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P42083

- YKCA_CAEEL

UniProt

P42083 - YKCA_CAEEL

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Protein

Putative tyrosine-protein phosphatase B0280.11

Gene
B0280.11
Organism
Caenorhabditis elegans
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei337 – 3371Phosphocysteine intermediate By similarity

GO - Molecular functioni

  1. protein tyrosine phosphatase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase B0280.11 (EC:3.1.3.48)
Gene namesi
ORF Names:B0280.11
OrganismiCaenorhabditis elegans
Taxonomic identifieri6239 [NCBI]
Taxonomic lineageiEukaryotaMetazoaEcdysozoaNematodaChromadoreaRhabditidaRhabditoideaRhabditidaePeloderinaeCaenorhabditis
ProteomesiUP000001940: Chromosome III

Organism-specific databases

WormBaseiB0280.11; CE39312; WBGene00015106.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 441441Putative tyrosine-protein phosphatase B0280.11PRO_0000094926Add
BLAST

Proteomic databases

PRIDEiP42083.

Interactioni

Protein-protein interaction databases

STRINGi6239.B0280.11.

Structurei

3D structure databases

ProteinModelPortaliP42083.
SMRiP42083. Positions 136-400.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini142 – 400259Tyrosine-protein phosphataseAdd
BLAST

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi3 – 9189Lys-richAdd
BLAST
Compositional biasi17 – 226Poly-Lys

Sequence similaritiesi

Phylogenomic databases

eggNOGiNOG270825.
GeneTreeiENSGT00530000064500.
HOGENOMiHOG000125385.
InParanoidiP42083.
OMAiFETFACA.
OrthoDBiEOG74N5MR.
PhylomeDBiP42083.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamiPF00102. Y_phosphatase. 1 hit.
[Graphical view]
SMARTiSM00194. PTPc. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
PROSITEiPS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42083-1 [UniParc]FASTAAdd to Basket

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MEKKKSKTNL LQKFADKFKK KKRSRSAPTS KERTSEISKR KSRSPSKSKV    50
TTGNSHGAST DNKTKTDTNR MEVTAKGFKK AKDAKKLEKK KEETGPSKTP 100
STIALRRAES QMELSGNRKN VEKGVKTWVE QLEKLVEIRK LLEADFKPID 150
TMKVDLEKCQ AFKKNIDYCQ SENVELYDAN RVKGGGEADF FYHATVTSIP 200
SISTKSTILA QLPLSDSPHS LESFWLMVAA QKIQRLFILI GEDELDKAAL 250
SEYFPEDFKE FKTIRVNNRK TVSKSDEQPN TQLYYEVVPK DCAEAPFAMI 300
EICDFWPDGK IPTVSYGRIA ATAASVFDSD IDSDATCAIV SNYGAGRAGS 350
FLVGVQAIEK LQAGDAPNIK EIAMSIRSQR PCAIETLPQY VFTYIIALTY 400
GLKHVKDPVL KSKTEKVISQ LEQFACEKMM EEDEEDNTTC E 441
Length:441
Mass (Da):49,492
Last modified:May 2, 2006 - v3
Checksum:iD5AC5DB5F506F43E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080148 Genomic DNA. Translation: CCD61607.1.
PIRiT15305.
RefSeqiNP_498560.2. NM_066159.2.
UniGeneiCel.34018.

Genome annotation databases

EnsemblMetazoaiB0280.11; B0280.11; WBGene00015106.
GeneIDi175997.
KEGGicel:CELE_B0280.11.
UCSCiB0280.11. c. elegans.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
FO080148 Genomic DNA. Translation: CCD61607.1 .
PIRi T15305.
RefSeqi NP_498560.2. NM_066159.2.
UniGenei Cel.34018.

3D structure databases

ProteinModelPortali P42083.
SMRi P42083. Positions 136-400.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 6239.B0280.11.

Proteomic databases

PRIDEi P42083.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblMetazoai B0280.11 ; B0280.11 ; WBGene00015106 .
GeneIDi 175997.
KEGGi cel:CELE_B0280.11.
UCSCi B0280.11. c. elegans.

Organism-specific databases

CTDi 175997.
WormBasei B0280.11 ; CE39312 ; WBGene00015106 .

Phylogenomic databases

eggNOGi NOG270825.
GeneTreei ENSGT00530000064500.
HOGENOMi HOG000125385.
InParanoidi P42083.
OMAi FETFACA.
OrthoDBi EOG74N5MR.
PhylomeDBi P42083.

Miscellaneous databases

NextBioi 890662.

Family and domain databases

Gene3Di 3.90.190.10. 1 hit.
InterProi IPR029021. Prot-tyrosine_phosphatase-like.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view ]
Pfami PF00102. Y_phosphatase. 1 hit.
[Graphical view ]
SMARTi SM00194. PTPc. 1 hit.
[Graphical view ]
SUPFAMi SSF52799. SSF52799. 1 hit.
PROSITEi PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of the nematode C. elegans: a platform for investigating biology."
    The C. elegans sequencing consortium
    Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Bristol N2.

Entry informationi

Entry nameiYKCA_CAEEL
AccessioniPrimary (citable) accession number: P42083
Secondary accession number(s): Q2V4X3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: May 2, 2006
Last modified: June 11, 2014
This is version 100 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Caenorhabditis elegans
    Caenorhabditis elegans: entries, gene names and cross-references to WormBase
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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