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P41757

- PGK_CANMA

UniProt

P41757 - PGK_CANMA

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Protein

Phosphoglycerate kinase

Gene

PGK1

Organism
Candida maltosa (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei39 – 391SubstrateBy similarity
Binding sitei122 – 1221SubstrateBy similarity
Binding sitei170 – 1701SubstrateBy similarity
Binding sitei219 – 2191ATPBy similarity
Binding sitei312 – 3121ATP; via carbonyl oxygenBy similarity
Binding sitei343 – 3431ATPBy similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi372 – 3754ATPBy similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoglycerate kinase activity Source: UniProtKB-EC

GO - Biological processi

  1. glycolytic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Transferase

Keywords - Biological processi

Glycolysis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

UniPathwayiUPA00109; UER00185.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinase (EC:2.7.2.3)
Gene namesi
Name:PGK1
OrganismiCandida maltosa (Yeast)
Taxonomic identifieri5479 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesDebaryomycetaceaeCandida/Lodderomyces cladeCandida

Subcellular locationi

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 417417Phosphoglycerate kinasePRO_0000145878Add
BLAST

Proteomic databases

PRIDEiP41757.

Interactioni

Subunit structurei

Monomer.By similarity

Structurei

3D structure databases

ProteinModelPortaliP41757.
SMRiP41757. Positions 2-416.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni24 – 263Substrate bindingBy similarity
Regioni63 – 664Substrate bindingBy similarity

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.Curated

Family and domain databases

Gene3Di3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase.
InterProiIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 1 hit.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 1 hit.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P41757-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSLSNKLSVK DLNVTGKRVF IRVDFNVPLD GKTITNNQRI VAALPTIKYV
60 70 80 90 100
EEQKPKCIIL ASHLGRPNGE RNEKYSLAPV AAELEKLLGQ KVTFLDDCVG
110 120 130 140 150
PEVTKAVDSA TEGQIFLLEN LRFHIEEEGS AKDKDGKKTK ADPEAVKKFR
160 170 180 190 200
EQLTSLADVY VNDAFGTAHR AHSSMVGLEV PERAAGFLMS KELEYFAKAL
210 220 230 240 250
ENPQRPFLAI LGGAKVSDKI QLIDNLLDKV DMLIVGGGMA FTFKKVLNNM
260 270 280 290 300
PIGDSLFDEA GAKNVENLVA KAKKNNVELI LPVDFVTADK FDKDAEVSTA
310 320 330 340 350
DDVTGIPDKW MGLDCGPKSR KLFADAVAKA KTIVWNGPPG VFEFDKFAEG
360 370 380 390 400
TKSLLDDAVK SAEVGNIVII GGGDTATVAK KYGVVDKLSH VSTGGGASLE
410
LLEGKELPGV TALSNKA
Length:417
Mass (Da):44,947
Last modified:November 1, 1995 - v1
Checksum:iCA22E3D2F3D1D8F1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12474 Genomic DNA. Translation: BAA02040.1.
PIRiS43525. JT0950.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D12474 Genomic DNA. Translation: BAA02040.1 .
PIRi S43525. JT0950.

3D structure databases

ProteinModelPortali P41757.
SMRi P41757. Positions 2-416.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi P41757.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00109 ; UER00185 .

Family and domain databases

Gene3Di 3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPi MF_00145. Phosphoglyc_kinase.
InterProi IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view ]
PANTHERi PTHR11406. PTHR11406. 1 hit.
Pfami PF00162. PGK. 1 hit.
[Graphical view ]
PIRSFi PIRSF000724. Pgk. 1 hit.
PRINTSi PR00477. PHGLYCKINASE.
SUPFAMi SSF53748. SSF53748. 1 hit.
PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Expression of an endogenous and a heterologous gene in Candida maltosa by using a promoter of a newly-isolated phosphoglycerate kinase (PGK) gene."
    Masuda Y., Park S.M., Ohkuma M., Ohta A., Takagi M.
    Curr. Genet. 25:412-417(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977.

Entry informationi

Entry nameiPGK_CANMA
AccessioniPrimary (citable) accession number: P41757
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 29, 2014
This is version 64 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3