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P41230

- KDM5C_MOUSE

UniProt

P41230 - KDM5C_MOUSE

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Protein

Lysine-specific demethylase 5C

Gene
Kdm5c, Jarid1c, Kiaa0234, Smcx, Xe169
Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 5 out of 5 - Experimental evidence at transcript leveli

Functioni

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. Participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements By similarity.1 Publication

Cofactori

Alpha-ketoglutarate By similarity.
Binds 1 Fe2+ ion per subunit By similarity.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi514 – 5141Iron; catalytic By similarity
Metal bindingi517 – 5171Iron; catalytic By similarity
Metal bindingi602 – 6021Iron; catalytic By similarity

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Zinc fingeri326 – 37247PHD-type 1Add
BLAST
Zinc fingeri1187 – 124862PHD-type 2Add
BLAST

GO - Molecular functioni

  1. DNA binding Source: InterPro
  2. histone demethylase activity (H3-K4 specific) Source: Ensembl
  3. oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors Source: InterPro
  4. zinc ion binding Source: InterPro

GO - Biological processi

  1. regulation of transcription, DNA-templated Source: UniProtKB-KW
  2. transcription, DNA-templated Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Chromatin regulator, Dioxygenase, Oxidoreductase

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

Iron, Metal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Lysine-specific demethylase 5C (EC:1.14.11.-)
Alternative name(s):
Histone demethylase JARID1C
Jumonji/ARID domain-containing protein 1C
Protein SmcX
Protein Xe169
Gene namesi
Name:Kdm5c
Synonyms:Jarid1c, Kiaa0234, Smcx, Xe169
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
ProteomesiUP000000589: Chromosome X

Organism-specific databases

MGIiMGI:99781. Kdm5c.

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 15541554Lysine-specific demethylase 5CPRO_0000200587Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei317 – 3171Phosphoserine By similarity
Modified residuei1353 – 13531Phosphoserine By similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP41230.
PaxDbiP41230.
PRIDEiP41230.

PTM databases

PhosphoSiteiP41230.

Expressioni

Gene expression databases

ArrayExpressiP41230.
BgeeiP41230.
GenevestigatoriP41230.

Interactioni

Subunit structurei

Part of two distinct complexes, one containing E2F6, and the other containing REST By similarity.

Protein-protein interaction databases

BioGridi203341. 2 interactions.

Structurei

3D structure databases

ProteinModelPortaliP41230.
SMRiP41230. Positions 13-188, 261-616, 1187-1254.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini14 – 5542JmjNAdd
BLAST
Domaini79 – 16991ARIDAdd
BLAST
Domaini468 – 634167JmjCAdd
BLAST

Domaini

The first PHD-type zinc finger domain recognizes and binds H3-K9Me3 By similarity.
Both the JmjC domain and the JmjN domain are required for enzymatic activity By similarity.

Sequence similaritiesi

Contains 1 ARID domain.
Contains 1 JmjC domain.
Contains 1 JmjN domain.

Keywords - Domaini

Repeat, Zinc-finger

Phylogenomic databases

eggNOGiNOG327026.
GeneTreeiENSGT00530000063118.
InParanoidiP41230.
KOiK11446.
OMAiTTSICVC.
OrthoDBiEOG7D85VK.
PhylomeDBiP41230.
TreeFamiTF106476.

Family and domain databases

Gene3Di1.10.150.60. 1 hit.
3.30.40.10. 2 hits.
InterProiIPR001606. ARID/BRIGHT_DNA-bd.
IPR003347. JmjC_dom.
IPR013637. Lys_sp_deMease_like_dom.
IPR003349. TF_JmjN.
IPR019786. Zinc_finger_PHD-type_CS.
IPR004198. Znf_C5HC2.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view]
PfamiPF01388. ARID. 1 hit.
PF02373. JmjC. 1 hit.
PF02375. JmjN. 1 hit.
PF00628. PHD. 1 hit.
PF08429. PLU-1. 1 hit.
PF02928. zf-C5HC2. 1 hit.
[Graphical view]
SMARTiSM00501. BRIGHT. 1 hit.
SM00558. JmjC. 1 hit.
SM00545. JmjN. 1 hit.
SM00249. PHD. 2 hits.
[Graphical view]
SUPFAMiSSF46774. SSF46774. 1 hit.
SSF57903. SSF57903. 2 hits.
PROSITEiPS51011. ARID. 1 hit.
PS51184. JMJC. 1 hit.
PS51183. JMJN. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view]

Sequences (3)i

Sequence statusi: Complete.

