Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative aldehyde dehydrogenase YcbD

Gene

ycbD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

An aldehyde + NAD+ + H2O = a carboxylate + NADH.PROSITE-ProRule annotation

Pathwayi: ethanol degradation

This protein is involved in step 2 of the subpathway that synthesizes acetate from ethanol.
Proteins known to be involved in the 2 steps of the subpathway in this organism are:
  1. no protein annotated in this organism
  2. Putative aldehyde dehydrogenase YcbD (ycbD)
This subpathway is part of the pathway ethanol degradation, which is itself part of Alcohol metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes acetate from ethanol, the pathway ethanol degradation and in Alcohol metabolism.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei255PROSITE-ProRule annotation1
Active sitei289PROSITE-ProRule annotation1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi233 – 238NADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Enzyme and pathway databases

BioCyciBSUB:BSU02470-MONOMER
SABIO-RKP42236
UniPathwayiUPA00780; UER00768

Names & Taxonomyi

Protein namesi
Recommended name:
Putative aldehyde dehydrogenase YcbDPROSITE-ProRule annotation (EC:1.2.1.3PROSITE-ProRule annotation)
Gene namesi
Name:ycbD
Ordered Locus Names:BSU02470
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Pathology & Biotechi

Disruption phenotypei

No effect on vanillin degradation.1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000564441 – 488Putative aldehyde dehydrogenase YcbDAdd BLAST488

Proteomic databases

PaxDbiP42236
PRIDEiP42236

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100001368

Structurei

3D structure databases

ProteinModelPortaliP42236
SMRiP42236
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the aldehyde dehydrogenase family.Curated

Phylogenomic databases

eggNOGiENOG4105C26 Bacteria
COG1012 LUCA
HOGENOMiHOG000271511
InParanoidiP42236
KOiK22187
OMAiWNFPLDM
PhylomeDBiP42236

Family and domain databases

Gene3Di3.40.309.10, 1 hit
3.40.605.10, 2 hits
InterProiView protein in InterPro
IPR016161 Ald_DH/histidinol_DH
IPR016163 Ald_DH_C
IPR016160 Ald_DH_CS_CYS
IPR029510 Ald_DH_CS_GLU
IPR016162 Ald_DH_N
IPR015590 Aldehyde_DH_dom
PfamiView protein in Pfam
PF00171 Aldedh, 1 hit
SUPFAMiSSF53720 SSF53720, 1 hit
PROSITEiView protein in PROSITE
PS00070 ALDEHYDE_DEHYDR_CYS, 1 hit
PS00687 ALDEHYDE_DEHYDR_GLU, 1 hit

Sequencei

Sequence statusi: Complete.

P42236-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSVITEQNTY LNFINGEWVK SQSGDMVKVE NPADVNDIVG YVQNSTAEDV
60 70 80 90 100
ERAVTAANEA KTAWRKLTGA ERGQYLYKTA DIMEQRLEEI AACATREMGK
110 120 130 140 150
TLPEAKGETA RGIAILRYYA GEGMRKTGDV IPSTDKDALM FTTRVPLGVV
160 170 180 190 200
GVISPWNFPV AIPIWKMAPA LVYGNTVVIK PATETAVTCA KIIACFEEAG
210 220 230 240 250
LPAGVINLVT GPGSVVGQGL AEHDGVNAVT FTGSNQVGKI IGQAALARGA
260 270 280 290 300
KYQLEMGGKN PVIVADDADL EAAAEAVITG AFRSTGQKCT ATSRVIVQSG
310 320 330 340 350
IYERFKEKLL QRTKDITIGD SLKEDVWMGP IASKNQLDNC LSYIEKGKQE
360 370 380 390 400
GASLLIGGEK LENGKYQNGY YVQPAIFDNV TSEMTIAQEE IFGPVIALIK
410 420 430 440 450
VDSIEEALNI ANDVKFGLSA SIFTENIGRM LSFIDEIDAG LVRINAESAG
460 470 480
VELQAPFGGM KQSSSHSREQ GEAAKDFFTA IKTVFVKP
Length:488
Mass (Da):52,415
Last modified:November 1, 1995 - v1
Checksum:i9C37B32EF51D59B2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D30808 Genomic DNA Translation: BAA06468.1
AL009126 Genomic DNA Translation: CAB12041.1
PIRiG69752
RefSeqiNP_388129.1, NC_000964.3
WP_003246263.1, NZ_JNCM01000030.1

Genome annotation databases

EnsemblBacteriaiCAB12041; CAB12041; BSU02470
GeneIDi938406
KEGGibsu:BSU02470
PATRICifig|224308.179.peg.254

Similar proteinsi

Entry informationi

Entry nameiALDH1_BACSU
AccessioniPrimary (citable) accession number: P42236
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health