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Protein

Oligopeptide transport system permease protein AppB

Gene

appB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Biological processCompetence, Peptide transport, Protein transport, Sporulation, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU11390-MONOMER

Protein family/group databases

TCDBi3.A.1.5.20 the atp-binding cassette (abc) superfamily

Names & Taxonomyi

Protein namesi
Recommended name:
Oligopeptide transport system permease protein AppB
Gene namesi
Name:appB
Ordered Locus Names:BSU11390
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei10 – 30HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei100 – 120HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei138 – 158HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei177 – 197HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei240 – 260HelicalPROSITE-ProRule annotationAdd BLAST21
Transmembranei290 – 310HelicalPROSITE-ProRule annotationAdd BLAST21

GO - Cellular componenti

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000599491 – 316Oligopeptide transport system permease protein AppBAdd BLAST316

Proteomic databases

PRIDEiP42062

Structurei

3D structure databases

ProteinModelPortaliP42062
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 303ABC transmembrane type-1PROSITE-ProRule annotationAdd BLAST208

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000170243
InParanoidiP42062
KOiK02033
OMAiFADIPVM
PhylomeDBiP42062

Family and domain databases

CDDicd06261 TM_PBP2, 1 hit
Gene3Di1.10.3720.10, 1 hit
InterProiView protein in InterPro
IPR000515 MetI-like
IPR035906 MetI-like_sf
PfamiView protein in Pfam
PF00528 BPD_transp_1, 1 hit
SUPFAMiSSF161098 SSF161098, 1 hit
PROSITEiView protein in PROSITE
PS50928 ABC_TM1, 1 hit

Sequencei

Sequence statusi: Complete.

P42062-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYIIRRTL MSIPILLGIT ILSFVIMKAA PGDPMTLMMD PKISQADREQ
60 70 80 90 100
FIEKYGLNDP QYVQYLKWLG NMVQGDFGTS IVRKGTPVSE LIMARLPNTL
110 120 130 140 150
LLMLVSTILA LMISIPFGVL SAKRPYSKID YGITFTSFIG LAIPNFWFGL
160 170 180 190 200
ILIMVLSVNL GWFPTGGVET LNTEFNIFDR IHHLILPAFV LATADMAGLT
210 220 230 240 250
RYTRSNMLDV LNQDYIRTAR AKGFKENRVL FKHGLRNALL PVITIFGLMI
260 270 280 290 300
PSFIGGSVVV EQIFTWPGLG KLFVDSAFQR DYPVIMAMTV ISAVLVVVGN
310
LIADILYAIV DPRIEY
Length:316
Mass (Da):35,278
Last modified:June 16, 2009 - v2
Checksum:i90F879338D2B6253
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti281 – 284DYPV → TIIRI in AAA62359 (PubMed:7997159).Curated4

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20909 Genomic DNA Translation: AAA62359.1
AL009126 Genomic DNA Translation: CAB12996.2
PIRiI40546
RefSeqiNP_389021.2, NC_000964.3
WP_003245828.1, NZ_JNCM01000035.1

Genome annotation databases

EnsemblBacteriaiCAB12996; CAB12996; BSU11390
GeneIDi936400
KEGGibsu:BSU11390
PATRICifig|224308.179.peg.1225

Entry informationi

Entry nameiAPPB_BACSU
AccessioniPrimary (citable) accession number: P42062
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 16, 2009
Last modified: May 23, 2018
This is version 111 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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