This entry describes 3 isoformsi produced by alternative splicing. Align

Isoform 1 (identifier: P41230-1) [UniParc]FASTAAdd to Basket

This isoform has been chosen as the 'canonical' sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide

MELGSDDFLP PPECPVFEPS WAEFRDPLGY IAKIRPIAEK SGICKIRPPA     50
DWQPPFAVEV DNFRFTPRIQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL 100
KIPNVERRIL DLYSLSKIVV EEGGYETICK DRRWARVAQR LNYPPGKNIG 150
SLLRSHYERI VYPYEMYQSG ANLVQCNTRP FDNEEKDKEY KPHSIPLRQS 200
VQPSKFNSYG RRAKRLQPDP EPTEEDIEKN PELKKLQIYG AGPKMMGLGL 250
MAKDKTLRKK DKEGPECPPT VVVKEELGGD VKMESTSPKT FLEGKEELSH 300
SPEPCTKMTM RLRRNHSNAQ FIESYVCRMC SRGDEDDKLL LCDGCDDNYH 350
IFCLLPPLPE IPKGVWRCPK CVMAECKRPP EAFGFEQATR EYTLQSFGEM 400
ADSFKADYFN MPVHMVPTEL VEKEFWRLVN SIEEDVTVEY GADIHSKEFG 450
SGFPVSDSKR HLTPEEEEYA TSGWNLNVMP VLEQSVLCHI NADISGMKVP 500
WLYVGMVFSA FCWHIEDHWS YSINYLHWGE PKTWYGVPSL AAEHLEEVMK 550
KLTPELFDSQ PDLLHQLVTL MNPNTLMSHG VPVVRTNQCA GEFVITFPRA 600
YHSGFNQGYN FAEAVNFCTA DWLPAGRQCI EHYRRLRRYC VFSHEELICK 650
MAACPEKLDL NLAAAVHKEM FIMVQEERRL RKALLEKGIT EAEREAFELL 700
PDDERQCIKC KTTCFLSALA CYDCPDGLVC LSHINDLCKC SSSRQYLRYR 750
YTLDELPAML HKLKVRAESF DTWANKVRVA LEVEDGRKRS LEELRALESE 800
ARERRFPNSE LLQRLKNCLS EAEACVSRAL GLVSGQEAGP DRVAGLQMTL 850
AELRDFLGQM NNLPCAMHQI GDVKGILEQV EAYQTEAREA LVSQPSSPGL 900
LQSLLERGQQ LGVEVPEAQQ LQRQVEQARW LDEVKRTLAP SARRGTLAIM 950
RGLLVAGASV APSPAVDKAQ AELQELLTIA ERWEEKAHLC LEARQKHPPA 1000
TLEAIIHEAE NIPVHLPNIQ SLKEALAKAR AWIADVDEIQ NGDHYPCLDD 1050
LEGLVAVGRD LPVGLEELRQ LELQVLTAHS WREKASKTFL KKNSCYTLLE 1100
VLCPCADAGS DSTKRSRWME KELGLYKSDT ELLGLSAQDL RDPGSVIVAF 1150
KEGEQKEKEG ILQLRRTNSA KPSPLALLTT ASSTASICVC GQVPAGVGAL 1200
QCDLCQDWFH GRCVTVPRLL SSQRSSLPSS PLLAWWEWDT KFLCPLCMRS 1250
RRPRLETILA LLVALQRLPV RLPEGEALQC LTERAISWQG RARQVLASEE 1300
VTALLGRLAE LRQRLQAESK PEESLAYPSD GGEGTGNMPK VQGLLENGDS 1350
VTSPEKVATE EGSGKRDLEL LSSILPQLSG PVLELPEATR APLEELMMEG 1400
DLLEVTLDEN HSIWQLLQAG QPPDLKRVQT LLELEKAERH GSRTRGRALE 1450
RRRRRKVDRG GEPDDPAREE LEPKRVRSSG PEAEEVQEEE ELEEETGGEV 1500
PPVPFPNSGS PSIQEDQDGL EPVLEAGSDT SAPFSTLTSR LLMSCPQQPS 1550
LQQL 1554
Length:1,554
Mass (Da):175,313
Last modified:June 26, 2007 - v4
Checksum:i585EA9F890B0D9A0
GO
Isoform 2 (identifier: P41230-2) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     1364-1366: Missing.

Show »
Length:1,551
Mass (Da):174,972
Checksum:iC2061676EA2DC238
GO
Isoform 3 (identifier: P41230-3) [UniParc]FASTAAdd to Basket

The sequence of this isoform differs from the canonical sequence as follows:
     77-117: Missing.
     1364-1366: Missing.

