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Protein

Asparagine-rich zinc finger protein AZF1

Gene

AZF1

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Potential transcription factor; suppressor for a mitochondrial RNA polymerase mutant.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri593 – 61523C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri621 – 64323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri649 – 67123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri677 – 70226C2H2-type 4PROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

  • cellular response to carbohydrate stimulus Source: SGD
  • regulation of fungal-type cell wall organization Source: SGD
  • regulation of transcription from RNA polymerase II promoter Source: SGD
Complete GO annotation...

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding, Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-33642-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Asparagine-rich zinc finger protein AZF1
Gene namesi
Name:AZF1
Ordered Locus Names:YOR113W
ORF Names:O3244, YOR3244W
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XV

Organism-specific databases

EuPathDBiFungiDB:YOR113W.
SGDiS000005639. AZF1.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: SGD
  • nucleus Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 914914Asparagine-rich zinc finger protein AZF1PRO_0000046802Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei61 – 611PhosphoserineCombined sources
Modified residuei286 – 2861PhosphoserineCombined sources
Modified residuei325 – 3251PhosphoserineCombined sources

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP41696.

PTM databases

iPTMnetiP41696.

Interactioni

Protein-protein interaction databases

BioGridi34509. 64 interactions.
IntActiP41696. 10 interactions.
MINTiMINT-2493394.

Structurei

3D structure databases

ProteinModelPortaliP41696.
SMRiP41696. Positions 591-698.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Compositional biasi136 – 1438Poly-Gln
Compositional biasi146 – 1549Poly-Gln
Compositional biasi362 – 38120Poly-AsnAdd
BLAST
Compositional biasi856 – 8605Poly-Ser
Compositional biasi861 – 8688Poly-Asn

Sequence similaritiesi

Contains 4 C2H2-type zinc fingers.PROSITE-ProRule annotation

Zinc finger

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri593 – 61523C2H2-type 1PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri621 – 64323C2H2-type 2PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri649 – 67123C2H2-type 3PROSITE-ProRule annotationAdd
BLAST
Zinc fingeri677 – 70226C2H2-type 4PROSITE-ProRule annotationAdd
BLAST

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

GeneTreeiENSGT00840000130173.
InParanoidiP41696.
OMAiNPSENIP.
OrthoDBiEOG092C5UG7.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P41696-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPPTAQFMG PTQAGQNESQ NQSSGEAGEQ NQEHGQGPTP ILNQSQPASS
60 70 80 90 100
QPQHQQQRNE SISYYTNFNQ PRYSTDASIN SFLNISDNVP VTSTGGPSSG
110 120 130 140 150
GAYSNLPRLS TSSTHQPPDL SQIGRGFSIV NNLFPQQQQL QNQHRQQQQQ
160 170 180 190 200
QQQQSHQQPP FKTPSFSTGL TGSSSQYQFL PRNDNTSQPP SKRNSVYLGP
210 220 230 240 250
NDGPDFEFFS MQQSQQPQFQ PSSRRESNSM RPPLLIPAAT TKSQSNGTNN
260 270 280 290 300
SGNMNTNADY ESFFNTGTNN SNSNQNPYFL SSRNNSLKFN PEDFDFQFKR
310 320 330 340 350
RNSFVRGTLD HSSQNAFIPE SRLNSLSVNN KANGDPVADN VTNNMKGKSN
360 370 380 390 400
EVDNDDGNDS SNNNNNNNNN NNNENNNDNN NDNNDNSINS ATSTNIPNQE
410 420 430 440 450
DHSLASTDTT SNSRKDLKEI EQRLRKHLND EDNYSSAISR PLDKNDVIEG
460 470 480 490 500
SEGLNKHIDE SGMQPNIIKK RKKDDSTVYV KNEMPRTDPP MSKDNSTSAE
510 520 530 540 550
GAAMANFSGK EPPIPDISSV SDDATNLIGA TKVDQLMLII QARKKGFTEK
560 570 580 590 600
VNTTQDGDLL FNQTMDILPP KSELVGGVEK PKGTQNTRAV KKHECPYCHR
610 620 630 640 650
LFSQATHLEV HVRSHIGYKP FVCDYCGKRF TQGGNLRTHE RLHTGEKPYS
660 670 680 690 700
CDICDKKFSR KGNLAAHLVT HQKLKPFVCK LENCNKTFTQ LGNMKAHQNR
710 720 730 740 750
FHKETLNALT AKLAEMNPSE NIPLEERQLL EYFASIYKNS NRGIKGRGKG
760 770 780 790 800
VGTKKSTISS PENHPASTIL NPNTNANNAI ANDSENNGNP EGNIDSSSNS
810 820 830 840 850
NPGSHSMISP TQKDMGTLQS QFIQNNFNNS VNSSNPSNQP IINYNYTTLP
860 870 880 890 900
HSRLGSSSSS NTNNNNSNFS VGAAPGVLMA PTTNNDFSFN LDQSNDNERS
910
QQEQVRFKNI NYKS
Length:914
Mass (Da):101,170
Last modified:November 1, 1995 - v1
Checksum:iBA1898DAB68AD050
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z26253 Genomic DNA. Translation: CAA81212.1.
X90518 Genomic DNA. Translation: CAA62111.1.
X94335 Genomic DNA. Translation: CAA64033.1.
Z75021 Genomic DNA. Translation: CAA99311.1.
BK006948 Genomic DNA. Translation: DAA10888.1.
PIRiS46593.
RefSeqiNP_014756.3. NM_001183532.3.

