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P42086

- PBUX_BACSU

UniProt

P42086 - PBUX_BACSU

Protein

Xanthine permease

Gene

pbuX

Organism
Bacillus subtilis (strain 168)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 103 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Transport of xanthine in the cell.

    GO - Molecular functioni

    1. transporter activity Source: InterPro

    GO - Biological processi

    1. transmembrane transport Source: InterPro

    Keywords - Biological processi

    Transport

    Enzyme and pathway databases

    BioCyciBSUB:BSU22060-MONOMER.

    Protein family/group databases

    TCDBi2.A.40.3.1. the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Xanthine permease
    Gene namesi
    Name:pbuX
    Synonyms:ypaQ
    Ordered Locus Names:BSU22060
    OrganismiBacillus subtilis (strain 168)
    Taxonomic identifieri224308 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
    ProteomesiUP000001570: Chromosome

    Organism-specific databases

    GenoListiBSU22060. [Micado]

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cell membrane, Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 438438Xanthine permeasePRO_0000165962Add
    BLAST

    Proteomic databases

    PaxDbiP42086.

    Interactioni

    Protein-protein interaction databases

    STRINGi224308.BSU22060.

    Structurei

    3D structure databases

    ProteinModelPortaliP42086.
    SMRiP42086. Positions 1-419.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei11 – 3121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei41 – 6121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei65 – 8521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei100 – 12021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei121 – 14121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei154 – 17421HelicalSequence AnalysisAdd
    BLAST
    Transmembranei180 – 20021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei220 – 24021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei272 – 29221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei308 – 32821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei331 – 35121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei367 – 38721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei396 – 41621HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG2233.
    HOGENOMiHOG000038199.
    KOiK16169.
    OMAiTLMPVAM.
    OrthoDBiEOG6M6JJK.
    PhylomeDBiP42086.

    Family and domain databases

    InterProiIPR017588. Xan_permease.
    IPR006042. Xan_ur_permease.
    IPR006043. Xant/urac/vitC.
    [Graphical view]
    PANTHERiPTHR11119. PTHR11119. 1 hit.
    PfamiPF00860. Xan_ur_permease. 1 hit.
    [Graphical view]
    TIGRFAMsiTIGR00801. ncs2. 1 hit.
    TIGR03173. pbuX. 1 hit.
    PROSITEiPS01116. XANTH_URACIL_PERMASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P42086-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRNGFGKTLS LGIQHVLAMY AGAIVVPLIV GKAMGLTVEQ LTYLVSIDIF    50
    MCGVATLLQV WSNRFFGIGL PVVLGCTFTA VSPMIAIGSE YGVSTVYGSI 100
    IASGILVILI SFFFGKLVSF FPPVVTGSVV TIIGITLMPV AMNNMAGGEG 150
    SADFGDLSNL ALAFTVLSII VLLYRFTKGF IKSVSILIGI LIGTFIAYFM 200
    GKVQFDNVSD AAVVQMIQPF YFGAPSFHAA PIITMSIVAI VSLVESTGVY 250
    FALGDLTNRR LTEIDLSKGY RAEGLAVLLG GIFNAFPYTA FSQNVGLVQL 300
    TGIKKNAVIV VTGVILMAFG LFPKIAAFTT IIPSAVLGGA MVAMFGMVIA 350
    YGIKMLSRID FAKQENLLIV ACSVGLGLGV TVVPDIFKQL PSALTLLTTN 400
    GIVAGSFTAV VLNIVYNVFS KAKKIEQEAD LAEQKTAV 438
    Length:438
    Mass (Da):46,238
    Last modified:November 1, 1995 - v1
    Checksum:iAFB9EDFADFF12E29
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X83878 Genomic DNA. Translation: CAA58759.1.
    L77246 Genomic DNA. Translation: AAA96612.1.
    AL009126 Genomic DNA. Translation: CAB14123.1.
    PIRiS51310.
    RefSeqiNP_390088.1. NC_000964.3.

    Genome annotation databases

    EnsemblBacteriaiCAB14123; CAB14123; BSU22060.
    GeneIDi939068.
    KEGGibsu:BSU22060.
    PATRICi18976219. VBIBacSub10457_2300.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X83878 Genomic DNA. Translation: CAA58759.1 .
    L77246 Genomic DNA. Translation: AAA96612.1 .
    AL009126 Genomic DNA. Translation: CAB14123.1 .
    PIRi S51310.
    RefSeqi NP_390088.1. NC_000964.3.

    3D structure databases

    ProteinModelPortali P42086.
    SMRi P42086. Positions 1-419.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 224308.BSU22060.

    Protein family/group databases

    TCDBi 2.A.40.3.1. the nucleobase/ascorbate transporter (nat) or nucleobase:cation symporter-2 (ncs2) family.

    Proteomic databases

    PaxDbi P42086.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAB14123 ; CAB14123 ; BSU22060 .
    GeneIDi 939068.
    KEGGi bsu:BSU22060.
    PATRICi 18976219. VBIBacSub10457_2300.

    Organism-specific databases

    GenoListi BSU22060. [Micado ]

    Phylogenomic databases

    eggNOGi COG2233.
    HOGENOMi HOG000038199.
    KOi K16169.
    OMAi TLMPVAM.
    OrthoDBi EOG6M6JJK.
    PhylomeDBi P42086.

    Enzyme and pathway databases

    BioCyci BSUB:BSU22060-MONOMER.

    Family and domain databases

    InterProi IPR017588. Xan_permease.
    IPR006042. Xan_ur_permease.
    IPR006043. Xant/urac/vitC.
    [Graphical view ]
    PANTHERi PTHR11119. PTHR11119. 1 hit.
    Pfami PF00860. Xan_ur_permease. 1 hit.
    [Graphical view ]
    TIGRFAMsi TIGR00801. ncs2. 1 hit.
    TIGR03173. pbuX. 1 hit.
    PROSITEi PS01116. XANTH_URACIL_PERMASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Xanthine metabolism in Bacillus subtilis: characterization of the xpt-pbuX operon and evidence for purine- and nitrogen-controlled expression of genes involved in xanthine salvage and catabolism."
      Christiansen L.C., Schou S., Nygaard P., Saxild H.H.
      J. Bacteriol. 179:2540-2550(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168.
    2. "Organization of the Bacillus subtilis 168 chromosome between kdg and the attachment site of the SP beta prophage: use of long accurate PCR and yeast artificial chromosomes for sequencing."
      Capuano V., Galleron N., Pujic P., Sorokin A., Ehrlich S.D.
      Microbiology 142:3005-3015(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: 168 / Marburg / ATCC 6051 / DSM 10 / JCM 1465 / NBRC 13719 / NCIMB 3610 / VKM B-501.
    3. "The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
      Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V.
      , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
      Nature 390:249-256(1997) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 168.

    Entry informationi

    Entry nameiPBUX_BACSU
    AccessioniPrimary (citable) accession number: P42086
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 103 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Bacillus subtilis
      Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3