Reviewed,
UniProtKB/Swiss-Prot P42037 (RLA2_ALTAL)
Last modified
June 16, 2009.
Version 48.
History...
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90%,
50% identity |
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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents
Names and origin
| Protein names | Recommended name: 60S acidic ribosomal protein P2 Alternative name(s): Minor allergen Alt a 5 Allergen Alt a 6 Allergen Alt a VI Allergen=Alt a 5 | ||||
| Gene names |
| ||||
| Organism | Alternaria alternata (Alternaria rot fungus) | ||||
| Taxonomic identifier | 5599 [NCBI] | ||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Pezizomycotina › Dothideomycetes › Pleosporomycetidae › Pleosporales › Pleosporaceae › mitosporic Pleosporaceae › Alternaria › Alternaria alternata group |
Protein attributes
| Sequence length | 113 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Plays an important role in the elongation step of protein synthesis. |
| Subunit structure | P1 and P2 exist as dimers at the large ribosomal subunit. |
| Allergenic properties | Causes an allergic reaction in human. Ref.1 |
| Sequence similarities | Belongs to the ribosomal protein L12P family. |
Ontologies
| Keywords | |
|---|---|
| Disease | Allergen |
| Molecular function | Ribonucleoprotein Ribosomal protein |
| PTM | Phosphoprotein |
| Gene Ontology (GO) | |
| Biological process | translational elongation Inferred from electronic annotation. Source: InterPro |
| Cellular component | ribosome Inferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | structural constituent of ribosome Inferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 113 | 113 | 60S acidic ribosomal protein P2 | PRO_0000157672 | |||||
Amino acid modifications | |||||||||
| Modified residue | 103 | 1 | Phosphoserine By similarity | ||||||
Experimental info | |||||||||
| Sequence conflict | 59 | 1 | S → P in AAB48041. Ref.2 | ||||||
| Sequence conflict | 87 | 1 | Q → E in AAB48041. Ref.2 | ||||||
Sequences
References
| [1] | "Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum." Achatz G., Oberkofler H., Lechenauer E., Simon-Nobbe B., Unger A., Kandler D., Ebner C., Prillinger H., Kraft D., Breitenbach M. Mol. Immunol. 32:213-227(1995) [PubMed: 7898496] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA], ALLERGENICITY. Strain: 08-0203-Berlin. |
| [2] | "Molecular cloning of IgE-binding fragments of Alternaria alternata allergens." De Vouge M.W., Thaker A.J., Zhang L., Muradia G., Rode H., Vijay H.M. Int. Arch. Allergy Immunol. 116:261-268(1998) [PubMed: 9693275] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. |
Cross-references
Sequence databases | |
|---|---|
| X78222 mRNA. Translation: CAA55066.1. U87806 mRNA. Translation: AAB48041.1. | |
| PIR | S43109. |
3D structure databases | |
| ModBase | Search... |
Family and domain databases | |
| InterPro | IPR001813. Ribosomal_60S. [Graphical view] |
| Pfam | PF00428. Ribosomal_60s. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | RLA2_ALTAL | ||||||||
| Accession | Primary (citable) accession number: P42037 Secondary accession number(s): P78982 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| Allergens Nomenclature of allergens and list of entries |
| Ribosomal proteins Ribosomal proteins families and list of entries |
| SIMILARITY comments Index of protein domains and families |

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