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P41233

- ABCA1_MOUSE

UniProt

P41233 - ABCA1_MOUSE

Protein

ATP-binding cassette sub-family A member 1

Gene

Abca1

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 144 (01 Oct 2014)
      Sequence version 4 (27 Jul 2011)
      Previous versions | rss
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    Functioni

    cAMP-dependent and sulfonylurea-sensitive anion transporter. Key gatekeeper influencing intracellular cholesterol transport By similarity.By similarity

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi933 – 9408ATP 1PROSITE-ProRule annotation
    Nucleotide bindingi1946 – 19538ATP 2PROSITE-ProRule annotation

    GO - Molecular functioni

    1. anion transmembrane transporter activity Source: BHF-UCL
    2. apolipoprotein A-I receptor activity Source: Ensembl
    3. ATPase activity Source: InterPro
    4. ATP binding Source: UniProtKB-KW
    5. cholesterol transporter activity Source: MGI
    6. phospholipid transporter activity Source: MGI
    7. protein binding Source: MGI

    GO - Biological processi

    1. cellular response to cholesterol Source: Ensembl
    2. cellular response to lipopolysaccharide Source: UniProtKB
    3. cellular response to retinoic acid Source: UniProtKB
    4. cholesterol efflux Source: MGI
    5. cholesterol homeostasis Source: Ensembl
    6. cholesterol metabolic process Source: MGI
    7. endosomal transport Source: Ensembl
    8. G-protein coupled receptor signaling pathway Source: Ensembl
    9. high-density lipoprotein particle assembly Source: Ensembl
    10. interleukin-1 beta secretion Source: Ensembl
    11. intracellular cholesterol transport Source: Ensembl
    12. lipoprotein biosynthetic process Source: MGI
    13. lipoprotein metabolic process Source: MGI
    14. lysosome organization Source: Ensembl
    15. peptide secretion Source: MGI
    16. phagocytosis, engulfment Source: MGI
    17. phospholipid efflux Source: MGI
    18. phospholipid homeostasis Source: Ensembl
    19. phospholipid translocation Source: MGI
    20. platelet dense granule organization Source: Ensembl
    21. positive regulation of cAMP biosynthetic process Source: Ensembl
    22. positive regulation of cholesterol efflux Source: BHF-UCL
    23. protein lipidation Source: MGI
    24. regulation of Cdc42 protein signal transduction Source: Ensembl
    25. response to drug Source: Ensembl
    26. response to laminar fluid shear stress Source: Ensembl
    27. response to low-density lipoprotein particle Source: Ensembl
    28. response to nutrient Source: Ensembl
    29. reverse cholesterol transport Source: BHF-UCL

    Keywords - Biological processi

    Transport

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    ReactomeiREACT_198602. PPARA activates gene expression.
    REACT_213857. HDL-mediated lipid transport.

    Protein family/group databases

    TCDBi3.A.1.211.1. the atp-binding cassette (abc) superfamily.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    ATP-binding cassette sub-family A member 1
    Alternative name(s):
    ATP-binding cassette transporter 1
    Short name:
    ABC-1
    Short name:
    ATP-binding cassette 1
    Gene namesi
    Name:Abca1
    Synonyms:Abc1
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 4

    Organism-specific databases

    MGIiMGI:99607. Abca1.

    Subcellular locationi

    GO - Cellular componenti

    1. external side of plasma membrane Source: MGI
    2. Golgi apparatus Source: MGI
    3. integral component of plasma membrane Source: MGI
    4. intracellular membrane-bounded organelle Source: MGI
    5. membrane raft Source: Ensembl
    6. phagocytic vesicle Source: Ensembl
    7. plasma membrane Source: MGI

