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Protein

60S ribosomal protein L28

Gene

Rpl28

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Component of the large ribosomal subunit.By similarity

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionRibonucleoprotein, Ribosomal protein

Enzyme and pathway databases

ReactomeiR-MMU-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-MMU-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-MMU-6791226. Major pathway of rRNA processing in the nucleolus and cytosol.
R-MMU-72689. Formation of a pool of free 40S subunits.
R-MMU-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-MMU-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-MMU-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
60S ribosomal protein L28
Gene namesi
Name:Rpl28
OrganismiMus musculus (Mouse)
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 7

Organism-specific databases

MGIiMGI:101839. Rpl28.

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemoved1 Publication
ChainiPRO_00001223902 – 13760S ribosomal protein L28Add BLAST136

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylserine1 Publication1
Cross-linki58Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Cross-linki65Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)By similarity
Modified residuei115PhosphoserineBy similarity1

Keywords - PTMi

Acetylation, Isopeptide bond, Phosphoprotein, Ubl conjugation

Proteomic databases

EPDiP41105.
PaxDbiP41105.
PeptideAtlasiP41105.
PRIDEiP41105.

PTM databases

iPTMnetiP41105.
PhosphoSitePlusiP41105.

Expressioni

Gene expression databases

BgeeiENSMUSG00000030432.
CleanExiMM_RPL28.
ExpressionAtlasiP41105. baseline and differential.
GenevisibleiP41105. MM.

Interactioni

Subunit structurei

Component of the large ribosomal subunit.By similarity

Protein-protein interaction databases

BioGridi202975. 9 interactors.
DIPiDIP-59974N.
IntActiP41105. 2 interactors.
MINTiMINT-1858259.
STRINGi10090.ENSMUSP00000032597.

Structurei

3D structure databases

ProteinModelPortaliP41105.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG3412. Eukaryota.
ENOG4111T32. LUCA.
GeneTreeiENSGT00390000008732.
HOGENOMiHOG000200513.
HOVERGENiHBG000701.
InParanoidiP41105.
KOiK02903.
OMAiWMIIRNN.
OrthoDBiEOG091G0W22.
PhylomeDBiP41105.
TreeFamiTF300173.

Family and domain databases

InterProiView protein in InterPro
IPR029004. L28e/Mak16.
IPR002672. Ribosomal_L28e.
PANTHERiPTHR10544. PTHR10544. 1 hit.
PfamiView protein in Pfam
PF01778. Ribosomal_L28e. 1 hit.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P41105-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAHLQWMVV RNCSSFLIKR NKQTYSTEPN NLKARNSFRY NGLIHRKTVG
60 70 80 90 100
VEPAADGKGV VVVMKRRSGQ RKPATSYVRT TINKNARATL SSIRHMIRKN
110 120 130
KYRPDLRMAA IRRASAILRS QKPVVVKRKR TRPTKSS
Length:137
Mass (Da):15,733
Last modified:January 23, 2007 - v2
Checksum:i44D9CF515F9B687B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X74856 mRNA. Translation: CAA52848.1.
AK018714 mRNA. Translation: BAB31362.1.
AK076133 mRNA. Translation: BAC36209.1.
BC024395 mRNA. Translation: AAH24395.1.
CCDSiCCDS39742.1.
PIRiI48738.
RefSeqiNP_033107.1. NM_009081.2.
UniGeneiMm.379002.

Genome annotation databases

EnsembliENSMUST00000032597; ENSMUSP00000032597; ENSMUSG00000030432.
ENSMUST00000078432; ENSMUSP00000104217; ENSMUSG00000030432.
GeneIDi19943.
KEGGimmu:19943.
UCSCiuc009eys.1. mouse.

Similar proteinsi

Entry informationi

Entry nameiRL28_MOUSE
AccessioniPrimary (citable) accession number: P41105
Entry historyiIntegrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: August 30, 2017
This is version 141 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families