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P41594

- GRM5_HUMAN

UniProt

P41594 - GRM5_HUMAN

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Protein
Metabotropic glutamate receptor 5
Gene
GRM5, GPRC1E, MGLUR5
Organism
Homo sapiens (Human)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at protein leveli

Functioni

G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity.1 Publication

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei64 – 641Glutamate
Binding sitei152 – 1521Glutamate
Binding sitei223 – 2231Glutamate
Binding sitei305 – 3051Glutamate
Binding sitei396 – 3961Glutamate

GO - Molecular functioni

  1. G-protein coupled receptor activity Source: UniProtKB
  2. glutamate receptor activity Source: UniProtKB

GO - Biological processi

  1. G-protein coupled glutamate receptor signaling pathway Source: UniProtKB
  2. activation of MAPKKK activity Source: Ensembl
  3. cognition Source: UniProt
  4. desensitization of G-protein coupled receptor protein signaling pathway Source: Ensembl
  5. learning Source: Ensembl
  6. locomotory behavior Source: Ensembl
  7. negative regulation of locomotion Source: Ensembl
  8. phospholipase C-activating G-protein coupled glutamate receptor signaling pathway Source: ProtInc
  9. positive regulation of long-term neuronal synaptic plasticity Source: Ensembl
  10. protein kinase C-activating G-protein coupled receptor signaling pathway Source: RefGenome
  11. protein phosphorylation Source: Ensembl
  12. regulation of synaptic transmission, glutamatergic Source: RefGenome
  13. regulation of transcription, DNA-templated Source: Ensembl
  14. synaptic transmission Source: ProtInc
Complete GO annotation...

Keywords - Molecular functioni

G-protein coupled receptor, Receptor, Transducer

Enzyme and pathway databases

ReactomeiREACT_18283. G alpha (q) signalling events.
REACT_18319. Class C/3 (Metabotropic glutamate/pheromone receptors).
SignaLinkiP41594.

Names & Taxonomyi

Protein namesi
Recommended name:
Metabotropic glutamate receptor 5
Short name:
mGluR5
Gene namesi
Name:GRM5
Synonyms:GPRC1E, MGLUR5
OrganismiHomo sapiens (Human)
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
ProteomesiUP000005640: Chromosome 11

Organism-specific databases

HGNCiHGNC:4597. GRM5.

Subcellular locationi

Cell membrane; Multi-pass membrane protein 1 Publication

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Topological domaini22 – 579558Extracellular Reviewed prediction
Add
BLAST
Transmembranei580 – 60223Helical; Name=1; Reviewed prediction
Add
BLAST
Topological domaini603 – 61614Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei617 – 63721Helical; Name=2; Reviewed prediction
Add
BLAST
Topological domaini638 – 64811Extracellular Reviewed prediction
Add
BLAST
Transmembranei649 – 66719Helical; Name=3; Reviewed prediction
Add
BLAST
Topological domaini668 – 69326Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei694 – 71421Helical; Name=4; Reviewed prediction
Add
BLAST
Topological domaini715 – 73723Extracellular Reviewed prediction
Add
BLAST
Transmembranei738 – 75922Helical; Name=5; Reviewed prediction
Add
BLAST
Topological domaini760 – 77213Cytoplasmic Reviewed prediction
Add
BLAST
Transmembranei773 – 79523Helical; Name=6; Reviewed prediction
Add
BLAST
Topological domaini796 – 8016Extracellular Reviewed prediction
Transmembranei802 – 82726Helical; Name=7; Reviewed prediction
Add
BLAST
Topological domaini828 – 1212385Cytoplasmic Reviewed prediction
Add
BLAST

GO - Cellular componenti

  1. astrocyte projection Source: Ensembl
  2. cytoplasm Source: Ensembl
  3. dendritic shaft Source: Ensembl
  4. dendritic spine Source: Ensembl
  5. extracellular vesicular exosome Source: UniProt
  6. integral component of plasma membrane Source: UniProtKB
  7. plasma membrane Source: Reactome
  8. postsynaptic density Source: RefGenome
Complete GO annotation...