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 22612261ATP-binding cassette sub-family A member 1PRO_0000093289Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Lipidationi3 – 31S-palmitoyl cysteineBy similarity
    Glycosylationi14 – 141N-linked (GlcNAc...)Sequence Analysis
    Lipidationi23 – 231S-palmitoyl cysteineBy similarity
    Disulfide bondi75 ↔ 309By similarity
    Glycosylationi98 – 981N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi151 – 1511N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi161 – 1611N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi196 – 1961N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi244 – 2441N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi292 – 2921N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi337 – 3371N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi349 – 3491N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi400 – 4001N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi478 – 4781N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi489 – 4891N-linked (GlcNAc...)1 Publication
    Glycosylationi521 – 5211N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi820 – 8201N-linked (GlcNAc...)Sequence Analysis
    Modified residuei1042 – 10421Phosphoserine; by PKABy similarity
    Lipidationi1110 – 11101S-palmitoyl cysteineBy similarity
    Lipidationi1111 – 11111S-palmitoyl cysteineBy similarity
    Glycosylationi1144 – 11441N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1294 – 12941N-linked (GlcNAc...)Sequence Analysis
    Modified residuei1296 – 12961Phosphoserine1 Publication
    Glycosylationi1453 – 14531N-linked (GlcNAc...)Sequence Analysis
    Disulfide bondi1463 ↔ 1477By similarity
    Glycosylationi1499 – 14991N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1504 – 15041N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi1637 – 16371N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi2044 – 20441N-linked (GlcNAc...)Sequence Analysis
    Modified residuei2054 – 20541Phosphoserine; by PKABy similarity
    Glycosylationi2238 – 22381N-linked (GlcNAc...)Sequence Analysis

    Post-translational modificationi

    Phosphorylation on Ser-2054 regulates phospholipid efflux.By similarity
    Palmitoylation by DHHC8 is essential for membrane localization.By similarity

    Keywords - PTMi

    Disulfide bond, Glycoprotein, Lipoprotein, Palmitate, Phosphoprotein

    Proteomic databases

    MaxQBiP41233.
    PaxDbiP41233.
    PRIDEiP41233.

    PTM databases

    PhosphoSiteiP41233.

    Miscellaneous databases

    PMAP-CutDBB1AWZ8.

    Expressioni

    Tissue specificityi

    Widely expressed in adult tissues. Highest levels are found in pregnant uterus and uterus.

    Inductioni

    Down-regulated by endotoxins (LPS) or cytokines (TNF and IL-1) in J774 macrophages. The down-regulation by endotoxin in macrophages is not likely to be mediated by the liver X receptor/retinoic X receptor (LXR/RXR).1 Publication

    Gene expression databases

    BgeeiP41233.
    GenevestigatoriP41233.

    Interactioni

    Subunit structurei

    Interacts with MEGF10.1 Publication

    Protein-protein interaction databases

    BioGridi197900. 2 interactions.
    IntActiP41233. 2 interactions.
    STRINGi10090.ENSMUSP00000030010.

    Structurei

    3D structure databases

    ProteinModelPortaliP41233.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini43 – 639597ExtracellularBy similarityAdd
    BLAST
    Topological domaini1372 – 1656285ExtracellularBy similarityAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei22 – 4221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei640 – 66021HelicalSequence AnalysisAdd
    BLAST
    Transmembranei683 – 70321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei716 – 73621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei745 – 76521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei777 – 79721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei827 – 84721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei941 – 96121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1351 – 137121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1657 – 167721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1703 – 172321HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1735 – 175521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1768 – 178821HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1802 – 182221HelicalSequence AnalysisAdd
    BLAST
    Transmembranei1852 – 187221HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini899 – 1131233ABC transporter 1PROSITE-ProRule annotationAdd
    BLAST
    Domaini1912 – 2144233ABC transporter 2PROSITE-ProRule annotationAdd
    BLAST

    Domaini

    Multifunctional polypeptide with two homologous halves, each containing a hydrophobic membrane-anchoring domain and an ATP binding cassette (ABC) domain.

    Sequence similaritiesi

    Contains 2 ABC transporter domains.PROSITE-ProRule annotation

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1131.
    GeneTreeiENSGT00720000108414.
    HOGENOMiHOG000231547.
    HOVERGENiHBG050436.
    InParanoidiB1AWZ8.
    KOiK05641.
    OMAiFSMRSWS.
    OrthoDBiEOG78D7J6.
    TreeFamiTF105191.

    Family and domain databases

    Gene3Di3.40.50.300. 2 hits.
    InterProiIPR003593. AAA+_ATPase.
    IPR026082. ABC_A.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view]
    PANTHERiPTHR19229. PTHR19229. 1 hit.
    PfamiPF00005. ABC_tran. 2 hits.
    [Graphical view]
    SMARTiSM00382. AAA. 2 hits.
    [Graphical view]
    SUPFAMiSSF52540. SSF52540. 2 hits.
    PROSITEiPS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P41233-1 [UniParc]FASTAAdd to Basket

    « Hide

    MACWPQLRLL LWKNLTFRRR QTCQLLLEVA WPLFIFLILI SVRLSYPPYE     50
    QHECHFPNKA MPSAGTLPWV QGIICNANNP CFRYPTPGEA PGVVGNFNKS 100
    IVSRLFSDAQ RLLLYSQRDT SIKDMHKVLR MLRQIKHPNS NLKLQDFLVD 150
    NETFSGFLQH NLSLPRSTVD SLLQANVGLQ KVFLQGYQLH LASLCNGSKL 200
    EEIIQLGDAE VSALCGLPRK KLDAAERVLR YNMDILKPVV TKLNSTSHLP 250
    TQHLAEATTV LLDSLGGLAQ ELFSTKSWSD MRQEVMFLTN VNSSSSSTQI 300
    YQAVSRIVCG HPEGGGLKIK SLNWYEDNNY KALFGGNNTE EDVDTFYDNS 350
    TTPYCNDLMK NLESSPLSRI IWKALKPLLV GKILYTPDTP ATRQVMAEVN 400
    KTFQELAVFH DLEGMWEELS PQIWTFMENS QEMDLVRTLL DSRGNDQFWE 450
    QKLDGLDWTA QDIMAFLAKN PEDVQSPNGS VYTWREAFNE TNQAIQTISR 500
    FMECVNLNKL EPIPTEVRLI NKSMELLDER KFWAGIVFTG ITPDSVELPH 550
    HVKYKIRMDI DNVERTNKIK DGYWDPGPRA DPFEDMRYVW GGFAYLQDVV 600
    EQAIIRVLTG SEKKTGVYVQ QMPYPCYVDD IFLRVMSRSM PLFMTLAWIY 650
    SVAVIIKSIV YEKEARLKET MRIMGLDNGI LWFSWFVSSL IPLLVSAGLL 700
    VVILKLGNLL PYSDPSVVFV FLSVFAMVTI LQCFLISTLF SRANLAAACG 750
    GIIYFTLYLP YVLCVAWQDY VGFSIKIFAS LLSPVAFGFG CEYFALFEEQ 800
    GIGVQWDNLF ESPVEEDGFN LTTAVSMMLF DTFLYGVMTW YIEAVFPGQY 850
    GIPRPWYFPC TKSYWFGEEI DEKSHPGSSQ KGVSEICMEE EPTHLRLGVS 900
    IQNLVKVYRD GMKVAVDGLA LNFYEGQITS FLGHNGAGKT TTMSILTGLF 950
    PPTSGTAYIL GKDIRSEMSS IRQNLGVCPQ HNVLFDMLTV EEHIWFYARL 1000
    KGLSEKHVKA EMEQMALDVG LPPSKLKSKT SQLSGGMQRK LSVALAFVGG 1050
    SKVVILDEPT AGVDPYSRRG IWELLLKYRQ GRTIILSTHH MDEADILGDR 1100
    IAIISHGKLC CVGSSLFLKN QLGTGYYLTL VKKDVESSLS SCRNSSSTVS 1150
    CLKKEDSVSQ SSSDAGLGSD HESDTLTIDV SAISNLIRKH VSEARLVEDI 1200
    GHELTYVLPY EAAKEGAFVE LFHEIDDRLS DLGISSYGIS ETTLEEIFLK 1250
    VAEESGVDAE TSDGTLPARR NRRAFGDKQS CLHPFTEDDA VDPNDSDIDP 1300
    ESRETDLLSG MDGKGSYQLK GWKLTQQQFV ALLWKRLLIA RRSRKGFFAQ 1350
    IVLPAVFVCI ALVFSLIVPP FGKYPSLELQ PWMYNEQYTF VSNDAPEDMG 1400
    TQELLNALTK DPGFGTRCME GNPIPDTPCL AGEEDWTISP VPQSIVDLFQ 1450
    NGNWTMKNPS PACQCSSDKI KKMLPVCPPG AGGLPPPQRK QKTADILQNL 1500
    TGRNISDYLV KTYVQIIAKS LKNKIWVNEF RYGGFSLGVS NSQALPPSHE 1550
    VNDAIKQMKK LLKLTKDSSA DRFLSSLGRF MAGLDTKNNV KVWFNNKGWH 1600
    AISSFLNVIN NAILRANLQK GENPSQYGIT AFNHPLNLTK QQLSEVALMT 1650
    TSVDVLVSIC VIFAMSFVPA SFVVFLIQER VSKAKHLQFI SGVKPVIYWL 1700
    SNFVWDMCNY VVPATLVIII FICFQQKSYV SSTNLPVLAL LLLLYGWSIT 1750
    PLMYPASFVF KIPSTAYVVL TSVNLFIGIN GSVATFVLEL FTNNKLNDIN 1800
    DILKSVFLIF PHFCLGRGLI DMVKNQAMAD ALERFGENRF VSPLSWDLVG 1850
    RNLFAMAVEG VVFFLITVLI QYRFFIRPRP VKAKLPPLND EDEDVRRERQ 1900
    RILDGGGQND ILEIKELTKI YRRKRKPAVD RICIGIPPGE CFGLLGVNGA 1950
    GKSTTFKMLT GDTPVTRGDA FLNKNSILSN IHEVHQNMGY CPQFDAITEL 2000
    LTGREHVEFF ALLRGVPEKE VGKVGEWAIR KLGLVKYGEK YASNYSGGNK 2050
    RKLSTAMALI GGPPVVFLDE PTTGMDPKAR RFLWNCALSI VKEGRSVVLT 2100
    SHSMEECEAL CTRMAIMVNG RFRCLGSVQH LKNRFGDGYT IVVRIAGSNP 2150
    DLKPVQEFFG LAFPGSVLKE KHRNMLQYQL PSSLSSLARI FSILSQSKKR 2200
    LHIEDYSVSQ TTLDQVFVNF AKDQSDDDHL KDLSLHKNQT VVDVAVLTSF 2250
    LQDEKVKESY V 2261
    Length:2,261
    Mass (Da):253,912
    Last modified:July 27, 2011 - v4
    Checksum:iE041DA4FA73C2660
    GO

