Reviewed, UniProtKB/Swiss-Prot P40921 (EF1G_SCHPO)

Names and origin

Protein names

Recommended name:
    Elongation factor 1-gamma
      Short name=EF-1-gamma
Alternative name(s):
    eEF-1B gamma

Gene names

Name:	tef3
ORF Names:	SPAC29A4.02c

Organism

Schizosaccharomyces pombe (Fission yeast) [Complete proteome]

Taxonomic identifier

4896 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Taphrinomycotina › Schizosaccharomycetes › Schizosaccharomycetales › Schizosaccharomycetaceae › Schizosaccharomyces

Protein attributes

Sequence length	409 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Function	Probably plays a role in anchoring the complex to other cellular components.
Subunit structure	EF-1 is composed of four subunits: alpha, beta, delta, and gamma.
Sequence similarities	Contains 1 EF-1-gamma C-terminal domain. Contains 1 GST C-terminal domain. Contains 1 GST N-terminal domain.

Ontologies

Keywords
Biological process	Protein biosynthesis
Molecular function	Elongation factor
Technical term	Complete proteome Direct protein sequencing
Gene Ontology (GO)
Biological process	translational elongation Inferred from electronic annotation. Source: InterPro
Cellular component	cytosol Inferred from direct assay. Source: GeneDB_SPombe eukaryotic translation elongation factor 1 complex Inferred from electronic annotation. Source: InterPro
Molecular function	translation elongation factor activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 409	409	Elongation factor 1-gamma		PRO_0000208830
Regions
	Domain	2 – 81	80	GST N-terminal
	Domain	86 – 212	127	GST C-terminal
	Domain	251 – 409	159	EF-1-gamma C-terminal
Experimental info
	Sequence conflict	246	1	R → A in CAB10129. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P40921-1 [UniParc]. Last modified February 1, 1995. Version 1. Checksum: A49CB947A9F66DF0	FASTA	409	45,786
	10 20 30 40 50 60 MSVGTVYGKI GSPRVLFCVS VAAVAGVEVE HVDVQPHNFP ADLAAKFPLQ KMPVFVGKDG 70 80 90 100 110 120 FPLSETLAIA FYLASLNKTR ALNGTTAEEK AKVLQYCSFT NSELPGAFRP IIAPRVFGAP 130 140 150 160 170 180 YDEQAAKEAE TAIALIFARF DEELASKTYL VGSRLTLADI FFTCFLKFGA TYVLTKSYLA 190 200 210 220 230 240 KYTHIYRYYQ TIYHQAKLDA ITEPLKFIDQ PLPIIKAENK EAAPAKKAEK KKDEKKKNAP 250 260 270 280 290 300 KPQAERPAKP PKHPLASAPN GSFDIEEYKR VYSNQDTRSG ALPWFFEHFD PENYSVWKVD 310 320 330 340 350 360 YSYPEDLKQP VFMTNNLIGG FFQRLEASRK YIFGCCVVIG ENGDNTITGA FVIKGHDYVP 370 380 390 400 AFDVAPDWGS YTFTKLDINK PEDKAFIEDA WAWDKPIEGR EVADGKVCK

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence of a fission yeast gene encoding a protein with extensive homology to eukaryotic elongation factor-1 gamma." Momoi H., Yamada H., Ueguchi C., Mizuno T. Gene 134:119-122(1993) [PubMed: 8244022] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], PROTEIN SEQUENCE OF 226-244. Strain: ATCC 38366 / 972.
[2]	"The genome sequence of Schizosaccharomyces pombe." Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A., Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S., Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M. , Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S., Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S., Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D., Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P., Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K., O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M., Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N., Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A., Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R., Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A., Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A., Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H., Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S., Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C., Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A., Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M., del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S., Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R., Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G., Nurse P. Nature 415:871-880(2002) [PubMed: 11859360] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 38366 / 972.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D14606 Genomic DNA. Translation: BAA03456.1. CU329670 Genomic DNA. Translation: CAB10129.1.
PIR	JT0764. T38487.
RefSeq	NP_594880.1.
3D structure databases
HSSP	HSSP built from PDB template 1PBU based on UniProtKB P26641.
ModBase	Search...
Genome annotation databases
GeneID	2542298.
KEGG	spo:SPAC29A4.02c.
Organism-specific databases
GeneDB_Spombe	SPAC29A4.02c.
Gene expression databases
ArrayExpress	P40921.
Family and domain databases
InterPro	IPR010987. Glutathione-S-Trfase_C-like. IPR004045. Glutathione_S-Trfase_N. IPR017933. Glutathione_S_Trfase/Cl_chnl_C. IPR004046. GST_C. IPR012335. Thioredoxin_fold. IPR001662. Transl_elong_EF1_G_con. [Graphical view]
Gene3D	G3DSA:1.20.1050.10. GST_C_like. 1 hit. G3DSA:3.40.30.10. Thioredoxin_fold. 1 hit. G3DSA:3.30.70.1010. Transl_elong_EF1_G_con. 1 hit.
Pfam	PF00647. EF1G. 1 hit. PF00043. GST_C. 1 hit. PF02798. GST_N. 1 hit. [Graphical view]
ProDom	PD006217. EF1_G. 1 hit. [Graphical view] [Entries sharing at least one domain]
PROSITE	PS50040. EF1G_C. 1 hit. PS50405. GST_CTER. 1 hit. PS50404. GST_NTER. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

EF1G_SCHPO

Accession

Primary (citable) accession number: P40921
Secondary accession number(s): O14005

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	June 16, 2009
This is version 65 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)