Genome annotation databases

EnsemblFungiiYOR113W; YOR113W; YOR113W.
GeneIDi854280.
KEGGisce:YOR113W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z26253 Genomic DNA. Translation: CAA81212.1.
X90518 Genomic DNA. Translation: CAA62111.1.
X94335 Genomic DNA. Translation: CAA64033.1.
Z75021 Genomic DNA. Translation: CAA99311.1.
BK006948 Genomic DNA. Translation: DAA10888.1.
PIRiS46593.
RefSeqiNP_014756.3. NM_001183532.3.

3D structure databases

ProteinModelPortaliP41696.
SMRiP41696. Positions 591-698.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi34509. 64 interactions.
IntActiP41696. 10 interactions.
MINTiMINT-2493394.

PTM databases

iPTMnetiP41696.

Proteomic databases

MaxQBiP41696.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYOR113W; YOR113W; YOR113W.
GeneIDi854280.
KEGGisce:YOR113W.

Organism-specific databases

EuPathDBiFungiDB:YOR113W.
SGDiS000005639. AZF1.

Phylogenomic databases

GeneTreeiENSGT00840000130173.
InParanoidiP41696.
OMAiNPSENIP.
OrthoDBiEOG092C5UG7.

Enzyme and pathway databases

BioCyciYEAST:G3O-33642-MONOMER.

Miscellaneous databases

PROiP41696.

Family and domain databases

Gene3Di3.30.160.60. 4 hits.
InterProiIPR007087. Znf_C2H2.
IPR015880. Znf_C2H2-like.
IPR013087. Znf_C2H2/integrase_DNA-bd.
[Graphical view]
PfamiPF13912. zf-C2H2_6. 1 hit.
[Graphical view]
SMARTiSM00355. ZnF_C2H2. 4 hits.
[Graphical view]
PROSITEiPS00028. ZINC_FINGER_C2H2_1. 4 hits.
PS50157. ZINC_FINGER_C2H2_2. 4 hits.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiAZF1_YEAST
AccessioniPrimary (citable) accession number: P41696
Secondary accession number(s): D6W2H2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: September 7, 2016
This is version 142 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 556 molecules/cell in log phase SD medium.1 Publication

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
  2. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  3. Yeast chromosome XV
    Yeast (Saccharomyces cerevisiae) chromosome XV: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.