    Sequence cautioni

    The sequence AAG39073.1 differs from that shown. Reason: Erroneous initiation.
    The sequence CAA53530.1 differs from that shown. Reason: Erroneous initiation.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti1567 – 15682Missing in AAG39073. (PubMed:11352567)Curated
    Sequence conflicti1568 – 15681S → T in CAA53530. (PubMed:8088782)Curated
    Sequence conflicti2024 – 20241V → F in CAA53530. (PubMed:8088782)Curated
    Sequence conflicti2024 – 20241Missing in AAG39073. (PubMed:11352567)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75926 mRNA. Translation: CAA53530.1. Different initiation.
    AF287263 Genomic DNA. Translation: AAG39073.1. Different initiation.
    AL807243, AL772397 Genomic DNA. Translation: CAM18883.1.
    AL772397, AL807243 Genomic DNA. Translation: CAM27437.1.
    CH466565 Genomic DNA. Translation: EDL02285.1.
    CCDSiCCDS18187.1.
    PIRiA54774.
    RefSeqiNP_038482.3. NM_013454.3.
    UniGeneiMm.277376.

    Genome annotation databases

    EnsembliENSMUST00000030010; ENSMUSP00000030010; ENSMUSG00000015243.
    GeneIDi11303.
    KEGGimmu:11303.
    UCSCiuc008swu.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X75926 mRNA. Translation: CAA53530.1 . Different initiation.
    AF287263 Genomic DNA. Translation: AAG39073.1 . Different initiation.
    AL807243 , AL772397 Genomic DNA. Translation: CAM18883.1 .
    AL772397 , AL807243 Genomic DNA. Translation: CAM27437.1 .
    CH466565 Genomic DNA. Translation: EDL02285.1 .
    CCDSi CCDS18187.1.
    PIRi A54774.
    RefSeqi NP_038482.3. NM_013454.3.
    UniGenei Mm.277376.

    3D structure databases

    ProteinModelPortali P41233.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 197900. 2 interactions.
    IntActi P41233. 2 interactions.
    STRINGi 10090.ENSMUSP00000030010.

    Chemistry

    ChEMBLi CHEMBL1641361.

    Protein family/group databases

    TCDBi 3.A.1.211.1. the atp-binding cassette (abc) superfamily.

