P41831 (KPR1_SCHPO) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 29, 2013.
Version 90.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Ribose-phosphate pyrophosphokinase 1 EC=2.7.6.1 Alternative name(s): Phosphoribosyl pyrophosphate synthase 1 | ||
| Gene names |
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| Organism | Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) [Reference proteome] | ||
| Taxonomic identifier | 284812 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces › ![]() |
Protein attributes
| Sequence length | 409 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | 5-phosphoribose 1-diphosphate synthase involved in nucleotide, histidine, and tryptophan biosynthesis. Active in heteromultimeric complexes with other 5-phosphoribose 1-diphosphate synthases By similarity. |
| Catalytic activity | ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate. |
| Pathway | |
| Subcellular location | |
| Sequence similarities | Belongs to the ribose-phosphate pyrophosphokinase family. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 409 | 409 | Ribose-phosphate pyrophosphokinase 1 | PRO_0000141091 | |||||
Sites | |||||||||
| Metal binding | 128 | 1 | Magnesium Potential | ||||||
| Metal binding | 130 | 1 | Magnesium Potential | ||||||
| Metal binding | 143 | 1 | Magnesium Potential | ||||||
Amino acid modifications | |||||||||
| Modified residue | 199 | 1 | Phosphoserine By similarity | ||||||
Sequences
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References
| « Hide 'large scale' references | |
| [1] | Hilti N. Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 972 / ATCC 24843. |
| [2] | "The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. Nurse P.Nature 415:871-880(2002) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 972 / ATCC 24843. |
| [3] | "ORFeome cloning and global analysis of protein localization in the fission yeast Schizosaccharomyces pombe." Matsuyama A., Arai R., Yashiroda Y., Shirai A., Kamata A., Sekido S., Kobayashi Y., Hashimoto A., Hamamoto M., Hiraoka Y., Horinouchi S., Yoshida M. Nat. Biotechnol. 24:841-847(2006) [PubMed] [Europe PMC] [Abstract] Cited for: SUBCELLULAR LOCATION [LARGE SCALE ANALYSIS]. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | X83866 Genomic DNA. Translation: CAA58747.1. CU329670 Genomic DNA. Translation: CAB11484.1. |
| PIR | S51326. |
| RefSeq | NP_593826.1. NM_001019255.2. |
3D structure databases | |
| ProteinModelPortal | P41831. |
| ModBase | Search... |
Protein-protein interaction databases | |
| MINT | MINT-4690132. |
| STRING | 4896.SPAC4A8.14-1. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblFungi | SPAC4A8.14.1; SPAC4A8.14.1:pep; SPAC4A8.14. |
| GeneID | 2543525. |
| KEGG | spo:SPAC4A8.14. |
Organism-specific databases | |
| PomBase | SPAC4A8.14. |
Phylogenomic databases | |
| eggNOG | COG0462. |
| HOGENOM | HOG000210451. |
| KO | K00948. |
| OMA | VTNTYPI. |
| OrthoDB | EOG47WRX7. |
Enzyme and pathway databases | |
| UniPathway | UPA00087; UER00172. |
Family and domain databases | |
| InterPro | IPR000842. PRib_PP_synth_CS. IPR005946. Rib-P_diPkinase. [Graphical view] |
| TIGRFAMs | TIGR01251. ribP_PPkin. 1 hit. |
| PROSITE | PS00114. PRPP_SYNTHASE. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other | |
| NextBio | 20804535. |
Entry information
| Entry name | KPR1_SCHPO | ||||||||
| Accession | Primary (citable) accession number: P41831 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Fungal Protein Annotation Program | ||||||||
Relevant documents
| Schizosaccharomyces pombe Schizosaccharomyces pombe: entries and gene names |
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
