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P42083 (YKCA_CAEEL) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 92. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Putative tyrosine-protein phosphatase B0280.11
EC=3.1.3.48
Gene names
ORF Names:B0280.11
OrganismCaenorhabditis elegans [Reference proteome]
Taxonomic identifier6239 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Ecdysozoa › Nematoda › Chromadorea › Rhabditida › Rhabditoidea › Rhabditidae › Peloderinae › Caenorhabditis

Protein attributes

Sequence length441 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sequence similarities

Belongs to the protein-tyrosine phosphatase family. Non-receptor class dual specificity subfamily.

Contains 1 tyrosine-protein phosphatase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 441441Putative tyrosine-protein phosphatase B0280.11
PRO_0000094926

Regions

Domain142 – 400259Tyrosine-protein phosphatase
Compositional bias3 – 9189Lys-rich
Compositional bias17 – 226Poly-Lys

Sites

Active site3371Phosphocysteine intermediate By similarity

Sequences

Sequence LengthMass (Da)Tools
P42083 [UniParc].

Last modified May 2, 2006. Version 3.
Checksum: D5AC5DB5F506F43E

FASTA44149,492
        10         20         30         40         50         60 
MEKKKSKTNL LQKFADKFKK KKRSRSAPTS KERTSEISKR KSRSPSKSKV TTGNSHGAST 

        70         80         90        100        110        120 
DNKTKTDTNR MEVTAKGFKK AKDAKKLEKK KEETGPSKTP STIALRRAES QMELSGNRKN 

       130        140        150        160        170        180 
VEKGVKTWVE QLEKLVEIRK LLEADFKPID TMKVDLEKCQ AFKKNIDYCQ SENVELYDAN 

       190        200        210        220        230        240 
RVKGGGEADF FYHATVTSIP SISTKSTILA QLPLSDSPHS LESFWLMVAA QKIQRLFILI 

       250        260        270        280        290        300 
GEDELDKAAL SEYFPEDFKE FKTIRVNNRK TVSKSDEQPN TQLYYEVVPK DCAEAPFAMI 

       310        320        330        340        350        360 
EICDFWPDGK IPTVSYGRIA ATAASVFDSD IDSDATCAIV SNYGAGRAGS FLVGVQAIEK 

       370        380        390        400        410        420 
LQAGDAPNIK EIAMSIRSQR PCAIETLPQY VFTYIIALTY GLKHVKDPVL KSKTEKVISQ 

       430        440 
LEQFACEKMM EEDEEDNTTC E

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References

[1]"Genome sequence of the nematode C. elegans: a platform for investigating biology."
The C. elegans sequencing consortium
Science 282:2012-2018(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Bristol N2.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		FO080148 Genomic DNA. Translation: CCD61607.1.
PIRT15305.
RefSeqNP_498560.2. NM_066159.2.
UniGeneCel.34018.

3D structure databases

ProteinModelPortalP42083.
SMRP42083. Positions 136-400.
ModBaseSearch...

Protein-protein interaction databases

STRING6239.B0280.11.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaB0280.11; B0280.11; B0280.11.
GeneID175997.
KEGGcel:CELE_B0280.11.
UCSCB0280.11. c. elegans.

Organism-specific databases

CTD175997.
WormBaseB0280.11; CE39312; WBGene00015106.

Phylogenomic databases

eggNOGNOG270825.
GeneTreeENSGT00530000064500.
HOGENOMHOG000125385.
InParanoidP42083.
OMANSHGAST.

Family and domain databases

InterProIPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamPF00102. Y_phosphatase. 1 hit.
[Graphical view]
SMARTSM00194. PTPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. False negative.
PS50056. TYR_PHOSPHATASE_2. False negative.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio890662.

Entry information

Entry nameYKCA_CAEEL
AccessionPrimary (citable) accession number: P42083
Secondary accession number(s): Q2V4X3
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: May 2, 2006
Last modified: May 1, 2013
This is version 92 of the entry and version 3 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programCaenorhabditis annotation project

Relevant documents

Caenorhabditis elegans

Caenorhabditis elegans: entries, gene names and cross-references to WormBase

SIMILARITY comments

Index of protein domains and families

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