Skip Header

Contribute Send feedback
Read comments (?) or add your own

P41476 (PNKL_NPVAC) Reviewed, UniProtKB/Swiss-Prot

Last modified December 14, 2011. Version 48. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Putative bifunctional polynucleotide kinase/RNA ligase

Including the following 2 domains:

  1. Polynucleotide kinase
    Short name=PNK
    EC=2.7.1.78
    Alternative name(s):
    Polynucleotide 5'-hydroxy-kinase
  2. RNA ligase
    EC=6.5.1.3
Gene names
Name:PNK/PNL
OrganismAutographa californica nuclear polyhedrosis virus (AcMNPV) [Complete proteome]
Taxonomic identifier46015 [NCBI]
Taxonomic lineageViruses › dsDNA viruses, no RNA stage › Baculoviridae › Alphabaculovirus
Virus hostLepidoptera (butterflies and moths) [TaxID: 7088]

Protein attributes

Sequence length694 AA.
Sequence statusComplete.
Protein existencePredicted

General annotation (Comments)

Catalytic activity

ATP + (ribonucleotide)(n) + (ribonucleotide)(m) = AMP + diphosphate + (ribonucleotide)(n+m).

ATP + 5'-dephospho-DNA = ADP + 5'-phospho-DNA.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 694694Putative bifunctional polynucleotide kinase/RNA ligase
PRO_0000132846

Regions

Nucleotide binding401 – 4088ATP Potential

Sequences

Sequence LengthMass (Da)Tools
P41476 [UniParc].

Last modified November 1, 1995. Version 1.
Checksum: 3B81C296C54FCAEA

FASTA69480,760
        10         20         30         40         50         60 
MLHVSRLLAN GGVKNLCDKF KVKIKNYTEH DLMVLNYESF ERDRDHPVVV ECRGLILNSR 

        70         80         90        100        110        120 
TYAVVSRSFD RFFNFQELLQ NIGGEDAHHK LFQSKENFKF YEKIDGSLIK IYKYNGEWHA 

       130        140        150        160        170        180 
STRGSAFAEN LCVSDVTFKR LVLQALQLDE AHNQFQALCN EYLDCASTHM FELTSKHNRI 

       190        200        210        220        230        240 
VTVYDEQPTL WYLASRNNET GDYFYCSNLP FCKYPKCYEF TSVQECVEHA AQLKNLEEGF 

       250        260        270        280        290        300 
VVYDKNNAPL CKIKSDVYLN MHKNQSRAEN PTKLAQLVIN GEHDDFLALF PHLKSVIKPY 

       310        320        330        340        350        360 
VDARNTFTNE STINIMVSGL TLNQQRFNEL VQTLPWKCLA YRCRKAQTID VESEFLKLTE 

       370        380        390        400        410        420 
PEKIKMIKNI IKFVSTKQAL NNKLAPTIKL PSSKQLLVLI GISGSGKSTY AKSLKGYTEI 

       430        440        450        460        470        480 
NRDDVRVKLF LNGDYTKLNA FYNQSRKCRQ TKEEQITKMC IEQFLKAAKC GANVVVSDTN 

       490        500        510        520        530        540 
LNTQSVDMWQ KMAATHNYHF LTRLMDVSLE TALERNYKRS DKFPLNPETI KKQYKKFLKV 

       550        560        570        580        590        600 
NNFEYYVPVG DKFPRAVLCD LDGTVALPTN RSFYDFDNRV AQDEARLDVI TCVKYLANCH 

       610        620        630        640        650        660 
DAIIVFMSGR SVICEQPTRN WIEKYFDIKS YKLFMRPSDD TCKDYLLKLK LFNNYIRGKY 

       670        680        690 
NVIAVFDDRP CVVRMWQDLK IPTVFNVCRD YLEF

« Hide

References

[1]"The complete DNA sequence of Autographa californica nuclear polyhedrosis virus."
Ayres M.D., Howard S.C., Kuzio J., Lopez-Ferber M., Possee R.D.
Virology 202:586-605(1994) [PubMed: 8030224] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: C6.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		L22858 Genomic DNA. Translation: AAA66716.1.
PIRG72860.
RefSeqNP_054116.1. NC_001623.1.

3D structure databases

ProteinModelPortalP41476.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1403919.

Phylogenomic databases

ProtClustDBCLSP2509948.

Family and domain databases

InterProIPR023214. HAD-like_dom.
IPR019039. RNA_ligase_T4-RnlA-like.
IPR010488. Zeta_toxin_domain.
[Graphical view]
Gene3DG3DSA:3.40.50.1000. HAD-like_dom. 1 hit.
PfamPF09511. RNA_lig_T4_1. 1 hit.
PF06414. Zeta_toxin. 1 hit.
[Graphical view]
SUPFAMSSF56784. HAD-like_dom. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNKL_NPVAC
AccessionPrimary (citable) accession number: P41476
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: December 14, 2011
This is version 48 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info