Keywords - Cellular componenti

Cell membrane, Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28994.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020 Reviewed prediction
Add
BLAST
Chaini21 – 12121192Metabotropic glutamate receptor 5
PRO_0000012932Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi57 ↔ 991 Publication
Glycosylationi88 – 881N-linked (GlcNAc...) Reviewed prediction
Glycosylationi210 – 2101N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi241 ↔ 530 By similarity
Disulfide bondi276 ↔ 2781 Publication
Disulfide bondi365 ↔ 3811 Publication
Glycosylationi378 – 3781N-linked (GlcNAc...) Reviewed prediction
Glycosylationi382 – 3821N-linked (GlcNAc...) Reviewed prediction
Disulfide bondi419 ↔ 4261 Publication
Glycosylationi445 – 4451N-linked (GlcNAc...)1 Publication
Disulfide bondi511 ↔ 531 By similarity
Disulfide bondi515 ↔ 534 By similarity
Disulfide bondi537 ↔ 549 By similarity
Disulfide bondi552 ↔ 565 By similarity
Glycosylationi734 – 7341N-linked (GlcNAc...) Reviewed prediction

Keywords - PTMi

Disulfide bond, Glycoprotein

Proteomic databases

PaxDbiP41594.
PRIDEiP41594.

PTM databases

PhosphoSiteiP41594.

Expressioni

Gene expression databases

ArrayExpressiP41594.
BgeeiP41594.
CleanExiHS_GRM5.
GenevestigatoriP41594.

Organism-specific databases

HPAiHPA014096.

Interactioni

Subunit structurei

The PPXXF motif binds HOMER1, HOMER2 and HOMER3. Interacts with SIAH1, RYR1, RYR2, ITPR1, SHANK1, SHANK3 and GRASP. Interacts with NCDN By similarity.

Protein-protein interaction databases

BioGridi109172. 4 interactions.
STRINGi9606.ENSP00000306138.

Structurei

Secondary structure

Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi29 – 313
Beta strandi34 – 418
Beta strandi49 – 513
Turni52 – 554
Turni62 – 654
Helixi66 – 8116
Beta strandi91 – 977
Helixi102 – 11211
Beta strandi143 – 1475
Helixi152 – 16211
Helixi163 – 1653
Beta strandi169 – 1735
Helixi177 – 1804
Turni182 – 1843
Beta strandi188 – 1925
Helixi195 – 20814
Beta strandi213 – 2197
Helixi222 – 23514
Turni236 – 2394
Beta strandi241 – 2488
Helixi254 – 26714
Turni268 – 2703
Beta strandi273 – 2775
Helixi280 – 29314
Beta strandi300 – 3034
Turni307 – 3093
Helixi311 – 3144
Helixi318 – 3214
Beta strandi325 – 3295
Helixi335 – 3428
Turni346 – 3483
Helixi355 – 3639
Turni387 – 3904
Helixi397 – 41822
Helixi427 – 4293
Helixi434 – 4418
Beta strandi445 – 4473
Beta strandi449 – 4513
Beta strandi453 – 4553
Beta strandi466 – 47510
Beta strandi479 – 48810
Beta strandi491 – 4944

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3LMKX-ray2.44A/B18-505[»]
ProteinModelPortaliP41594.
SMRiP41594. Positions 26-833.

Miscellaneous databases

EvolutionaryTraceiP41594.

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni173 – 1753Glutamate binding

Sequence similaritiesi

Keywords - Domaini

Signal, Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiNOG295200.
HOGENOMiHOG000218636.
HOVERGENiHBG107965.
InParanoidiP41594.
KOiK04604.
OMAiAPLCSSY.
OrthoDBiEOG7Z0JXG.
PhylomeDBiP41594.
TreeFamiTF313240.

Family and domain databases

InterProiIPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR000202. GPCR_3_mtglu_rcpt_5.
IPR019588. Metabotropic_Glu_rcpt_Homer-bd.
IPR028082. Peripla_BP_I.
[Graphical view]
PfamiPF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF10606. GluR_Homer-bdg. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view]
PRINTSiPR00248. GPCRMGR.
PR01055. MTABOTROPC5R.
PR00593. MTABOTROPICR.
SUPFAMiSSF53822. SSF53822. 1 hit.
PROSITEiPS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 2 (identifier: P41594-1) [UniParc]FASTAAdd to Basket

