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Protein

40S ribosomal protein S29-A

Gene

RPS29A

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at protein leveli

Functioni

Cofactori

Zn2+CuratedNote: Binds 1 zinc ion per subunit.Curated

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi21 – 211ZincSequence analysis
Metal bindingi24 – 241ZincSequence analysis
Metal bindingi39 – 391ZincSequence analysis
Metal bindingi42 – 421ZincSequence analysis

GO - Molecular functioni

  • structural constituent of ribosome Source: SGD
  • zinc ion binding Source: GO_Central

GO - Biological processi

  • cytoplasmic translation Source: SGD
Complete GO annotation...

Keywords - Molecular functioni

Ribonucleoprotein, Ribosomal protein

Keywords - Ligandi

Metal-binding, Zinc

Enzyme and pathway databases

BioCyciYEAST:G3O-32454-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Names & Taxonomyi

Protein namesi
Recommended name:
40S ribosomal protein S29-A
Alternative name(s):
S36
YS29
Gene namesi
Name:RPS29A
Synonyms:RPS36A, YS29A
Ordered Locus Names:YLR388W
ORF Names:L8084.11
OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Taxonomic identifieri559292 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
Proteomesi
  • UP000002311 Componenti: Chromosome XII

Organism-specific databases

EuPathDBiFungiDB:YLR388W.
SGDiS000004380. RPS29A.

Subcellular locationi

GO - Cellular componenti

  • cytosolic small ribosomal subunit Source: SGD
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methionineiRemoved2 Publications
Chaini2 – 565540S ribosomal protein S29-APRO_0000131032Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei25 – 251PhosphoserineBy similarity

Keywords - PTMi

Phosphoprotein

Proteomic databases

MaxQBiP41057.
PRIDEiP41057.

PTM databases

iPTMnetiP41057.

Interactioni

Subunit structurei

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains 32 different proteins (encoded by 56 genes) and 1 molecule of RNA (18S). The 60S subunit contains 46 different proteins (encoded by 81 genes) and 3 molecules of RNA (25S, 5.8S and 5S).1 Publication

Protein-protein interaction databases

BioGridi31647. 50 interactions.
DIPiDIP-4643N.
IntActiP41057. 4 interactions.
MINTiMINT-475802.

Structurei

Secondary structure

1
56
Legend: HelixTurnBeta strand
Show more details
Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Beta strandi6 – 83Combined sources
Beta strandi13 – 153Combined sources
Helixi16 – 183Combined sources
Turni22 – 243Combined sources
Beta strandi28 – 314Combined sources
Helixi33 – 353Combined sources
Helixi40 – 5011Combined sources

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10291-56[»]
3J6Yelectron microscopy6.10291-56[»]
3J77electron microscopy6.20291-56[»]
3J78electron microscopy6.30291-56[»]
3V88X-ray3.00d1-56[»]
4U3MX-ray3.00D9/d92-56[»]
4U3NX-ray3.20D9/d92-56[»]
4U3UX-ray2.90D9/d92-56[»]
4U4NX-ray3.10D9/d92-56[»]
4U4OX-ray3.60D9/d92-56[»]
4U4QX-ray3.00D9/d92-56[»]
4U4RX-ray2.80D9/d92-56[»]
4U4UX-ray3.00D9/d92-56[»]
4U4YX-ray3.20D9/d92-56[»]
4U4ZX-ray3.10D9/d92-56[»]
4U50X-ray3.20D9/d92-56[»]
4U51X-ray3.20D9/d92-56[»]
4U52X-ray3.00D9/d92-56[»]
4U53X-ray3.30D9/d92-56[»]
4U55X-ray3.20D9/d92-56[»]
4U56X-ray3.45D9/d92-56[»]
4U6FX-ray3.10D9/d92-56[»]
4V6Ielectron microscopy8.80AN1-56[»]
4V7RX-ray4.00AS/CS1-56[»]
4V88X-ray3.00Ad/Cd1-56[»]
4V8Yelectron microscopy4.30A31-56[»]
4V8Zelectron microscopy6.60A31-56[»]
5DC3X-ray3.25D9/d92-56[»]
5FCIX-ray3.40D9/d92-56[»]
5FCJX-ray3.10D9/d92-56[»]
5I4LX-ray3.10D9/d94-56[»]
ProteinModelPortaliP41057.
SMRiP41057. Positions 4-56.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the ribosomal protein S14P family.Curated

Phylogenomic databases

GeneTreeiENSGT00390000005814.
HOGENOMiHOG000231300.
InParanoidiP41057.
KOiK02980.
OMAiCFREKAA.
OrthoDBiEOG092C5WBL.

Family and domain databases

InterProiIPR001209. Ribosomal_S14.
IPR018271. Ribosomal_S14_CS.
[Graphical view]
PfamiPF00253. Ribosomal_S14. 1 hit.
[Graphical view]
PROSITEiPS00527. RIBOSOMAL_S14. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P41057-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAHENVWFSH PRRYGKGSRQ CRVCSSHTGL IRKYGLNICR QCFREKANDI

GFNKFR
Length:56
Mass (Da):6,661
Last modified:January 23, 2007 - v3
Checksum:iF1A6900EE27748C2
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Sequence conflicti7 – 71W → G AA sequence (PubMed:18782943).Curated
Sequence conflicti14 – 141Y → F in ABM97475 (PubMed:17244705).Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14676 Genomic DNA. Translation: BAA03507.1.
U19729 Genomic DNA. Translation: AAB82350.1.
EF123131 mRNA. Translation: ABM97475.1.
BK006945 Genomic DNA. Translation: DAA09689.1.
PIRiS48503.
RefSeqiNP_013492.3. NM_001182277.3.

