Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P41762

- PGKG_TRYCO

UniProt

P41762 - PGKG_TRYCO

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Phosphoglycerate kinase, glycosomal

Gene

56PGK

Organism
Trypanosoma congolense
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei48 – 481SubstrateBy similarity
Binding sitei224 – 2241SubstrateBy similarity
Binding sitei261 – 2611SubstrateBy similarity
Binding sitei312 – 3121ATPBy similarity
Binding sitei434 – 4341ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi464 – 4674ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase, glycosomal (EC:2.7.2.3)
Gene namesi
Name:56PGK
OrganismiTrypanosoma congolense
Taxonomic identifieri5692 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosomaNannomonas

Subcellular locationi

GO - Cellular componenti

  1. glycosome Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Glycosome, Peroxisome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 509509Phosphoglycerate kinase, glycosomalPRO_0000145868Add
BLAST

Interactioni

Subunit structurei

Monomer.

Structurei

3D structure databases

ProteinModelPortaliP41762.
SMRiP41762. Positions 14-508.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni33 – 353Substrate bindingBy similarity
Regioni71 – 744Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Family and domain databases

Gene3Di3.40.50.1260. 2 hits.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR027250. Pgk_euglenozoa.
IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PIRSF500126. Pgk_euglenozoa. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 2 hits.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P41762-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSHVTGVTSN IRIKKTIDDI WPLTAKRVLV RVDFNVPIQN GHITNDYRIR
60 70 80 90 100
ATIPTIQRII DQGGICILLS HLGRPAGISM TTAVRDVRRR YHEAHFHDNK
110 120 130 140 150
GKTAFFSVLP PEEKIKILAQ SSLREEATHI MPGVKSGKTI LFARLPEDEK
160 170 180 190 200
KQLLMQYLDE KKDNGLPQLS VSAGYEEQYS LRPVAVRLAE LLGQHVYFAH
210 220 230 240 250
DCMDAKMELS RLKRGNVMLL ENVRFYREED SKKEEEREAM AKVLASYGDI
260 270 280 290 300
FVSDAFGTAH RDSATMTGIP KVLGHGAAGY LMEKEISYFS KVLGNPPRPL
310 320 330 340 350
VAIVGGSKVS DKIQLLDNML QRIDYLLIGG AMAYTFLKAQ GHRIGTSMCE
360 370 380 390 400
EDRLDLARSL LKKAEDRKVQ VLLPVDHVCH TEFKAVDTPV VTADADIPDG
410 420 430 440 450
HMALDIGPKT IANYVETIGK CKSAIWNGPM GVFEMTPYSK GTFAVAKAMG
460 470 480 490 500
DCTQKNGLMS IIGGGDSASA AEQSGEATRM SHVSTGGGAS LELLEGKTLP

GVAILDDKE
Length:509
Mass (Da):55,963
Last modified:November 1, 1995 - v1
Checksum:iEA3FFD44B9426B3A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37337 Genomic DNA. Translation: AAC37221.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L37337 Genomic DNA. Translation: AAC37221.1 .

3D structure databases

ProteinModelPortali P41762.
SMRi P41762. Positions 14-508.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 2 hits.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR027250. Pgk_euglenozoa.
IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PIRSF500126. Pgk_euglenozoa. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 2 hits.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Three genes and two isozymes: gene conversion and the compartmentalization and expression of the phosphoglycerate kinases of Trypanosoma (Nannomonas) congolense."
    Parker H.L., Hill T., Alexander K.A., Murphy N.B., Fish W.R., Parsons M.
    Mol. Biochem. Parasitol. 69:269-279(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: IL3000.

Entry informationi

Entry nameiPGKG_TRYCO
AccessioniPrimary (citable) accession number: P41762
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3