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Protein

Minor allergen Alt a 7

Gene

ALTA7

Organism
Alternaria alternata (Alternaria rot fungus) (Torula alternata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. FMN binding Source: InterPro
  2. oxidoreductase activity Source: InterPro

GO - Biological processi

  1. negative regulation of transcription, DNA-templated Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Minor allergen Alt a 7
Alternative name(s):
Allergen Alt a VII
Allergen: Alt a 7
Gene namesi
Name:ALTA7
OrganismiAlternaria alternata (Alternaria rot fungus) (Torula alternata)
Taxonomic identifieri5599 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaeAlternariaAlternaria alternata group

Subcellular locationi

Cytoplasm Curated

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

Pathology & Biotechi

Allergenic propertiesi

Causes an allergic reaction in human.

Keywords - Diseasei

Allergen

Protein family/group databases

Allergomei21. Alt a 7.
3064. Alt a 7.0101.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204Minor allergen Alt a 7PRO_0000200764Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP42058.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini5 – 195191Flavodoxin-likePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the WrbA family.Curated
Contains 1 flavodoxin-like domain.PROSITE-ProRule annotation

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P42058-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAPKIAIVYY SMYGHIKKMA DAELKGIQEA GGDAKLFQVA ETLPQEVLDK
60 70 80 90 100
MYAPPKDSSV PVLEDPAVLE EFDGILFGIP TRYGNFPAQF KTFWDKTGKQ
110 120 130 140 150
WQQGAFWGKY AGVFVSTGTL GGGQETTAIT SMSTLVDHGF IYVPLGYKTA
160 170 180 190 200
FSMLANLDEV HGGSPWGAGT FSAGDGSRQP SELELNIAQA QGKAFYEAVA

KAHQ
Length:204
Mass (Da):22,056
Last modified:October 31, 1995 - v1
Checksum:i9CB019A8531B80CB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78225 mRNA. Translation: CAA55069.1.
PIRiS43111.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78225 mRNA. Translation: CAA55069.1.
PIRiS43111.

3D structure databases

ProteinModelPortaliP42058.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

Allergomei21. Alt a 7.
3064. Alt a 7.0101.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

Gene3Di3.40.50.360. 1 hit.
InterProiIPR008254. Flavodoxin/NO_synth.
IPR029039. Flavoprotein-like.
IPR010089. Flavoprotein_WrbA.
[Graphical view]
PfamiPF00258. Flavodoxin_1. 1 hit.
[Graphical view]
SUPFAMiSSF52218. SSF52218. 1 hit.
TIGRFAMsiTIGR01755. flav_wrbA. 1 hit.
PROSITEiPS50902. FLAVODOXIN_LIKE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum."
    Achatz G., Oberkofler H., Lechenauer E., Simon-Nobbe B., Unger A., Kandler D., Ebner C., Prillinger H., Kraft D., Breitenbach M.
    Mol. Immunol. 32:213-227(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: 08-0203-Berlin.

Entry informationi

Entry nameiALTA7_ALTAL
AccessioniPrimary (citable) accession number: P42058
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 1995
Last sequence update: October 31, 1995
Last modified: January 6, 2015
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. Allergens
    Nomenclature of allergens and list of entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.