Genome annotation databases

EnsemblFungiiYLR388W; YLR388W; YLR388W.
GeneIDi851104.
KEGGisce:YLR388W.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14676 Genomic DNA. Translation: BAA03507.1.
U19729 Genomic DNA. Translation: AAB82350.1.
EF123131 mRNA. Translation: ABM97475.1.
BK006945 Genomic DNA. Translation: DAA09689.1.
PIRiS48503.
RefSeqiNP_013492.3. NM_001182277.3.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3J6Xelectron microscopy6.10291-56[»]
3J6Yelectron microscopy6.10291-56[»]
3J77electron microscopy6.20291-56[»]
3J78electron microscopy6.30291-56[»]
3V88X-ray3.00d1-56[»]
4U3MX-ray3.00D9/d92-56[»]
4U3NX-ray3.20D9/d92-56[»]
4U3UX-ray2.90D9/d92-56[»]
4U4NX-ray3.10D9/d92-56[»]
4U4OX-ray3.60D9/d92-56[»]
4U4QX-ray3.00D9/d92-56[»]
4U4RX-ray2.80D9/d92-56[»]
4U4UX-ray3.00D9/d92-56[»]
4U4YX-ray3.20D9/d92-56[»]
4U4ZX-ray3.10D9/d92-56[»]
4U50X-ray3.20D9/d92-56[»]
4U51X-ray3.20D9/d92-56[»]
4U52X-ray3.00D9/d92-56[»]
4U53X-ray3.30D9/d92-56[»]
4U55X-ray3.20D9/d92-56[»]
4U56X-ray3.45D9/d92-56[»]
4U6FX-ray3.10D9/d92-56[»]
4V6Ielectron microscopy8.80AN1-56[»]
4V7RX-ray4.00AS/CS1-56[»]
4V88X-ray3.00Ad/Cd1-56[»]
4V8Yelectron microscopy4.30A31-56[»]
4V8Zelectron microscopy6.60A31-56[»]
5DC3X-ray3.25D9/d92-56[»]
5FCIX-ray3.40D9/d92-56[»]
5FCJX-ray3.10D9/d92-56[»]
5I4LX-ray3.10D9/d94-56[»]
ProteinModelPortaliP41057.
SMRiP41057. Positions 4-56.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi31647. 50 interactions.
DIPiDIP-4643N.
IntActiP41057. 4 interactions.
MINTiMINT-475802.

PTM databases

iPTMnetiP41057.

Proteomic databases

MaxQBiP41057.
PRIDEiP41057.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiYLR388W; YLR388W; YLR388W.
GeneIDi851104.
KEGGisce:YLR388W.

Organism-specific databases

EuPathDBiFungiDB:YLR388W.
SGDiS000004380. RPS29A.

Phylogenomic databases

GeneTreeiENSGT00390000005814.
HOGENOMiHOG000231300.
InParanoidiP41057.
KOiK02980.
OMAiCFREKAA.
OrthoDBiEOG092C5WBL.

Enzyme and pathway databases

BioCyciYEAST:G3O-32454-MONOMER.
ReactomeiR-SCE-156827. L13a-mediated translational silencing of Ceruloplasmin expression.
R-SCE-1799339. SRP-dependent cotranslational protein targeting to membrane.
R-SCE-72689. Formation of a pool of free 40S subunits.
R-SCE-72695. Formation of the ternary complex, and subsequently, the 43S complex.
R-SCE-72702. Ribosomal scanning and start codon recognition.
R-SCE-72706. GTP hydrolysis and joining of the 60S ribosomal subunit.
R-SCE-975956. Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC).
R-SCE-975957. Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC).

Miscellaneous databases

PROiP41057.

Family and domain databases

InterProiIPR001209. Ribosomal_S14.
IPR018271. Ribosomal_S14_CS.
[Graphical view]
PfamiPF00253. Ribosomal_S14. 1 hit.
[Graphical view]
PROSITEiPS00527. RIBOSOMAL_S14. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiRS29A_YEAST
AccessioniPrimary (citable) accession number: P41057
Secondary accession number(s): A2TBM8, D6VZ23, P05761
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: January 23, 2007
Last modified: September 7, 2016
This is version 131 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Miscellaneous

Present with 6490 molecules/cell in log phase SD medium.1 Publication
There are 2 genes for S29 in yeast.

Keywords - Technical termi

3D-structure, Complete proteome, Direct protein sequencing, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. Ribosomal proteins
    Ribosomal proteins families and list of entries
  3. SIMILARITY comments
    Index of protein domains and families
  4. Yeast
    Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
  5. Yeast chromosome XII
    Yeast (Saccharomyces cerevisiae) chromosome XII: entries and gene names

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.