Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Putative type II secretion system protein G

Gene

gspG

Organism
Escherichia coli (strain K12)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins.Curated

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Protein transport, Transport

Enzyme and pathway databases

BioCyciEcoCyc:G7706-MONOMER.
ECOL316407:JW3290-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Putative type II secretion system protein G
Short name:
T2SS protein G
Alternative name(s):
Protein transport protein HofG
Putative general secretion pathway protein G
Gene namesi
Name:gspG
Synonyms:hofG, hopG
Ordered Locus Names:b3328, JW3290
OrganismiEscherichia coli (strain K12)
Taxonomic identifieri83333 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaEnterobacterialesEnterobacteriaceaeEscherichia
Proteomesi
  • UP000000318 Componenti: Chromosome
  • UP000000625 Componenti: Chromosome

Organism-specific databases

EcoGeneiEG12886. gspG.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Propeptidei1 – 99By similarityPRO_0000024200
Chaini10 – 145136Putative type II secretion system protein GPRO_0000024201Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei10 – 101N-methylphenylalaninePROSITE-ProRule annotation

Keywords - PTMi

Methylation

Proteomic databases

PaxDbiP41442.

Expressioni

Inductioni

Silenced by the DNA-binding protein H-NS under standard growth conditions.1 Publication

Interactioni

Protein-protein interaction databases

BioGridi4262167. 250 interactions.
STRINGi511145.b3328.

Structurei

3D structure databases

ProteinModelPortaliP41442.
SMRiP41442. Positions 35-138.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the GSP G family.Curated

Phylogenomic databases

eggNOGiENOG4108VAU. Bacteria.
COG2165. LUCA.
HOGENOMiHOG000008196.
InParanoidiP41442.
KOiK02456.
OMAiIGNWNVG.
OrthoDBiEOG657JHX.
PhylomeDBiP41442.

Family and domain databases

InterProiIPR000983. Bac_GSPG_pilin.
IPR012902. N_methyl_site.
IPR013545. T2SS_protein-G.
IPR010054. Type2_sec_GspG.
[Graphical view]
PfamiPF13544. N_methyl_2. 1 hit.
PF08334. T2SSG. 1 hit.
[Graphical view]
PRINTSiPR00813. BCTERIALGSPG.
TIGRFAMsiTIGR02532. IV_pilin_GFxxxE. 1 hit.
TIGR01710. typeII_sec_gspG. 1 hit.
PROSITEiPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P41442-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRATDKQRGF TLLEIMVVIV IIGVLASLVV PNLMGNKEKA DKQKAVSDIV
60 70 80 90 100
ALENALDMYK LDNHHYPTTN QGLESLVEAP TLPPLAANYN KEGYIKRLPA
110 120 130 140
DPWGNDYVLV NPGEHGAYDL LSAGPDGEMG TEDDITNWGL SKKKK
Length:145
Mass (Da):15,905
Last modified:November 1, 1995 - v1
Checksum:iCBCD67D743810072
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20786 Genomic DNA. Translation: AAA69031.1.
U18997 Genomic DNA. Translation: AAA58125.1.
U00096 Genomic DNA. Translation: AAC76353.1.
AP009048 Genomic DNA. Translation: BAE77963.1.
PIRiB56150.
RefSeqiNP_417787.1. NC_000913.3.
WP_001202874.1. NZ_LN832404.1.

Genome annotation databases

EnsemblBacteriaiAAC76353; AAC76353; b3328.
BAE77963; BAE77963; BAE77963.
GeneIDi947827.
KEGGiecj:JW3290.
eco:b3328.
PATRICi32122088. VBIEscCol129921_3421.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U20786 Genomic DNA. Translation: AAA69031.1.
U18997 Genomic DNA. Translation: AAA58125.1.
U00096 Genomic DNA. Translation: AAC76353.1.
AP009048 Genomic DNA. Translation: BAE77963.1.
PIRiB56150.
RefSeqiNP_417787.1. NC_000913.3.
WP_001202874.1. NZ_LN832404.1.

3D structure databases

ProteinModelPortaliP41442.
SMRiP41442. Positions 35-138.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi4262167. 250 interactions.
STRINGi511145.b3328.

Proteomic databases

PaxDbiP41442.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAC76353; AAC76353; b3328.
BAE77963; BAE77963; BAE77963.
GeneIDi947827.
KEGGiecj:JW3290.
eco:b3328.
PATRICi32122088. VBIEscCol129921_3421.

Organism-specific databases

EchoBASEiEB2723.
EcoGeneiEG12886. gspG.

Phylogenomic databases

eggNOGiENOG4108VAU. Bacteria.
COG2165. LUCA.
HOGENOMiHOG000008196.
InParanoidiP41442.
KOiK02456.
OMAiIGNWNVG.
OrthoDBiEOG657JHX.
PhylomeDBiP41442.

Enzyme and pathway databases

BioCyciEcoCyc:G7706-MONOMER.
ECOL316407:JW3290-MONOMER.

Miscellaneous databases

PROiP41442.

Family and domain databases

InterProiIPR000983. Bac_GSPG_pilin.
IPR012902. N_methyl_site.
IPR013545. T2SS_protein-G.
IPR010054. Type2_sec_GspG.
[Graphical view]
PfamiPF13544. N_methyl_2. 1 hit.
PF08334. T2SSG. 1 hit.
[Graphical view]
PRINTSiPR00813. BCTERIALGSPG.
TIGRFAMsiTIGR02532. IV_pilin_GFxxxE. 1 hit.
TIGR01710. typeII_sec_gspG. 1 hit.
PROSITEiPS00409. PROKAR_NTER_METHYL. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Identification of the hopG gene, a component of Escherichia coli K-12 type II export system, and its conservation among different pathogenic Escherichia coli and Shigella isolates."
    Stojiljkovic I., Schoenherr R., Kusters J.G.
    J. Bacteriol. 177:1892-1895(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: K12.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / MG1655 / ATCC 47076.
  3. "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110."
    Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.
    Mol. Syst. Biol. 2:E1-E5(2006) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: K12 / W3110 / ATCC 27325 / DSM 5911.
  4. "The cryptic general secretory pathway (gsp) operon of Escherichia coli K-12 encodes functional proteins."
    Francetic O., Pugsley A.P.
    J. Bacteriol. 178:3544-3549(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: LACK OF EXPRESSION, GENE NAME.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.
  5. "Expression of the endogenous type II secretion pathway in Escherichia coli leads to chitinase secretion."
    Francetic O., Belin D., Badaut C., Pugsley A.P.
    EMBO J. 19:6697-6703(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: LACK OF EXPRESSION, TRANSCRIPTIONAL REGULATION.
    Strain: K12 / MC4100 / ATCC 35695 / DSM 6574.

Entry informationi

Entry nameiGSPG_ECOLI
AccessioniPrimary (citable) accession number: P41442
Secondary accession number(s): Q2M6Z3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1995
Last sequence update: November 1, 1995
Last modified: January 20, 2016
This is version 112 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Miscellaneous

Part of a cryptic operon that encodes proteins involved in type II secretion machinery in other organisms, but is not expressed in strain K12.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Escherichia coli
    Escherichia coli (strain K12): entries and cross-references to EcoGene
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.