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Protein

Oligopeptide transport system permease protein AppB

Gene

appB

Organism
Bacillus subtilis (strain 168)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

This protein is a component of an oligopeptide permease, a binding protein-dependent transport system. This APP system can completely substitute for the OPP system in both sporulation and genetic competence, though, unlike OPP, is incapable of transporting tripeptides. Probably responsible for the translocation of the substrate across the membrane (By similarity).By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Competence, Peptide transport, Protein transport, Sporulation, Transport

Enzyme and pathway databases

BioCyciBSUB:BSU11390-MONOMER.
RETL1328306-WGS:GSTH-4931-MONOMER.
RETL1328306-WGS:GSTH-6969-MONOMER.

Protein family/group databases

TCDBi3.A.1.5.20. the atp-binding cassette (abc) superfamily.

Names & Taxonomyi

Protein namesi
Recommended name:
Oligopeptide transport system permease protein AppB
Gene namesi
Name:appB
Ordered Locus Names:BSU11390
OrganismiBacillus subtilis (strain 168)
Taxonomic identifieri224308 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillus
Proteomesi
  • UP000001570 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei10 – 3021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei100 – 12021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei138 – 15821HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei177 – 19721HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei240 – 26021HelicalPROSITE-ProRule annotationAdd
BLAST
Transmembranei290 – 31021HelicalPROSITE-ProRule annotationAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 316316Oligopeptide transport system permease protein AppBPRO_0000059949Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP42062.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini96 – 303208ABC transmembrane type-1PROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 ABC transmembrane type-1 domain.PROSITE-ProRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000170243.
InParanoidiP42062.
KOiK02033.
OMAiITRYTRS.
PhylomeDBiP42062.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42062-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAAYIIRRTL MSIPILLGIT ILSFVIMKAA PGDPMTLMMD PKISQADREQ
60 70 80 90 100
FIEKYGLNDP QYVQYLKWLG NMVQGDFGTS IVRKGTPVSE LIMARLPNTL
110 120 130 140 150
LLMLVSTILA LMISIPFGVL SAKRPYSKID YGITFTSFIG LAIPNFWFGL
160 170 180 190 200
ILIMVLSVNL GWFPTGGVET LNTEFNIFDR IHHLILPAFV LATADMAGLT
210 220 230 240 250
RYTRSNMLDV LNQDYIRTAR AKGFKENRVL FKHGLRNALL PVITIFGLMI
260 270 280 290 300
PSFIGGSVVV EQIFTWPGLG KLFVDSAFQR DYPVIMAMTV ISAVLVVVGN
310
LIADILYAIV DPRIEY
Length:316
Mass (Da):35,278
Last modified:June 16, 2009 - v2
Checksum:i90F879338D2B6253
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti281 – 2844DYPV → TIIRI in AAA62359 (PubMed:7997159).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20909 Genomic DNA. Translation: AAA62359.1.
AL009126 Genomic DNA. Translation: CAB12996.2.
PIRiI40546.
RefSeqiNP_389021.2. NC_000964.3.
WP_003245828.1. NZ_JNCM01000035.1.

Genome annotation databases

EnsemblBacteriaiCAB12996; CAB12996; BSU11390.
GeneIDi936400.
KEGGibsu:BSU11390.
PATRICi18973993. VBIBacSub10457_1190.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20909 Genomic DNA. Translation: AAA62359.1.
AL009126 Genomic DNA. Translation: CAB12996.2.
PIRiI40546.
RefSeqiNP_389021.2. NC_000964.3.
WP_003245828.1. NZ_JNCM01000035.1.

3D structure databases

ProteinModelPortaliP42062.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

TCDBi3.A.1.5.20. the atp-binding cassette (abc) superfamily.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAB12996; CAB12996; BSU11390.
GeneIDi936400.
KEGGibsu:BSU11390.
PATRICi18973993. VBIBacSub10457_1190.

Phylogenomic databases

HOGENOMiHOG000170243.
InParanoidiP42062.
KOiK02033.
OMAiITRYTRS.
PhylomeDBiP42062.

Enzyme and pathway databases

BioCyciBSUB:BSU11390-MONOMER.
RETL1328306-WGS:GSTH-4931-MONOMER.
RETL1328306-WGS:GSTH-6969-MONOMER.

Family and domain databases

CDDicd06261. TM_PBP2. 1 hit.
Gene3Di1.10.3720.10. 1 hit.
InterProiIPR000515. MetI-like.
[Graphical view]
PfamiPF00528. BPD_transp_1. 1 hit.
[Graphical view]
SUPFAMiSSF161098. SSF161098. 1 hit.
PROSITEiPS50928. ABC_TM1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAPPB_BACSU
AccessioniPrimary (citable) accession number: P42062
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: June 16, 2009
Last modified: September 7, 2016
This is version 104 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Bacillus subtilis
    Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.