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P41268

- NCAP_PUUME

UniProt

P41268 - NCAP_PUUME

Protein

Nucleoprotein

Gene

N

Organism
Puumala virus (strain Evo/12CG/93)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 44 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Encapsidates the genome protecting it from nucleases. The encapsidated genomic RNA is termed the nucleocapsid (NC) and serves as template for transcription and replication By similarity.By similarity

    GO - Molecular functioni

    1. RNA binding Source: UniProtKB-KW

    Keywords - Molecular functioni

    Ribonucleoprotein

    Keywords - Ligandi

    RNA-binding, Viral nucleoprotein

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleoprotein
    Alternative name(s):
    Nucleocapsid protein
    Short name:
    Protein N
    Gene namesi
    Name:N
    OrganismiPuumala virus (strain Evo/12CG/93)
    Taxonomic identifieri38999 [NCBI]
    Taxonomic lineageiVirusesssRNA negative-strand virusesBunyaviridaeHantavirus
    Virus hostiHomo sapiens (Human) [TaxID: 9606]
    Myodes glareolus (Bank vole) (Clethrionomys glareolus) [TaxID: 447135]

    Subcellular locationi

    Virion
    Note: Internal protein of virus particle.

    GO - Cellular componenti

    1. helical viral capsid Source: UniProtKB-KW
    2. ribonucleoprotein complex Source: UniProtKB-KW
    3. viral nucleocapsid Source: UniProtKB-KW

    Keywords - Cellular componenti

    Capsid protein, Helical capsid protein, Virion

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 433433NucleoproteinPRO_0000222012Add
    BLAST

    Structurei

    3D structure databases

    ProteinModelPortaliP41268.
    SMRiP41268. Positions 1-74.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Family and domain databases

    InterProiIPR002214. Hanta_nucleocap.
    [Graphical view]
    PfamiPF00846. Hanta_nucleocap. 1 hit.
    [Graphical view]
    PIRSFiPIRSF003949. N_HantaV. 1 hit.
    ProDomiPD001501. Hanta_nucleocap. 1 hit.
    [Graphical view] [Entries sharing at least one domain]

    Sequencei

    Sequence statusi: Complete.

    P41268-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSDLTDIQED ITRHEQQLVV ARQKLKDAER AVEVDPDDVN KNTLQARQQT    50
    VSALEDKLAD YKRRMADAVS RKKMDTKPTD PTGIEPDDHL KERSSLRYGN 100
    VLDVNAIDIE EPSGQTADWY TIGVYVIGFT IPIILKALYM LSTRGRQTVK 150
    ENKGTRIRFK DDTSFEDING IRRPKHLYVS MPTAQSTMKA EELTPGRFRT 200
    IVCGLFPTQI QVRNIMSPVM GVIGFSFFVK DWPERIREFM EKECPFIKPE 250
    IKPGTPAQEM EMLKRNKIYF MQRQDVLDKN HVADIDKLID YAASGDPTSP 300
    DNIDSPNAPW VFACAPDRCP PTCIYVAGMA ELGAFFSILQ DMRNTIMASK 350
    TVGTAEEKLR KKSSFYQSYL RRTQSMGIQL DQRIILLFML EWGKEMVDHF 400
    HLGDDMDPEL RGLAQALIDQ KVKEISNQEP LKI 433
    Length:433
    Mass (Da):49,508
    Last modified:February 1, 1995 - v1
    Checksum:iEF2B4DF273132F93
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z30703 Genomic RNA. Translation: CAA83188.1.
    Z30702 Genomic RNA. Translation: CAA83187.1.
    PIRiS43008.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z30703 Genomic RNA. Translation: CAA83188.1 .
    Z30702 Genomic RNA. Translation: CAA83187.1 .
    PIRi S43008.

    3D structure databases

    ProteinModelPortali P41268.
    SMRi P41268. Positions 1-74.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Family and domain databases

    InterProi IPR002214. Hanta_nucleocap.
    [Graphical view ]
    Pfami PF00846. Hanta_nucleocap. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF003949. N_HantaV. 1 hit.
    ProDomi PD001501. Hanta_nucleocap. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    ProtoNeti Search...

    Publicationsi

    1. "Genetic variation of wild Puumala viruses within the serotype, local rodent populations and individual animal."
      Plyusnin A., Vapalahti O., Lehvaeslaiho H., Apekina N., Mikhailova T., Gavilovskaya I., Laakkonen J., Niemimaa J., Henttonen H., Brummer-Korvenkontio M., Vaheri A.
      Virus Res. 38:25-41(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC RNA].

    Entry informationi

    Entry nameiNCAP_PUUME
    AccessioniPrimary (citable) accession number: P41268
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 44 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programViral Protein Annotation Program

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3