Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Sensory rhodopsin-2

Gene

sop2

Organism
Natronomonas pharaonis (Natronobacterium pharaonis)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Photophobic photoreceptor responsible for the negative phototaxis. Activates the sensory rhodopsin II transducer (HTR-II) in response to blue light.3 Publications

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Photoreceptor protein, Receptor, Retinal protein

Keywords - Biological processi

Keywords - Ligandi

Chromophore

Protein family/group databases

TCDBi3.E.1.3.3. the ion-translocating microbial rhodopsin (mr) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sensory rhodopsin-2
Alternative name(s):
Sensory rhodopsin II
Short name:
SR-II
Gene namesi
Name:sop2
Synonyms:sopII
OrganismiNatronomonas pharaonis (Natronobacterium pharaonis)
Taxonomic identifieri2257 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaHalobacteriaHalobacterialesHalobacteriaceaeNatronomonas

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini1 – 3Extracellular3
Transmembranei4 – 25Helical; Name=Helix AAdd BLAST22
Topological domaini26 – 33Cytoplasmic8
Transmembranei34 – 55Helical; Name=Helix BAdd BLAST22
Topological domaini56 – 69ExtracellularAdd BLAST14
Transmembranei70 – 91Helical; Name=Helix CAdd BLAST22
Topological domaini92 – 94Cytoplasmic3
Transmembranei95 – 117Helical; Name=Helix DAdd BLAST23
Topological domaini118 – 121Extracellular4
Transmembranei122 – 149Helical; Name=Helix EAdd BLAST28
Topological domaini150 – 153Cytoplasmic4
Transmembranei154 – 181Helical; Name=Helix FAdd BLAST28
Topological domaini182 – 189Extracellular8
Transmembranei190 – 222Helical; Name=Helix GAdd BLAST33
Topological domaini223 – 239CytoplasmicAdd BLAST17

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001962821 – 239Sensory rhodopsin-2Add BLAST239

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei205N6-(retinylidene)lysine1

Interactioni

Subunit structurei

Homodimer. Interacts with HTR-II.2 Publications

Protein-protein interaction databases

DIPiDIP-35282N.
IntActiP42196. 1 interactor.
MINTiMINT-248654.
STRINGi348780.NP4834A.

Structurei

Secondary structure

1239
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Helixi2 – 26Combined sources25
Turni31 – 33Combined sources3
Helixi34 – 55Combined sources22
Turni56 – 59Combined sources4
Beta strandi60 – 63Combined sources4
Beta strandi66 – 69Combined sources4
Helixi70 – 91Combined sources22
Helixi95 – 117Combined sources23
Helixi123 – 142Combined sources20
Helixi144 – 149Combined sources6
Helixi154 – 171Combined sources18
Helixi173 – 180Combined sources8
Turni182 – 185Combined sources4
Helixi190 – 218Combined sources29

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GU8X-ray2.27A1-239[»]
1GUEX-ray2.27A1-239[»]
1H2SX-ray1.93A1-225[»]
1H68X-ray2.10A1-239[»]
1JGJX-ray2.40A1-217[»]
2F93X-ray2.00A2-239[»]
2F95X-ray2.20A2-239[»]
3QAPX-ray1.90A1-239[»]
3QDCX-ray2.50A1-239[»]
4GYCX-ray2.05A1-239[»]
ProteinModelPortaliP42196.
SMRiP42196.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP42196.

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiarCOG02810. Archaea.
COG5524. LUCA.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhodopsins.
IPR018229. Rhodopsin_retinal_BS.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
PRINTSiPR00251. BACTRLOPSIN.
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]
PROSITEiPS00950. BACTERIAL_OPSIN_1. 1 hit.
PS00327. BACTERIAL_OPSIN_RET. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42196-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVGLTTLFWL GAIGMLVGTL AFAWAGRDAG SGERRYYVTL VGISGIAAVA
60 70 80 90 100
YVVMALGVGW VPVAERTVFA PRYIDWILTT PLIVYFLGLL AGLDSREFGI
110 120 130 140 150
VITLNTVVML AGFAGAMVPG IERYALFGMG AVAFLGLVYY LVGPMTESAS
160 170 180 190 200
QRSSGIKSLY VRLRNLTVIL WAIYPFIWLL GPPGVALLTP TVDVALIVYL
210 220 230
DLVTKVGFGF IALDAAATLR AEHGESLAGV DTDAPAVAD
Length:239
Mass (Da):25,355
Last modified:November 1, 1995 - v1
Checksum:iC0E93EAF341B6B19
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z35086 Genomic DNA. Translation: CAA84469.1.
PIRiS55300.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z35086 Genomic DNA. Translation: CAA84469.1.
PIRiS55300.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1GU8X-ray2.27A1-239[»]
1GUEX-ray2.27A1-239[»]
1H2SX-ray1.93A1-225[»]
1H68X-ray2.10A1-239[»]
1JGJX-ray2.40A1-217[»]
2F93X-ray2.00A2-239[»]
2F95X-ray2.20A2-239[»]
3QAPX-ray1.90A1-239[»]
3QDCX-ray2.50A1-239[»]
4GYCX-ray2.05A1-239[»]
ProteinModelPortaliP42196.
SMRiP42196.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

DIPiDIP-35282N.
IntActiP42196. 1 interactor.
MINTiMINT-248654.
STRINGi348780.NP4834A.

Protein family/group databases

TCDBi3.E.1.3.3. the ion-translocating microbial rhodopsin (mr) family.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiarCOG02810. Archaea.
COG5524. LUCA.

Miscellaneous databases

EvolutionaryTraceiP42196.

Family and domain databases

InterProiIPR001425. Arc/bac/fun_rhodopsins.
IPR018229. Rhodopsin_retinal_BS.
[Graphical view]
PfamiPF01036. Bac_rhodopsin. 1 hit.
[Graphical view]
PRINTSiPR00251. BACTRLOPSIN.
SMARTiSM01021. Bac_rhodopsin. 1 hit.
[Graphical view]
PROSITEiPS00950. BACTERIAL_OPSIN_1. 1 hit.
PS00327. BACTERIAL_OPSIN_RET. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiBACS2_NATPH
AccessioniPrimary (citable) accession number: P42196
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.