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P41268 (NCAP_PUUME) Reviewed, UniProtKB/Swiss-Prot

Last modified October 16, 2013. Version 43. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nucleoprotein
Alternative name(s):
Nucleocapsid protein
Short name=Protein N
Gene names
Name:N
OrganismPuumala virus (strain Evo/12CG/93)
Taxonomic identifier38999 [NCBI]
Taxonomic lineageVirusesssRNA negative-strand virusesBunyaviridaeHantavirus
Virus hostHomo sapiens (Human) [TaxID: 9606]
Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]

Protein attributes

Sequence length433 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication By similarity.

Subcellular location

Virion. Note: Internal protein of virus particle.

Sequence similarities

Belongs to the hantavirus nucleocapsid protein family.

Ontologies

Keywords
   Cellular componentCapsid protein
Helical capsid protein
Virion
   LigandRNA-binding
Viral nucleoprotein
   Molecular functionRibonucleoprotein
Gene Ontology (GO)
   Cellular_componenthelical viral capsid

Inferred from electronic annotation. Source: UniProtKB-KW

ribonucleoprotein complex

Inferred from electronic annotation. Source: UniProtKB-KW

viral nucleocapsid

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular_functionRNA binding

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 433433Nucleoprotein
PRO_0000222012

Sequences

Sequence LengthMass (Da)Tools
P41268 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: EF2B4DF273132F93

FASTA43349,508
        10         20         30         40         50         60 
MSDLTDIQED ITRHEQQLVV ARQKLKDAER AVEVDPDDVN KNTLQARQQT VSALEDKLAD 

        70         80         90        100        110        120 
YKRRMADAVS RKKMDTKPTD PTGIEPDDHL KERSSLRYGN VLDVNAIDIE EPSGQTADWY 

       130        140        150        160        170        180 
TIGVYVIGFT IPIILKALYM LSTRGRQTVK ENKGTRIRFK DDTSFEDING IRRPKHLYVS 

       190        200        210        220        230        240 
MPTAQSTMKA EELTPGRFRT IVCGLFPTQI QVRNIMSPVM GVIGFSFFVK DWPERIREFM 

       250        260        270        280        290        300 
EKECPFIKPE IKPGTPAQEM EMLKRNKIYF MQRQDVLDKN HVADIDKLID YAASGDPTSP 

       310        320        330        340        350        360 
DNIDSPNAPW VFACAPDRCP PTCIYVAGMA ELGAFFSILQ DMRNTIMASK TVGTAEEKLR 

       370        380        390        400        410        420 
KKSSFYQSYL RRTQSMGIQL DQRIILLFML EWGKEMVDHF HLGDDMDPEL RGLAQALIDQ 

       430 
KVKEISNQEP LKI 

« Hide

References

[1]"Genetic variation of wild Puumala viruses within the serotype, local rodent populations and individual animal."
Plyusnin A., Vapalahti O., Lehvaeslaiho H., Apekina N., Mikhailova T., Gavilovskaya I., Laakkonen J., Niemimaa J., Henttonen H., Brummer-Korvenkontio M., Vaheri A.
Virus Res. 38:25-41(1995) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z30703 Genomic RNA. Translation: CAA83188.1.
Z30702 Genomic RNA. Translation: CAA83187.1.
PIRS43008.

3D structure databases

ProteinModelPortalP41268.
SMRP41268. Positions 1-74.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR002214. Hanta_nucleocap.
[Graphical view]
PfamPF00846. Hanta_nucleocap. 1 hit.
[Graphical view]
PIRSFPIRSF003949. N_HantaV. 1 hit.
ProDomPD001501. Hanta_nucleocap. 1 hit.
[Graphical view] [Entries sharing at least one domain]
ProtoNetSearch...

Entry information

Entry nameNCAP_PUUME
AccessionPrimary (citable) accession number: P41268
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 16, 2013
This is version 43 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families