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P41756 (PGK_ASPOR) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 76. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgkA
ORF Names:AO090038000395
OrganismAspergillus oryzae (strain ATCC 42149 / RIB 40) (Yellow koji mold) [Complete proteome]
Taxonomic identifier510516 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaPezizomycotinaEurotiomycetesEurotiomycetidaeEurotialesAspergillaceaeAspergillus

Protein attributes

Sequence length417 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 417417Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145875

Regions

Nucleotide binding373 – 3764ATP By similarity
Region24 – 263Substrate binding By similarity
Region64 – 674Substrate binding By similarity

Sites

Binding site401Substrate By similarity
Binding site1231Substrate By similarity
Binding site1711Substrate By similarity
Binding site2201ATP By similarity
Binding site3131ATP; via carbonyl oxygen By similarity
Binding site3441ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
P41756 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 6A25309DF5922A5A

FASTA41744,383
        10         20         30         40         50         60 
MSLSNKLAIT DVDLKDKRVL IRVDFNVPLD ADKKITNNQR IVGALPTIKY AIENGAKAVV 

        70         80         90        100        110        120 
LMSHLGRPDG KANPKYSLKP VATELEKLLS KSVIFAENCV GKETEEIVNK ATGGQIILLE 

       130        140        150        160        170        180 
NLRFHAEEEG SSKDAEGKKV KADKEKVEEF RKGLTALGDV YINDAFGTAH RAHSSMVGVD 

       190        200        210        220        230        240 
LPQKASGFLV KKELEYFAKA LESPQRPFLA ILGGAKVSDK IQLIDNLLPK VNSLIITGAM 

       250        260        270        280        290        300 
AFTFKKTLEN VKIGNSLFDE AGSKIVGDIV EKAKKNNVKI VLPVDYVTAD KFAADAKTGY 

       310        320        330        340        350        360 
ATDADGIPDG YMGLDVGEKS VELYKKTIAE AKTILWNGPP GVFELEPFAN ATKKTLDAAV 

       370        380        390        400        410 
AAAQSGSIVI IGGGDTATVA AKYGAEAKLS HVSTGGGASL ELLEGKVLPG VDALSSK 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
D28484 Genomic DNA. Translation: BAA05843.1.
AP007169 Genomic DNA. Translation: BAE64188.1.
RefSeqXP_001825321.1. XM_001825269.2.
XP_003190640.1. XM_003190592.1.

3D structure databases

ProteinModelPortalP41756.
SMRP41756. Positions 2-416.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5062.CADAORAP00008985.

Proteomic databases

PRIDEP41756.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiCADAORAT00009170; CADAORAP00008985; CADAORAG00009170.
GeneID5997416.
KEGGaor:AOR_1_654074.

Phylogenomic databases

eggNOGCOG0126.
HOGENOMHOG000227107.
KOK00927.
OMAGLDCGEK.
OrthoDBEOG71K6D7.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_ASPOR
AccessionPrimary (citable) accession number: P41756
Secondary accession number(s): Q2U2M7
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: February 19, 2014
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways