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P42037 (RLA2_ALTAL) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 60. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
60S acidic ribosomal protein P2
Alternative name(s):
Allergen Alt a 6
Allergen Alt a VI
Minor allergen Alt a 5
Allergen=Alt a 5
Gene names
Name:ALTA5
Synonyms:ALTA6
OrganismAlternaria alternata (Alternaria rot fungus) (Torula alternata)
Taxonomic identifier5599 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaDothideomycetesPleosporomycetidaePleosporalesPleosporineaePleosporaceaeAlternariaAlternaria alternata group

Protein attributes

Sequence length113 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Plays an important role in the elongation step of protein synthesis. HAMAP-Rule MF_01478

Subunit structure

P1 and P2 exist as dimers at the large ribosomal subunit.

Allergenic properties

Causes an allergic reaction in human. Ref.1

Sequence similarities

Belongs to the ribosomal protein L12P family.

Ontologies

Keywords
   DiseaseAllergen
   Molecular functionRibonucleoprotein
Ribosomal protein
   PTMPhosphoprotein
Gene Ontology (GO)
   Biological_processtranslational elongation

Inferred from electronic annotation. Source: InterPro

   Cellular_componentribosome

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionstructural constituent of ribosome

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 11311360S acidic ribosomal protein P2 HAMAP-Rule MF_01478
PRO_0000157672

Amino acid modifications

Modified residue1031Phosphoserine By similarity

Experimental info

Sequence conflict591S → P in AAB48041. Ref.2
Sequence conflict871Q → E in AAB48041. Ref.2

Sequences

Sequence LengthMass (Da)Tools
P42037 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 3A4B199E512D8099

FASTA11311,134
        10         20         30         40         50         60 
MKHLAAYLLL GLGGNTSPSA ADVKAVLESV GIEADSDRLD KLISELEGKD INELIASGSE 

        70         80         90        100        110 
KLASVPSGGA GGAAASGGAA AAGGSAQAEA APEAAKEEEK EESDEDMGFG LFD 

« Hide

References

[1]"Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum."
Achatz G., Oberkofler H., Lechenauer E., Simon-Nobbe B., Unger A., Kandler D., Ebner C., Prillinger H., Kraft D., Breitenbach M.
Mol. Immunol. 32:213-227(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGEN.
Strain: 08-0203-Berlin.
[2]"Molecular cloning of IgE-binding fragments of Alternaria alternata allergens."
De Vouge M.W., Thaker A.J., Zhang L., Muradia G., Rode H., Vijay H.M.
Int. Arch. Allergy Immunol. 116:261-268(1998) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X78222 mRNA. Translation: CAA55066.1.
U87806 mRNA. Translation: AAB48041.1.
PIRS43109.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protein family/group databases

Allergome20. Alt a 5.
3062. Alt a 5.0101.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

HAMAPMF_01478. Ribosomal_L12_arch.
InterProIPR001813. Ribosomal_L10/L12.
IPR027534. Ribosomal_L12.
[Graphical view]
PfamPF00428. Ribosomal_60s. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameRLA2_ALTAL
AccessionPrimary (citable) accession number: P42037
Secondary accession number(s): P78982
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 60 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Ribosomal proteins

Ribosomal proteins families and list of entries

Allergens

Nomenclature of allergens and list of entries