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Protein

DNA-directed RNA polymerase subunit B''

Gene

rpoB2

Organism
Methanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. The B (B''+B' and beta) subunits have been implicated in DNA promoter recognition and also in nucleotide binding.

Catalytic activityi

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).

Cofactori

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionNucleotidyltransferase, Transferase
Biological processTranscription
LigandZinc

Enzyme and pathway databases

BioCyciMVAN406327:G1G99-692-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
DNA-directed RNA polymerase subunit B'' (EC:2.7.7.6)
Gene namesi
Name:rpoB2
Ordered Locus Names:Mevan_0671
OrganismiMethanococcus vannielii (strain ATCC 35089 / DSM 1224 / JCM 13029 / OCM 148 / SB)
Taxonomic identifieri406327 [NCBI]
Taxonomic lineageiArchaeaEuryarchaeotaMethanococciMethanococcalesMethanococcaceaeMethanococcus
Proteomesi

Subcellular locationi

Keywords - Cellular componenti

DNA-directed RNA polymerase

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000740351 – 499DNA-directed RNA polymerase subunit B''Add BLAST499

Interactioni

Protein-protein interaction databases

STRINGi406327.Mevan_0671

Structurei

3D structure databases

ProteinModelPortaliP41558
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RNA polymerase beta chain family.Curated

Phylogenomic databases

eggNOGiarCOG01762 Archaea
COG0085 LUCA
HOGENOMiHOG000222951
KOiK03045
OMAiASMGVEG
OrthoDBiPOG093Z01G2

Family and domain databases

InterProiView protein in InterPro
IPR015712 DNA-dir_RNA_pol_su2
IPR007644 RNA_pol_bsu_protrusion
IPR007642 RNA_pol_Rpb2_2
IPR007645 RNA_pol_Rpb2_3
PANTHERiPTHR20856 PTHR20856, 1 hit
PfamiView protein in Pfam
PF04563 RNA_pol_Rpb2_1, 1 hit
PF04561 RNA_pol_Rpb2_2, 1 hit
PF04565 RNA_pol_Rpb2_3, 1 hit

Sequencei

Sequence statusi: Complete.

P41558-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESRVIVDAF FRENSLVKHH IDSYDDFVEN KIQGIIDEVT GVETEIKGGY
60 70 80 90 100
KVSFGKVRVT KPINKEADGS VKEITPMEAR IRNLAYSAPL YLEMIPLIGE
110 120 130 140 150
GDEEKTLSPI EVYIGELPVM LGAKICHLSG KSEEDMINYG EDPKDPLGYF
160 170 180 190 200
IVNGSEKAVV AQEDLIPNRI LCEKVEKNNK IVDIAKVFST RHGFRALCTV
210 220 230 240 250
ERSPDGLLNV SFPGMPSTIP LVILMRALGA ESDREIMELI SDEPTVVMQL
260 270 280 290 300
VANLQEAREE HGINTTEDAL EHIGKRVAPG QPKEYKLKRA ETILCNYLLP
310 320 330 340 350
HMGIESEKLG AKCKYLGRMA KNSIELYLGS RVEDDKDHYA NKRLKLAGDL
360 370 380 390 400
MEDLFRHSFN QLIKDIKYQL ERQAIRNKEP SIQAAVRSDV LTERMRHAMA
410 420 430 440 450
TGNWVGGRTG VSQLLDRTSY LATVSQLRRV VSPLSRSQPH FEARDLHATQ
460 470 480 490
WGKICPSETP EGPNCGLVKN LAVMCKVTTD EEDEGIIQLI KEIGLSKDI
Length:499
Mass (Da):55,900
Last modified:November 1, 1995 - v1
Checksum:i96B5672C259DC2C2
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X73293 Genomic DNA Translation: CAA51726.1
CP000742 Genomic DNA Translation: ABR54577.1
PIRiS47160
RefSeqiWP_011972479.1, NC_009634.1

Genome annotation databases

EnsemblBacteriaiABR54577; ABR54577; Mevan_0671
GeneIDi5325115
KEGGimvn:Mevan_0671

Entry informationi

Entry nameiRPOB2_METVS
AccessioniPrimary (citable) accession number: P41558
Secondary accession number(s): A6UQ05
Entry historyiIntegrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: March 28, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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