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Protein

Ras-like GTP-binding protein RYL1

Gene

RYL1

Organism
Yarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Protein transport. Probably involved in vesicular traffic (By similarity).By similarity

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi18 – 25GTPBy similarity8
Nucleotide bindingi66 – 70GTPBy similarity5
Nucleotide bindingi124 – 127GTPBy similarity4

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Ras-like GTP-binding protein RYL1
Gene namesi
Name:RYL1
Ordered Locus Names:YALI0E23067g
OrganismiYarrowia lipolytica (strain CLIB 122 / E 150) (Yeast) (Candida lipolytica)
Taxonomic identifieri284591 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDipodascaceaeYarrowia
Proteomesi
  • UP000001300 Componenti: Chromosome E

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001213161 – 203Ras-like GTP-binding protein RYL1Add BLAST203

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Lipidationi202S-geranylgeranyl cysteineBy similarity1
Lipidationi203S-geranylgeranyl cysteineBy similarity1

Keywords - PTMi

Lipoprotein, Prenylation

Proteomic databases

PRIDEiP41924.

Structurei

3D structure databases

ProteinModelPortaliP41924.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi40 – 48Effector regionCurated9

Sequence similaritiesi

Belongs to the small GTPase superfamily. Rab family.Curated

Phylogenomic databases

HOGENOMiHOG000233968.
InParanoidiP41924.
KOiK07901.
OMAiTNWIRNI.
OrthoDBiEOG092C5MDH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P41924-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSHSQRTYDL LIKLLLIGDS GVGKSCLLLR FCEDQFTPSF ITTIGIDFKI
60 70 80 90 100
RTIDIGNQRV KLQVWDTAGQ ERFRTITTAY YRGAMGILLV YDVTDEKSFN
110 120 130 140 150
NIENWYQNVQ SYANEGVELI LVGNKCDLDE KRVVSTEQGQ ALADKFGIPF
160 170 180 190 200
LEASSKTNIN VEECFYSVAT RIRDTVAKTK GNESGSGGIN IAEGEENSAS

KCC
Length:203
Mass (Da):22,608
Last modified:November 1, 1995 - v1
Checksum:i9559AFCEEBEE7887
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06969 Genomic DNA. Translation: AAA35245.1.
CR382131 Genomic DNA. Translation: CAG79891.1.
PIRiS51495.
RefSeqiXP_504292.1. XM_504292.1.

Genome annotation databases

EnsemblFungiiCAG79891; CAG79891; YALI0_E23067g.
GeneIDi2911588.
KEGGiyli:YALI0E23067g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L06969 Genomic DNA. Translation: AAA35245.1.
CR382131 Genomic DNA. Translation: CAG79891.1.
PIRiS51495.
RefSeqiXP_504292.1. XM_504292.1.

3D structure databases

ProteinModelPortaliP41924.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiP41924.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG79891; CAG79891; YALI0_E23067g.
GeneIDi2911588.
KEGGiyli:YALI0E23067g.

Phylogenomic databases

HOGENOMiHOG000233968.
InParanoidiP41924.
KOiK07901.
OMAiTNWIRNI.
OrthoDBiEOG092C5MDH.

Family and domain databases

Gene3Di3.40.50.300. 1 hit.
InterProiIPR027417. P-loop_NTPase.
IPR005225. Small_GTP-bd_dom.
IPR001806. Small_GTPase.
[Graphical view]
PfamiPF00071. Ras. 1 hit.
[Graphical view]
SUPFAMiSSF52540. SSF52540. 1 hit.
TIGRFAMsiTIGR00231. small_GTP. 1 hit.
PROSITEiPS51419. RAB. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRYL1_YARLI
AccessioniPrimary (citable) accession number: P41924
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.