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Protein

Protein GLC8

Gene

GLC8

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Modulator of GLC7 type-1 protein phosphatase.

Miscellaneous

Present with 3440 molecules/cell in log phase SD medium.1 Publication

GO - Molecular functioni

  • enzyme activator activity Source: SGD
  • protein phosphatase inhibitor activity Source: GO_Central

GO - Biological processi

  • chromosome segregation Source: SGD
  • glycogen biosynthetic process Source: SGD
  • regulation of phosphoprotein phosphatase activity Source: GO_Central
  • regulation of signal transduction Source: InterPro

Keywordsi

Biological processCarbohydrate metabolism, Glycogen metabolism

Enzyme and pathway databases

BioCyciYEAST:G3O-32975-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Protein GLC8
Gene namesi
Name:GLC8
Ordered Locus Names:YMR311C
ORF Names:YM9924.03C
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XIII

Organism-specific databases

EuPathDBiFungiDB:YMR311C
SGDiS000004928 GLC8

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000715171 – 229Protein GLC8Add BLAST229

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei12PhosphoserineCombined sources1
Modified residuei118Phosphothreonine; by PHO851 Publication1
Modified residuei158PhosphoserineCombined sources1
Modified residuei184PhosphoserineCombined sources1

Post-translational modificationi

Phosphorylated by the cyclin-CDKs PCL6-PHO85 and PCL7-PHO85. Phosphorylation of Thr-118 inactivates GLC8.1 Publication

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP41818
PaxDbiP41818
PRIDEiP41818

PTM databases

iPTMnetiP41818

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
GLC7P325985EBI-7629,EBI-13715

Protein-protein interaction databases

BioGridi35491, 119 interactors
DIPiDIP-2349N
ELMiP41818
IntActiP41818, 4 interactors
MINTiP41818
STRINGi4932.YMR311C

Structurei

3D structure databases

ProteinModelPortaliP41818
SMRiP41818
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000000770
InParanoidiP41818
KOiK16833
OMAiENDEDSP
OrthoDBiEOG092C5H3F

Family and domain databases

InterProiView protein in InterPro
IPR007062 PPI-2
PANTHERiPTHR12398 PTHR12398, 1 hit
PfamiView protein in Pfam
PF04979 IPP-2, 1 hit

Sequencei

Sequence statusi: Complete.

P41818-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGGILKNPLA LSPEQLAQQD PETLEEFRRQ VYENTQKNAK LTSHKRNIPG
60 70 80 90 100
LDNTKEEGEI IGTSSTFLPK DTLSLKHEQD MLAKMTPEER VQWNQRNLAE
110 120 130 140 150
NEITKKQFQD IHIDEPKTPY QGAVDPHGEY YRVDDDEDED NSDKKPCQVA
160 170 180 190 200
NDDIDDLSLG EPEFEIKENK QPDFETNDEN DEDSPEARHK KFEEMRKKHY
210 220
DVRAIFNKKS REALKDEDED EDDSTTKEP
Length:229
Mass (Da):26,649
Last modified:November 1, 1995 - v1
Checksum:iD4017CA8B3B089C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L22000 Genomic DNA Translation: AAA53673.1
Z54141 Genomic DNA Translation: CAA90829.1
AY557977 Genomic DNA Translation: AAS56303.1
BK006946 Genomic DNA Translation: DAA10212.1
PIRiS47859
RefSeqiNP_014042.1, NM_001182822.1

Genome annotation databases

EnsemblFungiiYMR311C; YMR311C; YMR311C
GeneIDi855359
KEGGisce:YMR311C

Similar proteinsi

Entry informationi

Entry nameiGLC8_YEAST
AccessioniPrimary (citable) accession number: P41818
Secondary accession number(s): D6W0D8
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: May 23, 2018
This is version 148 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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