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Protein

L-cystine-binding protein TcyA

Gene

tcyA

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Part of the ABC transporter complex TcyABC involved in L-cystine import.1 Publication

GO - Biological processi

Keywordsi

Biological processAmino-acid transport, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU03610-MONOMER

Protein family/group databases

TCDBi3.A.1.3.14 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
L-cystine-binding protein TcyA
Gene namesi
Name:tcyA
Synonyms:yckK
Ordered Locus Names:BSU03610
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 19PROSITE-ProRule annotationAdd BLAST19
ChainiPRO_000003177820 – 268L-cystine-binding protein TcyAAdd BLAST249

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi20N-palmitoyl cysteinePROSITE-ProRule annotation1
Lipidationi20S-diacylglycerol cysteinePROSITE-ProRule annotation1

Keywords - PTMi

Lipoprotein, Palmitate

Proteomic databases

PaxDbiP42199
PRIDEiP42199

Interactioni

Subunit structurei

The complex is composed of two ATP-binding proteins (TcyC), two transmembrane proteins (TcyB) and a solute-binding protein (TcyA).Curated

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100002048

Structurei

3D structure databases

ProteinModelPortaliP42199
SMRiP42199
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiCOG0834 LUCA
HOGENOMiHOG000031895
InParanoidiP42199
KOiK02424
OMAiKFVPTKW
PhylomeDBiP42199

Family and domain databases

InterProiView protein in InterPro
IPR018313 SBP_3_CS
IPR001638 Solute-binding_3/MltF_N
PfamiView protein in Pfam
PF00497 SBP_bac_3, 1 hit
SMARTiView protein in SMART
SM00062 PBPb, 1 hit
PROSITEiView protein in PROSITE
PS51257 PROKAR_LIPOPROTEIN, 1 hit
PS01039 SBP_BACTERIAL_3, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P42199-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKALLALFM VVSIAALAAC GAGNDNQSKD NAKDGDLWAS IKKKGVLTVG
60 70 80 90 100
TEGTYEPFTY HDKDTDKLTG YDVEVITEVA KRLGLKVDFK ETQWDSMFAG
110 120 130 140 150
LNSKRFDVVA NQVGKTDRED KYDFSDKYTT SRAVVVTKKD NNDIKSEADV
160 170 180 190 200
KGKTSAQSLT SNYNKLATNA GAKVEGVEGM AQALQMIQQG RVDMTYNDKL
210 220 230 240 250
AVLNYLKTSG NKNVKIAFET GEPQSTYFTF RKGSGEVVDQ VNKALKEMKE
260
DGTLSKISKK WFGEDVSK
Length:268
Mass (Da):29,514
Last modified:June 16, 2009 - v3
Checksum:iE88B56676E8AD762
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti81 – 82KR → NS in CAA54724 (PubMed:7551042).Curated2
Sequence conflicti95D → G in BAA08994 (PubMed:8969502).Curated1
Sequence conflicti120 – 121DK → NQ in CAA54724 (PubMed:7551042).Curated2
Sequence conflicti190G → A in BAA08994 (PubMed:8969502).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X77636 Genomic DNA Translation: CAA54724.1
D50453 Genomic DNA Translation: BAA08994.1
AL009126 Genomic DNA Translation: CAB12155.2
PIRiE69761
RefSeqiNP_388243.2, NC_000964.3
WP_003246699.1, NZ_JNCM01000031.1

Genome annotation databases

EnsemblBacteriaiCAB12155; CAB12155; BSU03610
GeneIDi938298
KEGGibsu:BSU03610
PATRICifig|224308.179.peg.380

Similar proteinsi

Entry informationi

Entry nameiTCYA_BACSU
AccessioniPrimary (citable) accession number: P42199
Secondary accession number(s): P94402
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 16, 2009
Last modified: May 23, 2018
This is version 114 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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