041.1 .
    PIRi G69752.
    RefSeqi NP_388129.1. NC_000964.3.
    WP_003246263.1. NZ_CM000487.1.

    3D structure databases

    ProteinModelPortali P42236.
    SMRi P42236. Positions 7-487.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU02470.

    Proteomic databases

    PaxDbi P42236.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB12041 ; CAB12041 ; BSU02470 .
    GeneIDi 938406.
    KEGGi bsu:BSU02470.
    PATRICi 18972045. VBIBacSub10457_0251.

    Organism-specific databases

    GenoListi BSU02470.

    Phylogenomic databases

    eggNOGi COG1012.
    HOGENOMi HOG000271511.
    KOi K00128.
    OMAi HPEVTYG.
    OrthoDBi EOG6BS8QW.
    PhylomeDBi P42236.

    Enzyme and pathway databases

    UniPathwayi UPA00780 ; UER00768 .
    BioCyci BSUB:BSU02470-MONOMER.
    RETL1328306-WGS:GSTH-3212-MONOMER.

    Family and domain databases

    Gene3Di 3.40.309.10. 1 hit.
    3.40.605.10. 1 hit.
    InterProi IPR016161. Ald_DH/histidinol_DH.
    IPR016163. Ald_DH_C.
    IPR016160. Ald_DH_CS_CYS.
    IPR029510. Ald_DH_CS_GLU.
    IPR016162. Ald_DH_N.
    IPR015590. Aldehyde_DH_dom.
    [Graphical view ]
    Pfami PF00171. Aldedh. 1 hit.
    [Graphical view ]
    SUPFAMi SSF53720. SSF53720. 1 hit.
    PROSITEi PS00070. ALDEHYDE_DEHYDR_CYS. 1 hit.
    PS00687. ALDEHYDE_DEHYDR_GLU. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Determination of a 21548 bp nucleotide sequence around the 24 degrees region of the Bacillus subtilis chromosome."
      Ogawa K., Akagawa E., Nakamura K., Yamane K.
      Microbiology 141:269-275(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    2. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.

    Entry informationi

    Entry nameiALDH1_BACSU
    AccessioniPrimary (citable) accession number: P42236
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 103 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3