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P41684 (CHIT_NPVAC) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 80. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Protein attributes

Sequence length551 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Random hydrolysis of N-acetyl-beta-D-glucosaminide (1->4)-beta-linkages in chitin and chitodextrins.

Subcellular location

Host endoplasmic reticulum lumen Potential.

Sequence similarities

Belongs to the glycosyl hydrolase 18 family. Chitinase class II subfamily.

Ontologies

Keywords
   Biological processCarbohydrate metabolism
Chitin degradation
Polysaccharide degradation
   Cellular componentHost endoplasmic reticulum
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processchitin catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

polysaccharide catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componenthost cell endoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionchitinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 1717 Potential
Chain18 – 551534Probable endochitinase
PRO_0000011950

Regions

Motif548 – 5514Prevents secretion from ER Potential

Sites

Active site3051Proton donor By similarity

Amino acid modifications

Glycosylation1731N-linked (GlcNAc...); by host Potential
Glycosylation4441N-linked (GlcNAc...); by host Potential

Sequences

Sequence LengthMass (Da)Tools
P41684 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 4DDAAD187873BBA2

FASTA55161,368
        10         20         30         40         50         60 
MLYKLLNVLW LVAVSNAIPG TPVIDWADRN YALVEINYEA TAYENLIKPK EQVDVQVSWN 

        70         80         90        100        110        120 
VWNGDIGDIA YVLFDEQQVW KGDAESKRAT IKVLVSGQFN MRVKLCNEDG CSVSDPVLVK 

       130        140        150        160        170        180 
VADTDGGHLA PLEYTWLENN KPGRREDKIV AAYFVEWGVY GRNFPVDKVP LPNLSHLLYG 

       190        200        210        220        230        240 
FIPICGGDGI NDALKTIPGS FESLQRSCKG REDFKVAIHD PWAAVQKPQK GVSAWNEPYK 

       250        260        270        280        290        300 
GNFGQLMAAK LANPHLKILP SIGGWTLSDP FYFMHDVEKR NVFVDSVKEF LQVWKFFDGV 

       310        320        330        340        350        360 
DIDWEFPGGK GANPSLGDAD GDAKTYILLL EELRAMLDDL EAQTGRVYEL TSAISAGYDK 

       370        380        390        400        410        420 
IAVVNYAEAQ KSLGKIFLMS YDFKGAWSNT DLGYQTTVYA PSWNSEELYT THYAVDALLK 

       430        440        450        460        470        480 
QGVDPNKIIV GVAMYGRGWT GVTNYTNDNY FSGTGNGPGS GTWEDGVVDY RQIQKDLNNY 

       490        500        510        520        530        540 
VYTFDSAAQA SYVFDKSKGD LISFDSVDSV LGKVKYVDRN KLGGLFAWEI DADNGDLLNA 

       550 
INAQFKPKDE L 

« Hide

References

[1]"The complete DNA sequence of Autographa californica nuclear polyhedrosis virus."
Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.
Virology 202:586-605(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
L22858 Genomic DNA. Translation: AAA66756.1.
PIRG72865.
RefSeqNP_054156.1. NC_001623.1.

3D structure databases

ProteinModelPortalP41684.
SMRP41684. Positions 17-545.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH18. Glycoside Hydrolase Family 18.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1403959.

Phylogenomic databases

ProtClustDBCLSP2509983.

Family and domain databases

Gene3D2.60.40.10. 1 hit.
3.20.20.80. 2 hits.
InterProIPR011583. Chitinase_II.
IPR013540. ChitinaseA_N.
IPR001223. Glyco_hydro18cat.
IPR001579. Glyco_hydro_18_chit_AS.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
IPR022409. PKD/Chitinase_dom.
[Graphical view]
PfamPF08329. ChitinaseA_N. 1 hit.
PF00704. Glyco_hydro_18. 1 hit.
[Graphical view]
SMARTSM00636. Glyco_18. 1 hit.
SM00089. PKD. 1 hit.
[Graphical view]
SUPFAMSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.
PROSITEPS01095. CHITINASE_18. 1 hit.
PS00014. ER_TARGET. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCHIT_NPVAC
AccessionPrimary (citable) accession number: P41684
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: October 16, 2013
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries