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P41185 (RPOC_BUCAP) Reviewed, UniProtKB/Swiss-Prot

Last modified May 1, 2013. Version 85. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
DNA-directed RNA polymerase subunit beta'
Short name=RNAP subunit beta'
EC=2.7.7.6
Alternative name(s):
RNA polymerase subunit beta'
Transcriptase subunit beta'
Gene names
Name:rpoC
Ordered Locus Names:BUsg_034
OrganismBuchnera aphidicola subsp. Schizaphis graminum (strain Sg) [Complete proteome] [HAMAP]
Taxonomic identifier198804 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Buchnera ›

Protein attributes

Sequence length1413 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates By similarity. HAMAP-Rule MF_01322

Catalytic activity

Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1). HAMAP-Rule MF_01322

Subunit structure

The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription By similarity.

Sequence similarities

Belongs to the RNA polymerase beta' chain family.

Ontologies

Keywords
   Biological processTranscription
   Cellular componentDNA-directed RNA polymerase
   Molecular functionNucleotidyltransferase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processtranscription, DNA-dependent

Inferred from electronic annotation. Source: InterPro

   Molecular_functionDNA binding

Inferred from electronic annotation. Source: InterPro

DNA-directed RNA polymerase activity

Inferred from electronic annotation. Source: UniProtKB-KW

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 14131413DNA-directed RNA polymerase subunit beta' HAMAP-Rule MF_01322
PRO_0000067721

Sequences

Sequence LengthMass (Da)Tools
P41185 [UniParc].

Last modified August 30, 2002. Version 2.
Checksum: 1D34A4DFD5971527

FASTA1,413157,681
        10         20         30         40         50         60 
MKDLLKFLKA QTKNEDFDAI KISLASPDMI RSWSFGEVKK PETINYRTFK PERDGLFCAR 

        70         80         90        100        110        120 
IFGPVKDYEC LCGKYKRLKH RGVICEKCGV EVTQSKVRRE RMGHIELSSP TAHIWFLKSL 

       130        140        150        160        170        180 
PSRIGLLLDM PLRDIERVLY FESYVVIETG MTNLEKRQIL TEEQYLDALE EFGDEFYATM 

       190        200        210        220        230        240 
GAEAIQSLLK DINLVKECEN LRIELNETNS ETKRKKLTKR IKLLESFIQS NNKPEWMILT 

       250        260        270        280        290        300 
VLPVLPPDLR PLVPLDGGRF ATSDLNDLYR RVINRNNRLK RLLDLAAPDI IVRNEKRMLQ 

       310        320        330        340        350        360 
EAIDALLDNG RRGRAITGSN KRPLKSLADM IKGKQGRFRQ NLLGKRVDYS GRSVITVGPY 

       370        380        390        400        410        420 
LRLHQCGLPK KMALELFKPF IYGKLEVRGL ATTIKAAKKM VEREEAIVWD ILDEVIREHP 

       430        440        450        460        470        480 
VLLNRAPTLH RLGIQAFEPV LIEGKAIQLH PLVCAAYNAD FDGDQMAVHV PLTLEAQLEA 

       490        500        510        520        530        540 
RALMMSTNNI LSPANGEPII VPSQDVVLGL YYMTREKING KGEGMILNGS NEAEKVYRLE 

       550        560        570        580        590        600 
IAELHSLVKV RITEYKKNKD QSFIPKTKII NTTIGRAILW MIVPKGLPFS IVNQTLGKKD 

       610        620        630        640        650        660 
ISKMLNTCYR ILGLKPTVAF ADQIMYTGFA YAARSGASVG IDDMVIPVKK LNIIHEAEIE 

       670        680        690        700        710        720 
VAEIQEQFQS GLVTAGERYN KVIDIWAAAN ERVAKAMMEN LSTESVFNKK GEKQKQISFN 

       730        740        750        760        770        780 
SIFMMADSGA RGSAAQIRQL AGMRGLMAKP DGSIIETPIT ANFREGLNVL QYFISTHGAR 

       790        800        810        820        830        840 
KGLADTALKT ANSGYLTRRL VDVAQDLVVT QNDCGTHEGI LMTPLIEGGD VKEPLRERVL 

       850        860        870        880        890        900 
GRVTAEKILI PNTENILIER NTLLNEQWCD LLEKNSIDNV KVRSVVNCET DFGVCAYCYG 

       910        920        930        940        950        960 
RDLARGNLVN KGEAIGVIAA QSIGEPGTQL TMRTFHIGGA ASRAATESSI QIKNKGIINL 

       970        980        990       1000       1010       1020 
NNAKSVTNSS GKIVITSRNV ELNIIDNFRR TKETYKVPYG AIMAKGHGEQ VNSGETVAKW 

      1030       1040       1050       1060       1070       1080 
DPHTIPVITE VSGFVRFVDM IDGQSITRQA DELTGLSSIV VLDTAERMTI GKDLRPSLKI 

      1090       1100       1110       1120       1130       1140 
VDRDGNDVLI SGTEMPAQYF LPGKAIVQLD DRVQISSGDT LARVPQESGG TKDITGGLPR 

      1150       1160       1170       1180       1190       1200 
VADLFEARRP KELAILAEIS GIISFGKETK GKRRLIITPV DGSDAYEEMI PKWRQLNVFE 

      1210       1220       1230       1240       1250       1260 
GERVERGDVI SDGPESPHDI LRLRGVQAVT KYIVNEVQEV YRLQGVKIND KHIEVIIRQM 

      1270       1280       1290       1300       1310       1320 
LRKATVIKSG NSEFLDGEQV EFSRIKISNR ILNKQSKIPA TFSRDLLGIT KASLATESFI 

      1330       1340       1350       1360       1370       1380 
SAASFQETTR VLTESAVAGK KDELRGLKEN VIVGRLIPAG TGYAYHKERL NRRHTVNTNQ 

      1390       1400       1410 
IKPNNSSSQI SAEEASASLS ELLNSTLIQH DHT

« Hide

References

« Hide 'large scale' references
[1]"50 million years of genomic stasis in endosymbiotic bacteria."
Tamas I., Klasson L., Canbaeck B., Naeslund A.K., Eriksson A.-S., Wernegreen J.J., Sandstroem J.P., Moran N.A., Andersson S.G.E.
Science 296:2376-2379(2002) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sg.
[2]"Sequence analysis of an aphid endosymbiont DNA fragment containing rpoB (beta-subunit of RNA polymerase) and portions of rplL and rpoC."
Clark M.A., Baumann L., Baumann P.
Curr. Microbiol. 25:283-290(1992) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-209.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE013218 Genomic DNA. Translation: AAM67605.1.
Z11913 Genomic DNA. Translation: CAA77971.1.
PIRS32681.
RefSeqNP_660394.1. NC_004061.1.

3D structure databases

ProteinModelPortalP41185.
SMRP41185. Positions 20-165, 944-1128.
ModBaseSearch...

Protein-protein interaction databases

STRING198804.BUsg034.

Proteomic databases

PRIDEP41185.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAM67605; AAM67605; BUsg_034.
GeneID1005850.
KEGGbas:BUsg034.
PATRIC21246825. VBIBucAph100086_0034.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0086.
KOK03046.
OMADINDKHI.
ProtClustDBPRK00566.

Enzyme and pathway databases

BioCycBAPH198804:GHMG-106-MONOMER.

Family and domain databases

Gene3D2.40.40.20. 2 hits.
HAMAPMF_01322. RNApol_bact_RpoC.
InterProIPR009010. Asp_de-COase-like_dom.
IPR012754. DNA-dir_RpoC_beta_prime.
IPR000722. RNA_pol_asu.
IPR006592. RNA_pol_N.
IPR007080. RNA_pol_Rpb1_1.
IPR007066. RNA_pol_Rpb1_3.
IPR007083. RNA_pol_Rpb1_4.
IPR007081. RNA_pol_Rpb1_5.
[Graphical view]
PfamPF04997. RNA_pol_Rpb1_1. 1 hit.
PF00623. RNA_pol_Rpb1_2. 1 hit.
PF04983. RNA_pol_Rpb1_3. 1 hit.
PF05000. RNA_pol_Rpb1_4. 1 hit.
PF04998. RNA_pol_Rpb1_5. 1 hit.
[Graphical view]
SMARTSM00663. RPOLA_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR02386. rpoC_TIGR. 1 hit.
ProtoNetSearch...

Entry information

Entry nameRPOC_BUCAP
AccessionPrimary (citable) accession number: P41185
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: August 30, 2002
Last modified: May 1, 2013
This is version 85 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

Buchnera aphidicola (subsp. Schizaphis graminum)

Buchnera aphidicola (subsp. Schizaphis graminum): entries and gene names

SIMILARITY comments

Index of protein domains and families

to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·Documents