P41344 (FENR1_ORYSJ) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase, leaf isozyme, chloroplastic
Short name=FNR
EC=1.18.1.2

Gene names

Ordered Locus Names:	Os06g0107700, LOC_Os06g01850
ORF Names:	P0514G12.8, P0644B06.52

Organism

Oryza sativa subsp. japonica (Rice)

Taxonomic identifier

39947 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › Liliopsida › Poales › Poaceae › BEP clade › Ehrhartoideae › Oryzeae › Oryza

Protein attributes

Sequence length	362 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Evidence at transcript level

General annotation (Comments)

Function	May play a key role in regulating the relative amounts of cyclic and non-cyclic electron flow to meet the demands of the plant for ATP and reducing power.
Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH.
Cofactor	FAD.
Pathway	Energy metabolism; photosynthesis.
Subcellular location	Plastid › chloroplast stroma. Plastid › chloroplast thylakoid membrane; Peripheral membrane protein; Stromal side Probable. Note: In the vicinity of the photosystem I in the non-stacked and fringe portion of the membrane.
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 1 family. Contains 1 FAD-binding FR-type domain.

Ontologies

Keywords
Biological process	Electron transport Photosynthesis Transport
Cellular component	Chloroplast Membrane Plastid Thylakoid
Domain	Transit peptide
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	chloroplast stroma Inferred from electronic annotation. Source: UniProtKB-SubCell chloroplast thylakoid membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	NADP binding Inferred from electronic annotation. Source: InterPro ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC flavin adenine dinucleotide binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 62	62	Chloroplast Potential
	Chain	63 – 362	300	Ferredoxin--NADP reductase, leaf isozyme, chloroplastic		PRO_0000019409
Regions
	Domain	83 – 205	123	FAD-binding FR-type
	Nucleotide binding	141 – 144	4	FAD By similarity
	Nucleotide binding	162 – 164	3	FAD By similarity
	Nucleotide binding	179 – 181	3	FAD By similarity
	Nucleotide binding	252 – 253	2	NADP By similarity
	Nucleotide binding	282 – 283	2	NADP By similarity
	Nucleotide binding	321 – 322	2	NADP By similarity
Sites
	Binding site	144	1	NADP By similarity
	Binding site	164	1	NADP By similarity
	Binding site	168	1	FAD By similarity
	Binding site	220	1	FAD By similarity
	Binding site	220	1	NADP; via amide nitrogen By similarity
	Binding site	292	1	NADP By similarity
	Binding site	360	1	NADP By similarity

Sequences

	Sequence		Length	Mass (Da)
	P41344 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: 1B6034A8A76E4F29	FASTA	362	40,008
	10 20 30 40 50 60 MAAVTAAAVS TSAAAAVTKA SPSPAHCFLP CPPRTRAAHQ RGLLLRAQVS TTDAAAVAAA 70 80 90 100 110 120 PAKKEKISKK HDEGVVTNKY RPKEPYVGKC LLNTKITADD APGETWHMVF STEGEIPYRE 130 140 150 160 170 180 GQSIGVIADG VDKNGKPHKL RLYSIASSAL GDFGDSKTVS LCVKRLVYTN DQGEIVKGVC 190 200 210 220 230 240 SNFLCDLKPG SDVKITGPVG KEMLMPKDPN ANIIMLATGT GIAPFRSFLW KMFFEKYDDY 250 260 270 280 290 300 KFNGLAWLFL GVPTSSSLLY KEEFDKMKAK APENFRVDYA VSREQTNAQG EKMYIQTRMA 310 320 330 340 350 360 EYKEELWELL KKDHTYVYMC GLKGMEKGID DIMVSLAAKD GIDWADYKKQ LKKGEQWNVE VY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence of a cDNA encoding rice (Oryza sativa L.) leaf ferredoxin-NADP+ reductase." Aoki H., Doyama N., Ida S. Plant Physiol. 104:1473-1474(1994) [PubMed: 8016278] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [MRNA]. Strain: cv. Kinmaze. Tissue: Leaf.
[2]	"The map-based sequence of the rice genome." International rice genome sequencing project (IRGSP) Nature 436:793-800(2005) [PubMed: 16100779] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: cv. Nipponbare.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	D17790 mRNA. Translation: BAA04616.1. AP000616 Genomic DNA. Translation: BAA85425.1. AP001129 Genomic DNA. Translation: BAA90642.1.
PIR	T04349.
RefSeq	NP_001056570.1. NM_001063105.1.
UniGene	Os.10696.
3D structure databases
ProteinModelPortal	P41344.
SMR	P41344. Positions 58-362.
ModBase	Search...
Protein-protein interaction databases
STRING	P41344.
Proteomic databases
PRIDE	P41344.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	LOC_Os06g01850.1; LOC_Os06g01850.1; LOC_Os06g01850.
GeneID	4339874.
KEGG	osa:4339874.
Organism-specific databases
Gramene	P41344.
Phylogenomic databases
OMA	GRMYIQD.
PhylomeDB	P41344.
ProtClustDB	PLN03115.
Family and domain databases
InterPro	IPR017927. Fd_Rdtase_FAD-bd. IPR015701. Fd_Red. IPR001709. Flavoprot_Pyr_Nucl_cyt_Rdtase. IPR012146. FNR. IPR008333. OxRdtase_FAD-bd_dom. IPR001433. OxRdtase_FAD/NAD-bd. IPR017938. Riboflavin_synthase-like_b-brl. [Graphical view]
KO	K02641.
PANTHER	PTHR19384:SF1. FRD_Red. 1 hit.
Pfam	PF00970. FAD_binding_6. 1 hit. PF00175. NAD_binding_1. 1 hit. [Graphical view]
PIRSF	PIRSF000361. Frd-NADP+_RD. 1 hit.
PRINTS	PR00371. FPNCR.
SUPFAM	SSF63380. Riboflavin_synthase_like_b-brl. 1 hit.
PROSITE	PS51384. FAD_FR. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

FENR1_ORYSJ

Accession

Primary (citable) accession number: P41344
Secondary accession number(s): Q7F8E8

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	January 25, 2012
This is version 87 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program