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Protein

Oligopeptide transport ATP-binding protein AppD

Gene

appD

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for energy coupling to the transport system.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi41 – 48ATPPROSITE-ProRule annotation8

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCompetence, Peptide transport, Protein transport, Sporulation, Transport
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBSUB:BSU11360-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.20. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Oligopeptide transport ATP-binding protein AppD
Gene namesi
Name:appD
Ordered Locus Names:BSU11360
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000919311 – 328Oligopeptide transport ATP-binding protein AppDAdd BLAST328

Proteomic databases

PaxDbiP42064.

Interactioni

Protein-protein interaction databases

STRINGi224308.Bsubs1_010100006276.

Structurei

3D structure databases

ProteinModelPortaliP42064.
SMRiP42064.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 256ABC transporterPROSITE-ProRule annotationAdd BLAST252

Sequence similaritiesi

Belongs to the ABC transporter superfamily.Curated

Phylogenomic databases

eggNOGiENOG4105C3U. Bacteria.
COG0444. LUCA.
InParanoidiP42064.
KOiK02031.
OMAiEICDRVN.
PhylomeDBiP42064.

Family and domain databases

InterProiView protein in InterPro
IPR003593. AAA+_ATPase.
IPR003439. ABC_transporter-like.
IPR017871. ABC_transporter_CS.
IPR013563. Oligopep_ABC_C.
IPR027417. P-loop_NTPase.
PfamiView protein in Pfam
PF00005. ABC_tran. 1 hit.
PF08352. oligo_HPY. 1 hit.
SMARTiView protein in SMART
SM00382. AAA. 1 hit.
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR01727. oligo_HPY. 1 hit.
PROSITEiView protein in PROSITE
PS00211. ABC_TRANSPORTER_1. 1 hit.
PS50893. ABC_TRANSPORTER_2. 1 hit.

Sequencei

Sequence statusi: Complete.

P42064-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTLLEVNNL KTYFFRKKEP IPAVDGVDFH ISKGETVALV GESGSGKSIT
60 70 80 90 100
SLSIMGLVQS SGGKIMDGSI KLEDKDLTSF TENDYCKIRG NEVSMIFQEP
110 120 130 140 150
MTSLNPVLTI GEQITEVLIY HKNMKKKEAR QRAVELLQMV GFSRAEQIMK
160 170 180 190 200
EYPHRLSGGM RQRVMIAIAL SCNPKLLIAD EPTTALDVTI QAQVLELMKD
210 220 230 240 250
LCQKFNTSIL LITHDLGVVS EAADRVIVMY CGQVVENATV DDLFLEPLHP
260 270 280 290 300
YTEGLLTSIP VIDGEIDKLN AIKGSVPTPD NLPPGCRFAP RCPKAMDKCW
310 320
TNQPSLLTHK SGRTVRCFLY EEEGAEQS
Length:328
Mass (Da):36,311
Last modified:November 1, 1995 - v1
Checksum:iE4B87CD2B9D27F25
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20909 Genomic DNA. Translation: AAA62356.1.
AL009126 Genomic DNA. Translation: CAB12993.1.
PIRiI40543.
RefSeqiNP_389018.1. NC_000964.3.
WP_003232965.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12993; CAB12993; BSU11360.
GeneIDi936391.
KEGGibsu:BSU11360.
PATRICifig|224308.179.peg.1221.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.

Entry informationi

Entry nameiAPPD_BACSU
AccessioniPrimary (citable) accession number: P42064
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: June 7, 2017
This is version 122 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families