Also known as: 5b

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MVLLLILSVL LLKEDVRGSA QSSERRVVAH MPGDIIIGAL FSVHHQPTVD     50
KVHERKCGAV REQYGIQRVE AMLHTLERIN SDPTLLPNIT LGCEIRDSCW 100
HSAVALEQSI EFIRDSLISS EEEEGLVRCV DGSSSSFRSK KPIVGVIGPG 150
SSSVAIQVQN LLQLFNIPQI AYSATSMDLS DKTLFKYFMR VVPSDAQQAR 200
AMVDIVKRYN WTYVSAVHTE GNYGESGMEA FKDMSAKEGI CIAHSYKIYS 250
NAGEQSFDKL LKKLTSHLPK ARVVACFCEG MTVRGLLMAM RRLGLAGEFL 300
LLGSDGWADR YDVTDGYQRE AVGGITIKLQ SPDVKWFDDY YLKLRPETNH 350
RNPWFQEFWQ HRFQCRLEGF PQENSKYNKT CNSSLTLKTH HVQDSKMGFV 400
INAIYSMAYG LHNMQMSLCP GYAGLCDAMK PIDGRKLLES LMKTNFTGVS 450
GDTILFDENG DSPGRYEIMN FKEMGKDYFD YINVGSWDNG ELKMDDDEVW 500
SKKSNIIRSV CSEPCEKGQI KVIRKGEVSC CWTCTPCKEN EYVFDEYTCK 550
ACQLGSWPTD DLTGCDLIPV QYLRWGDPEP IAAVVFACLG LLATLFVTVV 600
FIIYRDTPVV KSSSRELCYI ILAGICLGYL CTFCLIAKPK QIYCYLQRIG 650
IGLSPAMSYS ALVTKTNRIA RILAGSKKKI CTKKPRFMSA CAQLVIAFIL 700
ICIQLGIIVA LFIMEPPDIM HDYPSIREVY LICNTTNLGV VTPLGYNGLL 750
ILSCTFYAFK TRNVPANFNE AKYIAFTMYT TCIIWLAFVP IYFGSNYKII 800
TMCFSVSLSA TVALGCMFVP KVYIILAKPE RNVRSAFTTS TVVRMHVGDG 850
KSSSAASRSS SLVNLWKRRG SSGETLRYKD RRLAQHKSEI ECFTPKGSMG 900
NGGRATMSSS NGKSVTWAQN EKSSRGQHLW QRLSIHINKK ENPNQTAVIK 950
PFPKSTESRG LGAGAGAGGS AGGVGATGGA GCAGAGPGGP ESPDAGPKAL 1000
YDVAEAEEHF PAPARPRSPS PISTLSHRAG SASRTDDDVP SLHSEPVARS 1050
SSSQGSLMEQ ISSVVTRFTA NISELNSMML STAAPSPGVG APLCSSYLIP 1100
KEIQLPTTMT TFAEIQPLPA IEVTGGAQPA AGAQAAGDAA RESPAAGPEA 1150
AAAKPDLEEL VALTPPSPFR DSVDSGSTTP NSPVSESALC IPSSPKYDTL 1200
IIRDYTQSSS SL 1212
Length:1,212
Mass (Da):132,469
Last modified:October 1, 1996 - v2
Checksum:iA3C73606681C6A25
GO
Isoform 1 (identifier: P41594-2) [UniParc]FASTAAdd to Basket

Also known as: 5a

The sequence of this isoform differs from the canonical sequence as follows:
     877-908: Missing.

Show »
Length:1,180
Mass (Da):128,874
Checksum:i3DBACB2E8B341647
GO
Isoform 3 (identifier: P41594-3) [UniParc]FASTAAdd to Basket

Also known as: 5d

The sequence of this isoform differs from the canonical sequence as follows:
     896-1165: Missing.

Show »
Length:942
Mass (Da):105,432
Checksum:iEF45A35CADD56535
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei877 – 90832Missing in isoform 1.
VSP_002030Add
BLAST
Alternative sequencei896 – 1165270Missing in isoform 3.
VSP_047710Add
BLAST

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D28538 mRNA. Translation: BAA05891.1.
D28539 mRNA. Translation: BAA05892.1.
AY608336 mRNA. Translation: AAT37960.1.
AP000626 Genomic DNA. No translation available.
AP001482 Genomic DNA. No translation available.
AP001828 Genomic DNA. No translation available.
AP003120 Genomic DNA. No translation available.
AP006214 Genomic DNA. No translation available.
AP006215 Genomic DNA. No translation available.
S64316 mRNA. Translation: AAD13954.1.
CCDSiCCDS44694.1. [P41594-1]
CCDS8283.1. [P41594-2]
PIRiJC2131.
JC2132.
RefSeqiNP_000833.1. NM_000842.4. [P41594-2]
NP_001137303.1. NM_001143831.2. [P41594-1]
XP_006718891.1. XM_006718828.1. [P41594-1]
XP_006718892.1. XM_006718829.1. [P41594-1]
XP_006718893.1. XM_006718830.1. [P41594-2]
UniGeneiHs.147361.
Hs.616625.

Genome annotation databases

EnsembliENST00000305432; ENSP00000305905; ENSG00000168959. [P41594-2]
ENST00000305447; ENSP00000306138; ENSG00000168959. [P41594-1]
ENST00000393297; ENSP00000376975; ENSG00000168959. [P41594-3]
ENST00000418177; ENSP00000402912; ENSG00000168959. [P41594-1]
ENST00000455756; ENSP00000405690; ENSG00000168959. [P41594-2]
GeneIDi2915.
KEGGihsa:2915.
UCSCiuc001pcq.3. human. [P41594-1]
uc009yvm.3. human. [P41594-2]

Polymorphism databases

DMDMi1709020.

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
D28538 mRNA. Translation: BAA05891.1 .
D28539 mRNA. Translation: BAA05892.1 .
AY608336 mRNA. Translation: AAT37960.1 .
AP000626 Genomic DNA. No translation available.
AP001482 Genomic DNA. No translation available.
AP001828 Genomic DNA. No translation available.
AP003120 Genomic DNA. No translation available.
AP006214 Genomic DNA. No translation available.
AP006215 Genomic DNA. No translation available.
S64316 mRNA. Translation: AAD13954.1 .
CCDSi CCDS44694.1. [P41594-1 ]
CCDS8283.1. [P41594-2 ]
PIRi JC2131.
JC2132.
RefSeqi NP_000833.1. NM_000842.4. [P41594-2 ]
NP_001137303.1. NM_001143831.2. [P41594-1 ]
XP_006718891.1. XM_006718828.1. [P41594-1 ]
XP_006718892.1. XM_006718829.1. [P41594-1 ]
XP_006718893.1. XM_006718830.1. [P41594-2 ]
UniGenei Hs.147361.
Hs.616625.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3LMK X-ray 2.44 A/B 18-505 [» ]
ProteinModelPortali P41594.
SMRi P41594. Positions 26-833.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 109172. 4 interactions.
STRINGi 9606.ENSP00000306138.

Chemistry

BindingDBi P41594.
ChEMBLi CHEMBL3227.
DrugBanki DB00659. Acamprosate.
GuidetoPHARMACOLOGYi 293.

Protein family/group databases

GPCRDBi Search...

PTM databases

PhosphoSitei P41594.

Polymorphism databases

DMDMi 1709020.

Proteomic databases

PaxDbi P41594.
PRIDEi P41594.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENST00000305432 ; ENSP00000305905 ; ENSG00000168959 . [P41594-2 ]
ENST00000305447 ; ENSP00000306138 ; ENSG00000168959 . [P41594-1 ]
ENST00000393297 ; ENSP00000376975 ; ENSG00000168959 . [P41594-3 ]
ENST00000418177 ; ENSP00000402912 ; ENSG00000168959 . [P41594-1 ]
ENST00000455756 ; ENSP00000405690 ; ENSG00000168959 . [P41594-2 ]
GeneIDi 2915.
KEGGi hsa:2915.
UCSCi uc001pcq.3. human. [P41594-1 ]
uc009yvm.3. human. [P41594-2 ]

Organism-specific databases

CTDi 2915.
GeneCardsi GC11M088237.
HGNCi HGNC:4597. GRM5.
HPAi HPA014096.
MIMi 604102. gene.
neXtProti NX_P41594.
PharmGKBi PA28994.
GenAtlasi Search...

Phylogenomic databases

eggNOGi NOG295200.
HOGENOMi HOG000218636.
HOVERGENi HBG107965.
InParanoidi P41594.
KOi K04604.
OMAi APLCSSY.
OrthoDBi EOG7Z0JXG.
PhylomeDBi P41594.
TreeFami TF313240.

Enzyme and pathway databases

Reactomei REACT_18283. G alpha (q) signalling events.
REACT_18319. Class C/3 (Metabotropic glutamate/pheromone receptors).
SignaLinki P41594.

Miscellaneous databases

ChiTaRSi GRM5. human.
EvolutionaryTracei P41594.
GenomeRNAii 2915.
NextBioi 11555.
PROi P41594.
SOURCEi Search...

Gene expression databases

ArrayExpressi P41594.
Bgeei P41594.
CleanExi HS_GRM5.
Genevestigatori P41594.

Family and domain databases

InterProi IPR001828. ANF_lig-bd_rcpt.
IPR000337. GPCR_3.
IPR011500. GPCR_3_9-Cys_dom.
IPR017978. GPCR_3_C.
IPR017979. GPCR_3_CS.
IPR000162. GPCR_3_mtglu_rcpt.
IPR000202. GPCR_3_mtglu_rcpt_5.
IPR019588. Metabotropic_Glu_rcpt_Homer-bd.
IPR028082. Peripla_BP_I.
[Graphical view ]
Pfami PF00003. 7tm_3. 1 hit.
PF01094. ANF_receptor. 1 hit.
PF10606. GluR_Homer-bdg. 1 hit.
PF07562. NCD3G. 1 hit.
[Graphical view ]
PRINTSi PR00248. GPCRMGR.
PR01055. MTABOTROPC5R.
PR00593. MTABOTROPICR.
SUPFAMi SSF53822. SSF53822. 1 hit.
PROSITEi PS00979. G_PROTEIN_RECEP_F3_1. 1 hit.
PS00980. G_PROTEIN_RECEP_F3_2. 1 hit.
PS00981. G_PROTEIN_RECEP_F3_3. 1 hit.
PS50259. G_PROTEIN_RECEP_F3_4. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and the functional expression of two isoforms of human metabotropic glutamate receptor subtype 5."
    Minakami R., Katsuki F., Yamamoto T., Nakamura K., Sugiyama H.
    Biochem. Biophys. Res. Commun. 199:1136-1143(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORMS 1 AND 2), FUNCTION, SUBCELLULAR LOCATION.
    Tissue: Brain.
  2. Katsuki F.
    Submitted (JUL-1996) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION.
  3. "Molecular cloning and characterization of human metabotropic glutamate receptor 5d; a splice variant with reduced desensitization properties."
    Levinthal C., Storjohann L., Hammerland L.G., Hung B.C.P., Krapcho K.J., Logan M.A., Smith D.L., Trovato R., Vanwagenen B.C., Stormannn T.M.
    Abstr. - Soc. Neurosci. 25:976-976(1999)
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 3).
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
  5. "A variant of metabotropic glutamate receptor subtype 5: an evolutionally conserved insertion with no termination codon."
    Minakami R., Katsuki F., Sugiyama H.
    Biochem. Biophys. Res. Commun. 194:622-627(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 860-952 (ISOFORM 2).
    Tissue: Brain.
  6. "Metabotropic glutamate receptor MGluR5 complexed with glutamate."
    Structural genomics consortium (SGC)
    Submitted (JUL-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.44 ANGSTROMS) OF 18-505 IN COMPLEX WITH GLUTAMATE, GLYCOSYLATION AT ASN-445, DISULFIDE BONDS.

Entry informationi

Entry nameiGRM5_HUMAN
AccessioniPrimary (citable) accession number: P41594
Secondary accession number(s): Q6J164
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: October 1, 1996
Last modified: September 3, 2014
This is version 136 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. 7-transmembrane G-linked receptors
    List of 7-transmembrane G-linked receptor entries
  2. Human chromosome 11
    Human chromosome 11: entries, gene names and cross-references to MIM
  3. MIM cross-references
    Online Mendelian Inheritance in Man (MIM) cross-references in UniProtKB/Swiss-Prot
  4. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  5. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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