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Protein

Urease subunit beta

Gene

ureB

Organism
Sporosarcina pasteurii (Bacillus pasteurii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at protein leveli

Functioni

Catalytic activityi

Urea + H2O = CO2 + 2 NH3.UniRule annotation

Pathwayi: urea degradation

This protein is involved in step 1 of the subpathway that synthesizes CO(2) and NH(3) from urea (urease route).UniRule annotation
Proteins known to be involved in this subpathway in this organism are:
  1. Urease subunit gamma (ureA), Urease subunit gamma (ureA), Urease subunit beta (ureB), Urease subunit alpha (ureC), Urease (ureC), Urease subunit beta (ureB), Urease subunit alpha (ureC)
This subpathway is part of the pathway urea degradation, which is itself part of Nitrogen metabolism.
View all proteins of this organism that are known to be involved in the subpathway that synthesizes CO(2) and NH(3) from urea (urease route), the pathway urea degradation and in Nitrogen metabolism.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.

Names & Taxonomyi

Protein namesi
Recommended name:
Urease subunit betaUniRule annotation (EC:3.5.1.5UniRule annotation)
Alternative name(s):
Urea amidohydrolase subunit betaUniRule annotation
Gene namesi
Name:ureBUniRule annotation
OrganismiSporosarcina pasteurii (Bacillus pasteurii)
Taxonomic identifieri1474 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesPlanococcaceaeSporosarcina

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000675691 – 126Urease subunit betaAdd BLAST126

Interactioni

Subunit structurei

Heterotrimer of UreA (gamma), UreB (beta) and UreC (alpha) subunits. Three heterotrimers associate to form the active enzyme.UniRule annotation5 Publications

Chemistry databases

BindingDBiP41021.

Structurei

Secondary structure

1126
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Beta strandi16 – 20Combined sources5
Turni21 – 24Combined sources4
Beta strandi27 – 34Combined sources8
Beta strandi36 – 38Combined sources3
Beta strandi40 – 43Combined sources4
Helixi48 – 50Combined sources3
Beta strandi55 – 57Combined sources3
Helixi59 – 62Combined sources4
Beta strandi65 – 67Combined sources3
Beta strandi74 – 77Combined sources4
Beta strandi82 – 89Combined sources8
Beta strandi104 – 106Combined sources3
Helixi110 – 120Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IE7X-ray1.85B1-126[»]
1S3TX-ray2.10B1-126[»]
1UBPX-ray1.65B5-126[»]
2UBPX-ray2.00B5-126[»]
3UBPX-ray2.00B1-126[»]
4AC7X-ray1.50B1-126[»]
4CEUX-ray1.58B1-126[»]
4CEXX-ray1.59B1-126[»]
4UBPX-ray1.55B1-126[»]
5A6TX-ray1.65B1-126[»]
5FSDX-ray1.75B1-126[»]
5FSEX-ray2.07B1-126[»]
ProteinModelPortaliP41021.
SMRiP41021.
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiP41021.

Family & Domainsi

Sequence similaritiesi

Belongs to the urease beta subunit family.UniRule annotation

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.

Sequencei

Sequence statusi: Complete.

P41021-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNNYIVPG EYRVAEGEIE INAGREKTTI RVSNTGDRPI QVGSHIHFVE
60 70 80 90 100
VNKELLFDRA EGIGRRLNIP SGTAARFEPG EEMEVELTEL GGNREVFGIS
110 120
DLTNGSVDNK ELILQRAKEL GYKGVE
Length:126
Mass (Da):13,959
Last modified:February 1, 1995 - v1
Checksum:iE1BE8E5209586B02
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78411 Genomic DNA. Translation: CAA55174.1.
PIRiS47103.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X78411 Genomic DNA. Translation: CAA55174.1.
PIRiS47103.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1IE7X-ray1.85B1-126[»]
1S3TX-ray2.10B1-126[»]
1UBPX-ray1.65B5-126[»]
2UBPX-ray2.00B5-126[»]
3UBPX-ray2.00B1-126[»]
4AC7X-ray1.50B1-126[»]
4CEUX-ray1.58B1-126[»]
4CEXX-ray1.59B1-126[»]
4UBPX-ray1.55B1-126[»]
5A6TX-ray1.65B1-126[»]
5FSDX-ray1.75B1-126[»]
5FSEX-ray2.07B1-126[»]
ProteinModelPortaliP41021.
SMRiP41021.
ModBaseiSearch...
MobiDBiSearch...

Chemistry databases

BindingDBiP41021.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Enzyme and pathway databases

UniPathwayiUPA00258; UER00370.

Miscellaneous databases

EvolutionaryTraceiP41021.

Family and domain databases

CDDicd00407. Urease_beta. 1 hit.
Gene3Di2.10.150.10. 1 hit.
HAMAPiMF_01954. Urease_beta. 1 hit.
InterProiIPR002019. Urease_beta.
[Graphical view]
PfamiPF00699. Urease_beta. 1 hit.
[Graphical view]
SUPFAMiSSF51278. SSF51278. 1 hit.
TIGRFAMsiTIGR00192. urease_beta. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiURE2_SPOPA
AccessioniPrimary (citable) accession number: P41021
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: November 2, 2016
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  3. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.