    PTM databases

    PhosphoSitei P41233.

    Proteomic databases

    MaxQBi P41233.
    PaxDbi P41233.
    PRIDEi P41233.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000030010 ; ENSMUSP00000030010 ; ENSMUSG00000015243 .
    GeneIDi 11303.
    KEGGi mmu:11303.
    UCSCi uc008swu.1. mouse.

    Organism-specific databases

    CTDi 19.
    MGIi MGI:99607. Abca1.

    Phylogenomic databases

    eggNOGi COG1131.
    GeneTreei ENSGT00720000108414.
    HOGENOMi HOG000231547.
    HOVERGENi HBG050436.
    InParanoidi B1AWZ8.
    KOi K05641.
    OMAi FSMRSWS.
    OrthoDBi EOG78D7J6.
    TreeFami TF105191.

    Enzyme and pathway databases

    Reactomei REACT_198602. PPARA activates gene expression.
    REACT_213857. HDL-mediated lipid transport.

    Miscellaneous databases

    NextBioi 278586.
    PMAP-CutDB B1AWZ8.
    PROi P41233.
    SOURCEi Search...

    Gene expression databases

    Bgeei P41233.
    Genevestigatori P41233.

    Family and domain databases

    Gene3Di 3.40.50.300. 2 hits.
    InterProi IPR003593. AAA+_ATPase.
    IPR026082. ABC_A.
    IPR003439. ABC_transporter-like.
    IPR017871. ABC_transporter_CS.
    IPR027417. P-loop_NTPase.
    [Graphical view ]
    PANTHERi PTHR19229. PTHR19229. 1 hit.
    Pfami PF00005. ABC_tran. 2 hits.
    [Graphical view ]
    SMARTi SM00382. AAA. 2 hits.
    [Graphical view ]
    SUPFAMi SSF52540. SSF52540. 2 hits.
    PROSITEi PS00211. ABC_TRANSPORTER_1. 1 hit.
    PS50893. ABC_TRANSPORTER_2. 2 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Cloning of two novel ABC transporters mapping on human chromosome 9."
      Luciani M.-F., Denizot F., Savary S., Mattei M.-G., Chimini G.
      Genomics 21:150-159(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: DBA/2.
      Tissue: Macrophage.
    2. "Human and mouse ABCA1 comparative sequencing and transgenesis studies revealing novel regulatory sequences."
      Qiu Y., Cavelier L., Chiu S., Yang X., Rubin E., Cheng J.-F.
      Genomics 73:66-76(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: C57BL/6J.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: C57BL/6J.
    4. Mural R.J., Adams M.D., Myers E.W., Smith H.O., Venter J.C.
      Submitted (SEP-2005) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    5. "Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway."
      Kaplan R., Gan X., Menke J.G., Wright S.D., Cai T.-Q.
      J. Lipid Res. 43:952-959(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INDUCTION BY LIPOPOLYSACCHARIDE.
    6. "Endotoxin down-regulates ABCG5 and ABCG8 in mouse liver and ABCA1 and ABCG1 in J774 murine macrophages: differential role of LXR."
      Khovidhunkit W., Moser A.H., Shigenaga J.K., Grunfeld C., Feingold K.R.
      J. Lipid Res. 44:1728-1736(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: DOWN-REGULATION BY ENDOTOXIN.
    7. "Cooperation between engulfment receptors: the case of ABCA1 and MEGF10."
      Hamon Y., Trompier D., Ma Z., Venegas V., Pophillat M., Mignotte V., Zhou Z., Chimini G.
      PLoS ONE 1:E120-E120(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH MEGF10.
    8. Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-1296, IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
      Tissue: Liver.
    9. "Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins."
      Wollscheid B., Bausch-Fluck D., Henderson C., O'Brien R., Bibel M., Schiess R., Aebersold R., Watts J.D.
      Nat. Biotechnol. 27:378-386(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: GLYCOSYLATION [LARGE SCALE ANALYSIS] AT ASN-489.

    Entry informationi

    Entry nameiABCA1_MOUSE
    AccessioniPrimary (citable) accession number: P41233
    Secondary accession number(s): B1AWZ8
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: July 27, 2011
    Last modified: October 1, 2014
    This is version 144 of the entry and version 4 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3