##gff-version 3
P42124	UniProtKB	Chain	1	760	.	.	.	ID=PRO_0000213989;Note=Histone-lysine N-methyltransferase E(z)	
P42124	UniProtKB	Domain	443	491	.	.	.	Note=SANT	
P42124	UniProtKB	Domain	518	619	.	.	.	Note=CXC;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00970	
P42124	UniProtKB	Domain	626	741	.	.	.	Note=SET;Ontology_term=ECO:0000255;evidence=ECO:0000255|PROSITE-ProRule:PRU00190	
P42124	UniProtKB	Region	195	245	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P42124	UniProtKB	Region	382	417	.	.	.	Note=Disordered;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P42124	UniProtKB	Motif	505	510	.	.	.	Note=Nuclear localization signal;Ontology_term=ECO:0000255;evidence=ECO:0000255	
P42124	UniProtKB	Compositional bias	196	241	.	.	.	Note=Basic and acidic residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P42124	UniProtKB	Compositional bias	387	409	.	.	.	Note=Polar residues;Ontology_term=ECO:0000256;evidence=ECO:0000256|SAM:MobiDB-lite	
P42124	UniProtKB	Modified residue	493	493	.	.	.	Note=Phosphoserine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18327897;Dbxref=PMID:18327897	
P42124	UniProtKB	Modified residue	502	502	.	.	.	Note=Phosphothreonine;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:18327897;Dbxref=PMID:18327897	
P42124	UniProtKB	Mutagenesis	699	699	.	.	.	Note=Strongly reduces methyltransferase activity of the Esc/E(z) complex. R->A%2CH;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12408864;Dbxref=PMID:12408864	
P42124	UniProtKB	Mutagenesis	702	703	.	.	.	Note=Abolishes methyltransferase activity of the Esc/E(z) complex. NH->AA;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12408863;Dbxref=PMID:12408863	
P42124	UniProtKB	Mutagenesis	703	703	.	.	.	Note=Strongly reduces methyltransferase activity of the Esc/E(z) complex. H->A%2CK;Ontology_term=ECO:0000269;evidence=ECO:0000269|PubMed:12408864;Dbxref=PMID:12408864	
P42124	UniProtKB	Sequence conflict	185	187	.	.	.	Note=GTA->STS;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	194	194	.	.	.	Note=T->P;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	213	213	.	.	.	Note=G->C;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	223	223	.	.	.	Note=D->E;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	230	230	.	.	.	Note=E->D;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	240	240	.	.	.	Note=L->V;Ontology_term=ECO:0000305;evidence=ECO:0000305	
P42124	UniProtKB	Sequence conflict	250	250	.	.	.	Note=D->A;Ontology_term=ECO:0000305;evidence=ECO:0000305