Show »
Length:1,510
Mass (Da):170,154
Checksum:iBAA3698F0A0A1E24
GO

Alternative sequence

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Alternative sequencei77 – 11741Missing in isoform 3. VSP_026411Add
BLAST
Alternative sequencei1364 – 13663Missing in isoform 2 and isoform 3. VSP_000316

Sequence conflict

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti3 – 31L → M in AAB96762. 1 Publication
Sequence conflicti26 – 261D → G in AAB96762. 1 Publication
Sequence conflicti123 – 1231G → S in BAE33161. 1 Publication
Sequence conflicti123 – 1231G → S in BAE33260. 1 Publication
Sequence conflicti249 – 2491G → D in BAE34464. 1 Publication
Sequence conflicti726 – 7261D → N in BAC97906. 1 Publication
Sequence conflicti865 – 8651C → L in AAD53049. 1 Publication
Sequence conflicti865 – 8651C → L in CAA82759. 1 Publication
Sequence conflicti1068 – 10681L → P in CAA82759. 1 Publication
Sequence conflicti1126 – 11261Y → C in BAE33367. 1 Publication

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF127245 mRNA. Translation: AAD53049.1.
AK008105 mRNA. Translation: BAB25462.1.
AK155279 mRNA. Translation: BAE33161.1.
AK155427 mRNA. Translation: BAE33260.1.
AK155651 mRNA. Translation: BAE33367.1.
AK158340 mRNA. Translation: BAE34464.1.
AK011577 mRNA. No translation available.
BC043096 mRNA. Translation: AAH43096.1.
BC054550 mRNA. Translation: AAH54550.1.
Z29651 mRNA. Translation: CAA82759.1.
AK129096 mRNA. Translation: BAC97906.1.
L29563 mRNA. Translation: AAA62384.1.
AF039894 mRNA. Translation: AAB96762.1.
CCDSiCCDS41178.1. [P41230-2]
PIRiI48775.
I84689.
RefSeqiNP_038696.2. NM_013668.4. [P41230-2]
XP_006528832.1. XM_006528769.1. [P41230-1]
XP_006528835.1. XM_006528772.1. [P41230-3]
UniGeneiMm.142655.
Mm.482277.

Genome annotation databases

EnsembliENSMUST00000082177; ENSMUSP00000080814; ENSMUSG00000025332. [P41230-3]
ENSMUST00000112584; ENSMUSP00000108203; ENSMUSG00000025332. [P41230-1]
ENSMUST00000112588; ENSMUSP00000108207; ENSMUSG00000025332. [P41230-2]
GeneIDi20591.
KEGGimmu:20591.
UCSCiuc009uqc.2. mouse. [P41230-2]
uc009uqd.2. mouse. [P41230-3]
uc009uqe.2. mouse. [P41230-1]

Keywords - Coding sequence diversityi

Alternative splicing

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AF127245 mRNA. Translation: AAD53049.1 .
AK008105 mRNA. Translation: BAB25462.1 .
AK155279 mRNA. Translation: BAE33161.1 .
AK155427 mRNA. Translation: BAE33260.1 .
AK155651 mRNA. Translation: BAE33367.1 .
AK158340 mRNA. Translation: BAE34464.1 .
AK011577 mRNA. No translation available.
BC043096 mRNA. Translation: AAH43096.1 .
BC054550 mRNA. Translation: AAH54550.1 .
Z29651 mRNA. Translation: CAA82759.1 .
AK129096 mRNA. Translation: BAC97906.1 .
L29563 mRNA. Translation: AAA62384.1 .
AF039894 mRNA. Translation: AAB96762.1 .
CCDSi CCDS41178.1. [P41230-2 ]
PIRi I48775.
I84689.
RefSeqi NP_038696.2. NM_013668.4. [P41230-2 ]
XP_006528832.1. XM_006528769.1. [P41230-1 ]
XP_006528835.1. XM_006528772.1. [P41230-3 ]
UniGenei Mm.142655.
Mm.482277.

3D structure databases

ProteinModelPortali P41230.
SMRi P41230. Positions 13-188, 261-616, 1187-1254.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

BioGridi 203341. 2 interactions.

PTM databases

PhosphoSitei P41230.

Proteomic databases

MaxQBi P41230.
PaxDbi P41230.
PRIDEi P41230.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

Ensembli ENSMUST00000082177 ; ENSMUSP00000080814 ; ENSMUSG00000025332 . [P41230-3 ]
ENSMUST00000112584 ; ENSMUSP00000108203 ; ENSMUSG00000025332 . [P41230-1 ]
ENSMUST00000112588 ; ENSMUSP00000108207 ; ENSMUSG00000025332 . [P41230-2 ]
GeneIDi 20591.
KEGGi mmu:20591.
UCSCi uc009uqc.2. mouse. [P41230-2 ]
uc009uqd.2. mouse. [P41230-3 ]
uc009uqe.2. mouse. [P41230-1 ]

Organism-specific databases

CTDi 8242.
MGIi MGI:99781. Kdm5c.
Rougei Search...

