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P41775 (COX3_MYTED) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismMytilus edulis (Blue mussel)
Taxonomic identifier6550 [NCBI]
Taxonomic lineageEukaryotaMetazoaLophotrochozoaMolluscaBivalviaPteriomorphiaMytiloidaMytiloideaMytilidaeMytilinaeMytilus

Protein attributes

Sequence length265 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 265265Cytochrome c oxidase subunit 3
PRO_0000183810

Regions

Transmembrane16 – 3621Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane83 – 10321Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane198 – 21821Helical; Potential
Transmembrane241 – 26121Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
P41775 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 8427728B6D994DF7

FASTA26530,792
        10         20         30         40         50         60 
MNRNPYSRYY VPGPSPWPFF VAISANGMAV GLILWLHRTP SFLLMGMSLV CMLLSTFSWW 

        70         80         90        100        110        120 
RDLIREGDIG FHTRFVIKSF RDCVALFILS EVMFFFTFFW TFFHNALSPS CELGMRWPPP 

       130        140        150        160        170        180 
GIRTPNPSST SLFETGLLIS SGLFVTQAHK SMRLKDYDVG PFIGLVVTIV CGTVFFLVQL 

       190        200        210        220        230        240 
REYYWNSYTI ADSVYGSVFY LLTGFHGMHV VVGTIWLMVS LVRLWRGEFS SQRHFGFEAC 

       250        260 
IWYWHFVDVV WVALWCLVYV WFGGW 

« Hide

References

[1]"A novel mitochondrial genome organization for the blue mussel, Mytilus edulis."
Hoffmann R.J., Boore J.L., Brown W.M.
Genetics 131:397-412(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]"Complete sequences of the highly rearranged molluscan mitochondrial genomes of the scaphopod Graptacme eborea and the bivalve Mytilus edulis."
Boore J.L., Medina M., Rosenberg L.A.
Mol. Biol. Evol. 21:1492-1503(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AY484747 Genomic DNA. Translation: AAA31906.3.
PIRS66600.
RefSeqYP_073340.1. NC_006161.1.

3D structure databases

ProteinModelPortalP41775.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2960260.

Organism-specific databases

CTD4514.

Phylogenomic databases

ProtClustDBMTH00141.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_MYTED
AccessionPrimary (citable) accession number: P41775
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: April 16, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families