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P41757

- PGK_CANMA

UniProt

P41757 - PGK_CANMA

Protein

Phosphoglycerate kinase

Gene

PGK1

Organism
Candida maltosa (Yeast)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 63 (01 Oct 2014)
      Sequence version 1 (01 Nov 1995)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei39 – 391SubstrateBy similarity
    Binding sitei122 – 1221SubstrateBy similarity
    Binding sitei170 – 1701SubstrateBy similarity
    Binding sitei219 – 2191ATPBy similarity
    Binding sitei312 – 3121ATP; via carbonyl oxygenBy similarity
    Binding sitei343 – 3431ATPBy similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi372 – 3754ATPBy similarity

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. phosphoglycerate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    Kinase, Transferase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00185.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Phosphoglycerate kinase (EC:2.7.2.3)
    Gene namesi
    Name:PGK1
    OrganismiCandida maltosa (Yeast)
    Taxonomic identifieri5479 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesmitosporic SaccharomycetalesCandida

    Subcellular locationi

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 417417Phosphoglycerate kinasePRO_0000145878Add
    BLAST

    Proteomic databases

    PRIDEiP41757.

    Interactioni

    Subunit structurei

    Monomer.By similarity

    Structurei

    3D structure databases

    ProteinModelPortaliP41757.
    SMRiP41757. Positions 2-416.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni24 – 263Substrate bindingBy similarity
    Regioni63 – 664Substrate bindingBy similarity

    Sequence similaritiesi

    Belongs to the phosphoglycerate kinase family.Curated

    Family and domain databases

    Gene3Di3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPiMF_00145. Phosphoglyc_kinase.
    InterProiIPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view]
    PANTHERiPTHR11406. PTHR11406. 1 hit.
    PfamiPF00162. PGK. 1 hit.
    [Graphical view]
    PIRSFiPIRSF000724. Pgk. 1 hit.
    PRINTSiPR00477. PHGLYCKINASE.
    SUPFAMiSSF53748. SSF53748. 1 hit.
    PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P41757-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSLSNKLSVK DLNVTGKRVF IRVDFNVPLD GKTITNNQRI VAALPTIKYV    50
    EEQKPKCIIL ASHLGRPNGE RNEKYSLAPV AAELEKLLGQ KVTFLDDCVG 100
    PEVTKAVDSA TEGQIFLLEN LRFHIEEEGS AKDKDGKKTK ADPEAVKKFR 150
    EQLTSLADVY VNDAFGTAHR AHSSMVGLEV PERAAGFLMS KELEYFAKAL 200
    ENPQRPFLAI LGGAKVSDKI QLIDNLLDKV DMLIVGGGMA FTFKKVLNNM 250
    PIGDSLFDEA GAKNVENLVA KAKKNNVELI LPVDFVTADK FDKDAEVSTA 300
    DDVTGIPDKW MGLDCGPKSR KLFADAVAKA KTIVWNGPPG VFEFDKFAEG 350
    TKSLLDDAVK SAEVGNIVII GGGDTATVAK KYGVVDKLSH VSTGGGASLE 400
    LLEGKELPGV TALSNKA 417
    Length:417
    Mass (Da):44,947
    Last modified:November 1, 1995 - v1
    Checksum:iCA22E3D2F3D1D8F1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12474 Genomic DNA. Translation: BAA02040.1.
    PIRiS43525. JT0950.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    D12474 Genomic DNA. Translation: BAA02040.1 .
    PIRi S43525. JT0950.

    3D structure databases

    ProteinModelPortali P41757.
    SMRi P41757. Positions 2-416.
    ModBasei Search...
    MobiDBi Search...

    Proteomic databases

    PRIDEi P41757.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00185 .

    Family and domain databases

    Gene3Di 3.40.50.1260. 1 hit.
    3.40.50.1270. 1 hit.
    HAMAPi MF_00145. Phosphoglyc_kinase.
    InterProi IPR001576. Phosphoglycerate_kinase.
    IPR015901. Phosphoglycerate_kinase_C.
    IPR015911. Phosphoglycerate_kinase_CS.
    IPR015824. Phosphoglycerate_kinase_N.
    [Graphical view ]
    PANTHERi PTHR11406. PTHR11406. 1 hit.
    Pfami PF00162. PGK. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF000724. Pgk. 1 hit.
    PRINTSi PR00477. PHGLYCKINASE.
    SUPFAMi SSF53748. SSF53748. 1 hit.
    PROSITEi PS00111. PGLYCERATE_KINASE. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Expression of an endogenous and a heterologous gene in Candida maltosa by using a promoter of a newly-isolated phosphoglycerate kinase (PGK) gene."
      Masuda Y., Park S.M., Ohkuma M., Ohta A., Takagi M.
      Curr. Genet. 25:412-417(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 28140 / CBS 5611 / IAM 12247 / JCM 1504 / NBRC 1977.

    Entry informationi

    Entry nameiPGK_CANMA
    AccessioniPrimary (citable) accession number: P41757
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 1, 1995
    Last sequence update: November 1, 1995
    Last modified: October 1, 2014
    This is version 63 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3