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Reviewed, UniProtKB/Swiss-Prot P40912 (INV1_HANAN)

Last modified July 7, 2009. Version 45. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Invertase
    EC=3.2.1.26
Alternative name(s):
    Beta-fructofuranosidase 2
    Saccharase
Gene names
Name: INV1
OrganismHansenula anomala (Yeast) (Candida pelliculosa)
Taxonomic identifier4927 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Wickerhamomycetaceae › Wickerhamomyces

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Protein attributes

Sequence length550 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Hydrolysis of terminal non-reducing beta-D-fructofuranoside residues in beta-D-fructofuranosides.

Sequence similarities

Belongs to the glycosyl hydrolase 32 family.

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Ontologies

Keywords
   DomainSignal
   Molecular functionGlycosidase
Hydrolase
   PTMGlycoprotein
Gene Ontology (GO)
   Biological processcarbohydrate metabolic process

Inferred from electronic annotation. Source: InterPro

   Molecular functionbeta-fructofuranosidase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2222 Potential
Chain23 – 550528Invertase
PRO_0000033395

Regions

Region39 – 424Substrate binding By similarity
Region103 – 1042Substrate binding By similarity
Region170 – 1712Substrate binding By similarity

Sites

Active site421 By similarity
Binding site601Substrate By similarity
Binding site2231Substrate By similarity
Binding site3131Substrate By similarity

Amino acid modifications

Glycosylation1121N-linked (GlcNAc...) Potential
Glycosylation1131N-linked (GlcNAc...) Potential
Glycosylation1191N-linked (GlcNAc...) Potential
Glycosylation1651N-linked (GlcNAc...) Potential
Glycosylation2111N-linked (GlcNAc...) Potential
Glycosylation2371N-linked (GlcNAc...) Potential
Glycosylation3331N-linked (GlcNAc...) Potential
Glycosylation3641N-linked (GlcNAc...) Potential
Glycosylation3981N-linked (GlcNAc...) Potential
Glycosylation4201N-linked (GlcNAc...) Potential

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Sequences

Sequence LengthMass (Da)Tools
P40912-1 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 192BCD722455E121

FASTA55063,188
        10         20         30         40         50         60 
MIQLSPLLLL PLFSVFNSIA DASTEYLRPQ IHLTPDQGWM NDPNGMFYDR KDKLWHVYFQ 

        70         80         90        100        110        120 
HNPDKKSIWA TPVTWGHSTS KDLLTWDYHG NALEPENDDE GIFSGSVVVD RNNTSGFFND 

       130        140        150        160        170        180 
STDPEQRIVA IYTNNAQLQT QEIAYSLDKG YSFIKYDQNP VINVNSSQQR DPKVLWHDES 

       190        200        210        220        230        240 
NQWIMVVAKT QEFKVQIYGS PDLKKWDLKS NFTSNGYLGF QYECPGLFKL PIENPLNDTV 

       250        260        270        280        290        300 
TSKWVLLLAI NPGSPLGGSI NEYFIGDFDG TTFHPDDGAT RFMDIGKDFY AFQSFDNTEP 

       310        320        330        340        350        360 
EDGALGLAWA SNWQYANTVP TENWRSSMSL VRNYTLKYVD VNPENYGLTL IQKPVYDTKE 

       370        380        390        400        410        420 
TRLNETLKTL ETINEYEVND LKLDKSSFVA TDFNTERNAT GVFEFDLKFT QTDLKMGYSN 

       430        440        450        460        470        480 
MTTQFGLYIH SQTVKGSQET LQLVFDTLST TWYIDRTTQH SFQRNSPVFT ERISTYVEKI 

       490        500        510        520        530        540 
DTTDQGNVYT LYGVVDRNIL ELYFNDGSIA MTNTFFFREG KIPTSFEVVC DSEKSFITID 

       550 
ELSVRELARK

« Hide

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References

[1]"Cloning and sequence analysis of the invertase gene INV 1 from the yeast Pichia anomala."
Perez J.A., Rodriguez J., Rodriguez L., Ruiz T.
Curr. Genet. 29:234-240(1996) [PubMed: 8595669] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

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Cross-references

Sequence databases

X80640 Genomic DNA. Translation: CAA56684.1.
PIRS65753.

3D structure databases

ModBaseSearch...

Protein family/group databases

CAZyGH32. Glycoside Hydrolase Family 32.

Enzyme and pathway databases

BRENDA3.2.1.26. 3702.

Family and domain databases

InterProIPR001362. Glyco_hydro_32.
IPR018053. Glyco_hydro_32_AS.
IPR013189. Glyco_hydro_32_C.
IPR013148. Glyco_hydro_32_N.
[Graphical view]
PfamPF08244. Glyco_hydro_32C. 1 hit.
PF00251. Glyco_hydro_32N. 1 hit.
[Graphical view]
SMARTSM00640. Glyco_32. 1 hit.
[Graphical view]
PROSITEPS00609. GLYCOSYL_HYDROL_F32. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameINV1_HANAN
AccessionPrimary (citable) accession number: P40912
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: July 7, 2009
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents