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Protein

DNA-directed RNA polymerase subunit B''

Gene

rpoB2

Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Cofactori

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Transcription

Keywords - Ligandi

Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit B'' (EC:2.7.7.6)
Gene namesi
Name:rpoB2
Ordered Locus Names:Mevan_0671
OrganismiMethanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Taxonomic identifieri406327 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi
  • UP000001107 Componenti: Chromosome

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740351 – 499DNA-directed RNA polymerase subunit B''Add BLAST499

Interactioni

Protein-protein interaction databases

STRINGi406327.Mevan_0671.

Structurei

3D structure databases

ProteinModelPortaliP41558.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.Curated

Phylogenomic databases

eggNOGiarCOG01762. Archaea.
COG0085. LUCA.
HOGENOMiHOG000222951.
KOiK03045.
OMAiGKICPSE.

Family and domain databases

Gene3Di3.90.1110.10. 1 hit.
InterProiIPR015712. DNA-dir_RNA_pol_su2.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P41558-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESRVIVDAF FRENSLVKHH IDSYDDFVEN KIQGIIDEVT GVETEIKGGY
60 70 80 90 100
KVSFGKVRVT KPINKEADGS VKEITPMEAR IRNLAYSAPL YLEMIPLIGE
110 120 130 140 150
GDEEKTLSPI EVYIGELPVM LGAKICHLSG KSEEDMINYG EDPKDPLGYF
160 170 180 190 200
IVNGSEKAVV AQEDLIPNRI LCEKVEKNNK IVDIAKVFST RHGFRALCTV
210 220 230 240 250
ERSPDGLLNV SFPGMPSTIP LVILMRALGA ESDREIMELI SDEPTVVMQL
260 270 280 290 300
VANLQEAREE HGINTTEDAL EHIGKRVAPG QPKEYKLKRA ETILCNYLLP
310 320 330 340 350
HMGIESEKLG AKCKYLGRMA KNSIELYLGS RVEDDKDHYA NKRLKLAGDL
360 370 380 390 400
MEDLFRHSFN QLIKDIKYQL ERQAIRNKEP SIQAAVRSDV LTERMRHAMA
410 420 430 440 450
TGNWVGGRTG VSQLLDRTSY LATVSQLRRV VSPLSRSQPH FEARDLHATQ
460 470 480 490
WGKICPSETP EGPNCGLVKN LAVMCKVTTD EEDEGIIQLI KEIGLSKDI
Length:499
Mass (Da):55,900
Last modified:November 1, 1995 - v1
Checksum:i96B5672C259DC2C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73293 Genomic DNA. Translation: CAA51726.1.
CP000742 Genomic DNA. Translation: ABR54577.1.
PIRiS47160.
RefSeqiWP_011972479.1. NC_009634.1.

Genome annotation databases

EnsemblBacteriaiABR54577; ABR54577; Mevan_0671.
GeneIDi5325115.
KEGGimvn:Mevan_0671.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73293 Genomic DNA. Translation: CAA51726.1.
CP000742 Genomic DNA. Translation: ABR54577.1.
PIRiS47160.
RefSeqiWP_011972479.1. NC_009634.1.

3D structure databases

ProteinModelPortaliP41558.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi406327.Mevan_0671.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiABR54577; ABR54577; Mevan_0671.
GeneIDi5325115.
KEGGimvn:Mevan_0671.

Phylogenomic databases

eggNOGiarCOG01762. Archaea.
COG0085. LUCA.
HOGENOMiHOG000222951.
KOiK03045.
OMAiGKICPSE.

Family and domain databases

Gene3Di3.90.1110.10. 1 hit.
InterProiIPR015712. DNA-dir_RNA_pol_su2.
IPR007644. RNA_pol_bsu_protrusion.
IPR007642. RNA_pol_Rpb2_2.
IPR007645. RNA_pol_Rpb2_3.
[Graphical view]
PANTHERiPTHR20856. PTHR20856. 1 hit.
PfamiPF04563. RNA_pol_Rpb2_1. 1 hit.
PF04561. RNA_pol_Rpb2_2. 1 hit.
PF04565. RNA_pol_Rpb2_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRPOB2_METVS
AccessioniPrimary (citable) accession number: P41558
Secondary accession number(s): A6UQ05
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: November 2, 2016
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.