Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

P40944

- XYNA_CALSR

UniProt

P40944 - XYNA_CALSR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Endo-1,4-beta-xylanase A

Gene

xynA

Organism
Caldicellulosiruptor sp. (strain Rt8B.4)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

Endohydrolysis of (1->4)-beta-D-xylosidic linkages in xylans.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei490 – 4901Proton donorBy similarity
Active sitei598 – 5981NucleophilePROSITE-ProRule annotation

GO - Molecular functioni

  1. endo-1,4-beta-xylanase activity Source: UniProtKB-EC

GO - Biological processi

  1. xylan catabolic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosidase, Hydrolase

Keywords - Biological processi

Carbohydrate metabolism, Polysaccharide degradation, Xylan degradation

Enzyme and pathway databases

UniPathwayiUPA00114.

Protein family/group databases

CAZyiCBM22. Carbohydrate-Binding Module Family 22.
GH10. Glycoside Hydrolase Family 10.

Names & Taxonomyi

Protein namesi
Recommended name:
Endo-1,4-beta-xylanase A (EC:3.2.1.8)
Short name:
Xylanase A
Alternative name(s):
1,4-beta-D-xylan xylanohydrolase A
Gene namesi
Name:xynA
OrganismiCaldicellulosiruptor sp. (strain Rt8B.4)
Taxonomic identifieri28238 [NCBI]
Taxonomic lineageiBacteriaFirmicutesClostridiaThermoanaerobacteralesThermoanaerobacterales Family III. Incertae SedisCaldicellulosiruptor

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 3434Sequence AnalysisAdd
BLAST
Chaini35 – 684650Endo-1,4-beta-xylanase APRO_0000007981Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliP40944.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini40 – 190151CBM-cenC 1Add
BLAST
Domaini193 – 342150CBM-cenC 2Add
BLAST

Sequence similaritiesi

Keywords - Domaini

Repeat, Signal

Family and domain databases

Gene3Di2.60.120.260. 2 hits.
3.20.20.80. 1 hit.
InterProiIPR003305. CenC_carb-bd.
IPR008979. Galactose-bd-like.
IPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PfamiPF02018. CBM_4_9. 2 hits.
PF00331. Glyco_hydro_10. 1 hit.
[Graphical view]
PRINTSiPR00134. GLHYDRLASE10.
SMARTiSM00633. Glyco_10. 1 hit.
[Graphical view]
SUPFAMiSSF49785. SSF49785. 2 hits.
SSF51445. SSF51445. 1 hit.
PROSITEiPS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

P40944-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MMRSLKSRKL VFILAMLFLI NAIVSLKFIT YSSANQLASK SKYIEYNFEN
60 70 80 90 100
KSVSPLAKYP SNVVLKVTNS TCAEGTFSVL VAGRKNANDG VIVDITKFLD
110 120 130 140 150
FSREYEVSFY VLQTTKKLQR ISVTLEILDS NDKNQVIAAE KVLLPNIWTK
160 170 180 190 200
VSAKVQASNY KKAKRINLIV NMPTSKSDSF YIDLFTIKDL ENAYVLKQEN
210 220 230 240 250
FENKNTGGFL PEDKNCKITL AKDRAYSSAY SLKVQPSQKT KNGKILFPIK
260 270 280 290 300
GLLQKGGTYD FSLLVYQDSS KPVNFSAGIK LNDGKSTKEI VLAKQNVAPK
310 320 330 340 350
KWTQLFATLD LDTRFSAKDV SFFVKPAAAI SYYLDLYSIS DENWGQPVPD
360 370 380 390 400
YNLPSLCEKY KNYFKIGVAV PYRALTNPVD VEVIKRHFNS ITPENEMKPE
410 420 430 440 450
SLQPYEGGFS FSIADEYVDF CKKDNISLRG HTLVWHQQTP SWFFTNPETG
460 470 480 490 500
EKLTNSEKDK EILLDRLKKH IQTVVGRYKG KVYAWDVVNE AIDENQPDGY
510 520 530 540 550
RRSDWYNILG PEYIEKAFIW AHEADPKAKL FYNDYSTEDP YKREFIYKLI
560 570 580 590 600
KNLKAKGVPV HGVGLQCHIS LDWPDVSEIE ETVKLFSRIP GLEIHFTEID
610 620 630 640 650
ISIAKNMTDD DAYNRYLLVQ QAQKLKAIFD VLKKYRNVVT SVTFWGLKDD
660 670 680
YSWLRGDMPL LSDKDYQPKF AFWSLIDPSV VPKE
Length:684
Mass (Da):78,354
Last modified:February 1, 1995 - v1
Checksum:i0AE575F4FB4BA5E6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L18965 Genomic DNA. Translation: AAB42044.1.
PIRiS41788.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
L18965 Genomic DNA. Translation: AAB42044.1 .
PIRi S41788.

3D structure databases

ProteinModelPortali P40944.
ModBasei Search...
MobiDBi Search...

Protein family/group databases

CAZyi CBM22. Carbohydrate-Binding Module Family 22.
GH10. Glycoside Hydrolase Family 10.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Enzyme and pathway databases

UniPathwayi UPA00114 .

Family and domain databases

Gene3Di 2.60.120.260. 2 hits.
3.20.20.80. 1 hit.
InterProi IPR003305. CenC_carb-bd.
IPR008979. Galactose-bd-like.
IPR001000. Glyco_hydro_10.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view ]
Pfami PF02018. CBM_4_9. 2 hits.
PF00331. Glyco_hydro_10. 1 hit.
[Graphical view ]
PRINTSi PR00134. GLHYDRLASE10.
SMARTi SM00633. Glyco_10. 1 hit.
[Graphical view ]
SUPFAMi SSF49785. SSF49785. 2 hits.
SSF51445. SSF51445. 1 hit.
PROSITEi PS00591. GLYCOSYL_HYDROL_F10. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Cloning, sequencing and overexpression in Escherichia coli of a xylanase gene, xynA from the thermophilic bacterium Rt8B.4 genus Caldicellulosiruptor."
    Dwivedi P.P., Gibbs M.D., Saul D.J., Bergquist P.L.
    Appl. Microbiol. Biotechnol. 45:86-93(1996) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiXYNA_CALSR
AccessioniPrimary (citable) accession number: P40944
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: October 1, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3