Phylogenomic databases

eggNOGi NOG327026.
GeneTreei ENSGT00530000063118.
InParanoidi P41230.
KOi K11446.
OMAi TTSICVC.
OrthoDBi EOG7D85VK.
PhylomeDBi P41230.
TreeFami TF106476.

Miscellaneous databases

ChiTaRSi KDM5C. mouse.
NextBioi 298901.
PROi P41230.
SOURCEi Search...

Gene expression databases

ArrayExpressi P41230.
Bgeei P41230.
Genevestigatori P41230.

Family and domain databases

Gene3Di 1.10.150.60. 1 hit.
3.30.40.10. 2 hits.
InterProi IPR001606. ARID/BRIGHT_DNA-bd.
IPR003347. JmjC_dom.
IPR013637. Lys_sp_deMease_like_dom.
IPR003349. TF_JmjN.
IPR019786. Zinc_finger_PHD-type_CS.
IPR004198. Znf_C5HC2.
IPR011011. Znf_FYVE_PHD.
IPR001965. Znf_PHD.
IPR019787. Znf_PHD-finger.
IPR013083. Znf_RING/FYVE/PHD.
[Graphical view ]
Pfami PF01388. ARID. 1 hit.
PF02373. JmjC. 1 hit.
PF02375. JmjN. 1 hit.
PF00628. PHD. 1 hit.
PF08429. PLU-1. 1 hit.
PF02928. zf-C5HC2. 1 hit.
[Graphical view ]
SMARTi SM00501. BRIGHT. 1 hit.
SM00558. JmjC. 1 hit.
SM00545. JmjN. 1 hit.
SM00249. PHD. 2 hits.
[Graphical view ]
SUPFAMi SSF46774. SSF46774. 1 hit.
SSF57903. SSF57903. 2 hits.
PROSITEi PS51011. ARID. 1 hit.
PS51184. JMJC. 1 hit.
PS51183. JMJN. 1 hit.
PS01359. ZF_PHD_1. 2 hits.
PS50016. ZF_PHD_2. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "Mouse H-Y encoding Smcy gene and its X chromosomal homolog Smcx."
    Agulnik A.I., Longepied G., Ty M.T., Bishop C.E., Mitchell M.J.
    Mamm. Genome 10:926-929(1999) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 2).
    Strain: 129/SvJ.
  2. "The transcriptional landscape of the mammalian genome."
    Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
    , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
    Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
    Strain: C57BL/6J and NOD.
    Tissue: Dendritic cell, Embryo, Inner ear and Small intestine.
  3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
    The MGC Project Team
    Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 3).
    Strain: C57BL/6.
    Tissue: Brain.
  4. "A novel X gene with a widely transcribed Y-linked homologue escapes X-inactivation in mouse and human."
    Agulnik A.I., Mitchell M.J., Mattei M.-G., Borsani G., Avner P.A., Lerner J.L., Bishop C.E.
    Hum. Mol. Genet. 3:879-884(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 36-1068.
    Strain: BALB/c.
    Tissue: Testis.
  5. "Prediction of the coding sequences of mouse homologues of KIAA gene: III. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries."
    Okazaki N., Kikuno R., Ohara R., Inamoto S., Koseki H., Hiraoka S., Saga Y., Nagase T., Ohara O., Koga H.
    DNA Res. 10:167-180(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 165-1554 (ISOFORM 1).
    Tissue: Embryonic tail.
  6. "The murine Xe169 gene escapes X-inactivation like its human homologue."
    Wu J., Salido E., Yen P., Mohandas T., Shapiro L.J.
    Nat. Genet. 7:491-496(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1206-1385 (ISOFORM 1).
  7. "A proposed path by which genes common to mammalian X and Y chromosomes evolve to become X inactivated."
    Jegalian K.G., Page D.C.
    Nature 394:776-780(1998) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-39.
  8. "Identification of a mouse male-specific transplantation antigen, H-Y."
    Scott D.M., Ehrmann I.E., Ellis P.S., Bishop C.E., Agulnik A.I., Simpson E., Mitchell M.J.
    Nature 376:695-698(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: FUNCTION.
    Strain: C3H.

Entry informationi

Entry nameiKDM5C_MOUSE
AccessioniPrimary (citable) accession number: P41230
Secondary accession number(s): O54995
, Q3TYU8, Q3U1X6, Q3U282, Q6ZQF8, Q80XQ9, Q9CVI4, Q9D0C3, Q9QVR8, Q9R039
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: June 26, 2007
Last modified: July 9, 2014
This is version 127 of the entry and version 4 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Miscellaneous

Escapes X-inactivation.

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi