P41393 (GLND_KLEOX) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
[Protein-PII] uridylyltransferase
Short name=PII uridylyl-transferase
EC=2.7.7.59

Alternative name(s):
UTase
Uridylyl-removing enzyme

Gene names

Name:

glnD

Organism

Klebsiella oxytoca

Taxonomic identifier

571 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Klebsiella

Protein attributes

Sequence length	887 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein. HAMAP-Rule MF_00277
Catalytic activity	UTP + [protein-PII] = diphosphate + uridylyl-[protein-PII]. HAMAP-Rule MF_00277
Sequence similarities	Belongs to the GlnD family.

Ontologies

Keywords
Biological process	Nitrogen fixation
Molecular function	Nucleotidyltransferase Transferase
Gene Ontology (GO)
Biological_process	nitrogen fixation Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	[protein-PII] uridylyltransferase activity Inferred from electronic annotation. Source: HAMAP amino acid binding Inferred from electronic annotation. Source: InterPro metal ion binding Inferred from electronic annotation. Source: InterPro phosphoric diester hydrolase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 887	887	[Protein-PII] uridylyltransferase HAMAP-Rule MF_00277		PRO_0000192739

Sequences

	Sequence		Length	Mass (Da)
	P41393 [UniParc]. Last modified November 1, 1995. Version 1. Checksum: 73782E94DA434CAC	FASTA	887	102,344
	10 20 30 40 50 60 MSNSLSNTVP PDLSAQPENP GEWPKSDFNC ATIKALIDAF QRWLGEAFDS GIAAERLIEA 70 80 90 100 110 120 RTEFIDQLLQ RLWVEYGFGS INDIALVAVG GYGRGELHPL SDIDLLILSR KKLPDEQAQK 130 140 150 160 170 180 VGERLALLWD IKLEVGHSVR TLEECLLEGL SDLSVATNLI ESRLLIGDVA LFLELQKHIF 190 200 210 220 230 240 SDGFWPSEKF FAAKVEEQND RHQRYHGTSY NLEPDVKSSP GGLRDIHTLQ WIARRHFGAT 250 260 270 280 290 300 SLDEMVGFGF LTEAERNELN ECLHQLWRIR FALHLELNRY DNRLLFDRQF SVARRLRYEG 310 320 330 340 350 360 ESNQPIEHMM KDFFRVTRRV SELNQMLIQL FEEAILALTE DEKPRPIDDD FQLRGTLIDL 370 380 390 400 410 420 RDDTLFIREP QAILRMFYTM VRNSSITGIY STTVRHLRHA RRHLTQPLCY IPEARTLFLS 430 440 450 460 470 480 MLRHQGGLSR GLLPMHRHSV LWAYMPQWSH IVGQMQFDLF HAYTVDEHTI RVLLKLESFA 490 500 510 520 530 540 KEETRSRHPL WLELWPRLTH PELILIAALF HDIAKGAGGD HSILGAQDVL KFAELHGLNC 550 560 570 580 590 600 AQTQLVAWLV RHQLLMSVTA QRRDIQDPEV IKQFAEEVQT ENRLHYLVCL TVADICATNE 610 620 630 640 650 660 NLWNSWKQSL LRELYFATEK QLRRGMQNTP DMRERVRHHQ LQALALLRME NINEQALHQI 670 680 690 700 710 720 WNRCRANYFV RHTPNQLAWH ARNLLKHDLS KPMILLSSHA TRGGTEIFIW SPDRPYLFAA 730 740 750 760 770 780 VSAELDRRNL SVHDAQIFTT RDGMAMDTFI VLEPDGSPLS ADRTQMIRVG LEQTLSQRSW 790 800 810 820 830 840 QPPAPRRQAA KLRHFSVPTE VNFLPTHTDR KSFLELIALD QPGLLARVGQ VFADLGISLH 850 860 870 880 GARITTIGER VEDLFIIATA DRRALNNELQ QEVQQRLTEA LNPNDKG

References

[1]	"The role of uridylyltransferase in the control of Klebsiella pneumoniae nif gene regulation." Edwards R.A., Merrick M.J. Mol. Gen. Genet. 247:189-198(1995) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: M5a1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	X78685 Genomic DNA. Translation: CAA55353.1.
PIR	S43196. S54756.
3D structure databases
ProteinModelPortal	P41393.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Family and domain databases
Gene3D	1.10.3210.10. 1 hit.
HAMAP	MF_00277. PII_uridylyl-transf.
InterPro	IPR002912. ACT_dom. IPR010043. GlnD_Uridyltrans. IPR003607. HD/PDEase_dom. IPR006674. HD_domain. IPR002934. Nucleotidyltransferase. IPR013546. PII_UdlTrfase/GS_AdlTrfase. [Graphical view]
PANTHER	PTHR13734:SF1. PTHR13734:SF1. 1 hit.
Pfam	PF01842. ACT. 2 hits. PF08335. GlnD_UR_UTase. 1 hit. PF01966. HD. 1 hit. PF01909. NTP_transf_2. 1 hit. [Graphical view]
PIRSF	PIRSF006288. PII_uridyltransf. 1 hit.
SMART	SM00471. HDc. 1 hit. [Graphical view]
TIGRFAMs	TIGR01693. UTase_glnD. 1 hit.
ProtoNet	Search...

Entry information

Entry name

GLND_KLEOX

Accession

Primary (citable) accession number: P41393

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1995
Last sequence update:	November 1, 1995
Last modified:	April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program