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P41105

- RL28_MOUSE

UniProt

P41105 - RL28_MOUSE

Protein

60S ribosomal protein L28

Gene

Rpl28

Organism
Mus musculus (Mouse)
Status
Reviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
  1. Functioni

    GO - Molecular functioni

    1. structural constituent of ribosome Source: InterPro

    GO - Biological processi

    1. translation Source: InterPro

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal protein

    Enzyme and pathway databases

    ReactomeiREACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    60S ribosomal protein L28
    Gene namesi
    Name:Rpl28
    OrganismiMus musculus (Mouse)
    Taxonomic identifieri10090 [NCBI]
    Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaSciurognathiMuroideaMuridaeMurinaeMusMus
    ProteomesiUP000000589: Chromosome 7

    Organism-specific databases

    MGIiMGI:101839. Rpl28.

    Subcellular locationi

    GO - Cellular componenti

    1. ribosome Source: UniProtKB-KW

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11Removed1 Publication
    Chaini2 – 13713660S ribosomal protein L28PRO_0000122390Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Modified residuei2 – 21N-acetylserine1 Publication
    Modified residuei115 – 1151PhosphoserineBy similarity

    Keywords - PTMi

    Acetylation, Phosphoprotein

    Proteomic databases

    MaxQBiP41105.
    PaxDbiP41105.
    PRIDEiP41105.

    PTM databases

    PhosphoSiteiP41105.

    Expressioni

    Gene expression databases

    BgeeiP41105.
    CleanExiMM_RPL28.
    GenevestigatoriP41105.

    Interactioni

    Protein-protein interaction databases

    BioGridi202975. 6 interactions.
    DIPiDIP-59974N.
    IntActiP41105. 2 interactions.
    MINTiMINT-1858259.

    Structurei

    3D structure databases

    ProteinModelPortaliP41105.
    SMRiP41105. Positions 1-137.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein L28e family.Curated

    Phylogenomic databases

    eggNOGiNOG148062.
    HOGENOMiHOG000200513.
    HOVERGENiHBG000701.
    InParanoidiP41105.
    KOiK02903.
    OMAiWLIIRNN.
    OrthoDBiEOG74N5JT.
    PhylomeDBiP41105.
    TreeFamiTF300173.

    Family and domain databases

    InterProiIPR029004. L28e/Mak16.
    IPR002672. Ribosomal_L28e.
    [Graphical view]
    PANTHERiPTHR10544. PTHR10544. 1 hit.
    PfamiPF01778. Ribosomal_L28e. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    P41105-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG    50
    VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARATL SSIRHMIRKN 100
    KYRPDLRMAA IRRASAILRS QKPVVVKRKR TRPTKSS 137
    Length:137
    Mass (Da):15,733
    Last modified:January 23, 2007 - v2
    Checksum:i44D9CF515F9B687B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X74856 mRNA. Translation: CAA52848.1.
    AK018714 mRNA. Translation: BAB31362.1.
    AK076133 mRNA. Translation: BAC36209.1.
    BC024395 mRNA. Translation: AAH24395.1.
    CCDSiCCDS39742.1.
    PIRiI48738.
    RefSeqiNP_033107.1. NM_009081.2.
    UniGeneiMm.379002.

    Genome annotation databases

    EnsembliENSMUST00000032597; ENSMUSP00000032597; ENSMUSG00000030432.
    ENSMUST00000078432; ENSMUSP00000104217; ENSMUSG00000030432.
    GeneIDi19943.
    KEGGimmu:19943.
    UCSCiuc009eys.1. mouse.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    X74856 mRNA. Translation: CAA52848.1 .
    AK018714 mRNA. Translation: BAB31362.1 .
    AK076133 mRNA. Translation: BAC36209.1 .
    BC024395 mRNA. Translation: AAH24395.1 .
    CCDSi CCDS39742.1.
    PIRi I48738.
    RefSeqi NP_033107.1. NM_009081.2.
    UniGenei Mm.379002.

    3D structure databases

    ProteinModelPortali P41105.
    SMRi P41105. Positions 1-137.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 202975. 6 interactions.
    DIPi DIP-59974N.
    IntActi P41105. 2 interactions.
    MINTi MINT-1858259.

    PTM databases

    PhosphoSitei P41105.

    Proteomic databases

    MaxQBi P41105.
    PaxDbi P41105.
    PRIDEi P41105.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    Ensembli ENSMUST00000032597 ; ENSMUSP00000032597 ; ENSMUSG00000030432 .
    ENSMUST00000078432 ; ENSMUSP00000104217 ; ENSMUSG00000030432 .
    GeneIDi 19943.
    KEGGi mmu:19943.
    UCSCi uc009eys.1. mouse.

    Organism-specific databases

    CTDi 6158.
    MGIi MGI:101839. Rpl28.

    Phylogenomic databases

    eggNOGi NOG148062.
    HOGENOMi HOG000200513.
    HOVERGENi HBG000701.
    InParanoidi P41105.
    KOi K02903.
    OMAi WLIIRNN.
    OrthoDBi EOG74N5JT.
    PhylomeDBi P41105.
    TreeFami TF300173.

    Enzyme and pathway databases

    Reactomei REACT_196445. SRP-dependent cotranslational protein targeting to membrane.
    REACT_198524. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
    REACT_198528. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

    Miscellaneous databases

    ChiTaRSi RPL28. mouse.
    NextBioi 297461.
    PROi P41105.
    SOURCEi Search...

    Gene expression databases

    Bgeei P41105.
    CleanExi MM_RPL28.
    Genevestigatori P41105.

    Family and domain databases

    InterProi IPR029004. L28e/Mak16.
    IPR002672. Ribosomal_L28e.
    [Graphical view ]
    PANTHERi PTHR10544. PTHR10544. 1 hit.
    Pfami PF01778. Ribosomal_L28e. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence and expression of a cDNA encoding the mouse homologue of the rat ribosomal protein L28."
      Burke P.S., Lium E., Lin C.S., Wolgemuth D.J.
      Gene 142:315-316(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Tissue: Testis.
    2. "The transcriptional landscape of the mammalian genome."
      Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N., Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K., Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.
      , Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R., Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T., Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A., Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B., Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M., Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S., Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E., Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D., Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M., Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H., Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V., Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S., Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H., Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N., Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F., Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G., Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z., Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C., Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y., Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S., Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K., Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R., van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H., Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M., Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C., Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S., Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K., Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M., Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C., Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A., Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.
      Science 309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: C57BL/6J.
      Tissue: Kidney.
    3. "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res. 14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: FVB/N.
      Tissue: Colon.
    4. Bienvenut W.V., Sandilands E., Serrels B., Brunton V.G., Frame M.C.
      Submitted (FEB-2008) to UniProtKB
      Cited for: PROTEIN SEQUENCE OF 2-20 AND 36-46, CLEAVAGE OF INITIATOR METHIONINE, ACETYLATION AT SER-2, IDENTIFICATION BY MASS SPECTROMETRY.
      Tissue: Embryonic fibroblast.

    Entry informationi

    Entry nameiRL28_MOUSE
    AccessioniPrimary (citable) accession number: P41105
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 112 of the entry and version 2 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programChordata Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Direct protein sequencing, Reference proteome

    Documents

    1. MGD cross-references
      Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
    2. Ribosomal proteins
      Ribosomal proteins families and list of entries
    3. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3