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Protein

Sexual differentiation process protein isp4

Gene

isp4

Organism
Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

  • tetrapeptide transmembrane transporter activity Source: PomBase

GO - Biological processi

  • protein transport Source: UniProtKB-KW
  • tetrapeptide transmembrane transport Source: PomBase
Complete GO annotation...

Keywords - Biological processi

Peptide transport, Protein transport, Transport

Protein family/group databases

TCDBi2.A.67.1.2. the oligopeptide transporter (opt) family.

Names & Taxonomyi

Protein namesi
Recommended name:
Sexual differentiation process protein isp4
Gene namesi
Name:isp4
ORF Names:SPBC29B5.02c
OrganismiSchizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
Taxonomic identifieri284812 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaTaphrinomycotinaSchizosaccharomycetesSchizosaccharomycetalesSchizosaccharomycetaceaeSchizosaccharomyces
Proteomesi
  • UP000002485 Componenti: Chromosome II

Organism-specific databases

EuPathDBiFungiDB:SPBC29B5.02c.
PomBaseiSPBC29B5.02c. isp4.

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei94 – 114HelicalSequence analysisAdd BLAST21
Transmembranei121 – 141HelicalSequence analysisAdd BLAST21
Transmembranei167 – 187HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei264 – 284HelicalSequence analysisAdd BLAST21
Transmembranei339 – 359HelicalSequence analysisAdd BLAST21
Transmembranei413 – 433HelicalSequence analysisAdd BLAST21
Transmembranei461 – 481HelicalSequence analysisAdd BLAST21
Transmembranei490 – 510HelicalSequence analysisAdd BLAST21
Transmembranei512 – 532HelicalSequence analysisAdd BLAST21
Transmembranei537 – 557HelicalSequence analysisAdd BLAST21
Transmembranei572 – 592HelicalSequence analysisAdd BLAST21
Transmembranei611 – 631HelicalSequence analysisAdd BLAST21
Transmembranei642 – 662HelicalSequence analysisAdd BLAST21
Transmembranei683 – 703HelicalSequence analysisAdd BLAST21
Transmembranei732 – 752HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

  • endoplasmic reticulum Source: PomBase
  • endoplasmic reticulum membrane Source: UniProtKB-SubCell
  • Golgi apparatus Source: PomBase
  • integral component of plasma membrane Source: GO_Central
  • plasma membrane Source: PomBase
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002137871 – 785Sexual differentiation process protein isp4Add BLAST785

Proteomic databases

MaxQBiP40900.
PRIDEiP40900.

Expressioni

Developmental stagei

Transcribed specifically during sexual development.

Interactioni

Protein-protein interaction databases

BioGridi276893. 9 interactors.
MINTiMINT-4689816.

Structurei

3D structure databases

ProteinModelPortaliP40900.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

HOGENOMiHOG000166970.
InParanoidiP40900.
OMAiISSHVFM.
OrthoDBiEOG092C0W76.
PhylomeDBiP40900.

Family and domain databases

InterProiIPR004648. Oligpept_transpt.
IPR004813. OPT.
[Graphical view]
PfamiPF03169. OPT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00727. ISP4_OPT. 1 hit.
TIGR00728. OPT_sfam. 1 hit.

Sequencei

Sequence statusi: Complete.

P40900-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIGSINESPI EEHMNDSPST KEKADSVDIS DYIVSHSDDS LSKDIKKDTK
60 70 80 90 100
SFLDVEHGEI STVDEFEEDS PYPEVRAAVP PTDDPSMPCN TIRMWTIGLI
110 120 130 140 150
YSTVGAAVNM FFSLRNPTVT LSVLISELLA YPALQIWDLI FPDREFRIGR
160 170 180 190 200
LKFNFKPGPF NVKEHALIVV MSSVSFGNAY STDIILAQRV HYKQRFGFGY
210 220 230 240 250
EICLTLATQL IGYGLAGLSR RLLVRPASML WPVNLVQCTL IKTLHRKDLR
260 270 280 290 300
NAVANGWRIS PFRFFLYVFI ASFIWNWFPS YIFQALSLFA WVTWIRPNSP
310 320 330 340 350
TVNQIFGEST GISILPMTFD WNQISAYILS PLMAPADALM NILLGVILFF
360 370 380 390 400
WIVTPALNFT NTWYGDYLPI SSSGIIDHFG NSYNVTRILT KDATFDLDAY
410 420 430 440 450
QNYSPIFMST TYALAFGLSF ASITSVIFHV ILYHGKEIYD RLRDPPAPDI
460 470 480 490 500
HEKLMKAYDE VPFYWYLSVF LAFFGMMMGT IYGWKTETPW WVIIVGVIFS
510 520 530 540 550
AVWFIPIGIV QAITNIQLGL NVFTEFIVGY MYPGRPLAMM IFKTVGYITM
560 570 580 590 600
TQGLAFAADL KFGHYMKLPP RIMFYTQMIA TIWSCFVQIG VLDWALGNID
610 620 630 640 650
NVCQADQPDN YTCPNATVFF NSSVIWGVIG PKRMFSGKNT YTGLQYFWLA
660 670 680 690 700
GVLGTILFWA LWKKWPQKWW GQLNGPLIFG GTGYIPPATP VNYLAWSGIG
710 720 730 740 750
LFFNYYLKKI FADWWQKYNF TLSAALDTGT QLSVIILFFC LQLPMVNFPD
760 770 780
WWGNDGAFNT LDATGAAVRK LVNESAGEFF GPAEW
Length:785
Mass (Da):89,192
Last modified:August 14, 2001 - v2
Checksum:i3F19825269BFA75D
GO

Sequence cautioni

The sequence BAA12193 differs from that shown. Sequencing errors.Curated
The sequence BAA12193 differs from that shown. Reason: Frameshift at several positions.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti725Missing in BAA03147 (PubMed:7954893).Curated1
Sequence conflicti777 – 785GEFFGPAEW → R in BAA03147 (PubMed:7954893).Curated9

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14061 mRNA. Translation: BAA03147.1.
D83992 Genomic DNA. Translation: BAA12193.1. Frameshift.
CU329671 Genomic DNA. Translation: CAC05511.1.
AB027895 Genomic DNA. Translation: BAA87199.1.
PIRiS45495.
RefSeqiNP_595653.1. NM_001021547.2.

Genome annotation databases

EnsemblFungiiSPBC29B5.02c.1; SPBC29B5.02c.1:pep; SPBC29B5.02c.
GeneIDi2540364.
KEGGispo:SPBC29B5.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
D14061 mRNA. Translation: BAA03147.1.
D83992 Genomic DNA. Translation: BAA12193.1. Frameshift.
CU329671 Genomic DNA. Translation: CAC05511.1.
AB027895 Genomic DNA. Translation: BAA87199.1.
PIRiS45495.
RefSeqiNP_595653.1. NM_001021547.2.

3D structure databases

ProteinModelPortaliP40900.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi276893. 9 interactors.
MINTiMINT-4689816.

Protein family/group databases

TCDBi2.A.67.1.2. the oligopeptide transporter (opt) family.

Proteomic databases

MaxQBiP40900.
PRIDEiP40900.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiSPBC29B5.02c.1; SPBC29B5.02c.1:pep; SPBC29B5.02c.
GeneIDi2540364.
KEGGispo:SPBC29B5.02c.

Organism-specific databases

EuPathDBiFungiDB:SPBC29B5.02c.
PomBaseiSPBC29B5.02c. isp4.

Phylogenomic databases

HOGENOMiHOG000166970.
InParanoidiP40900.
OMAiISSHVFM.
OrthoDBiEOG092C0W76.
PhylomeDBiP40900.

Miscellaneous databases

PROiP40900.

Family and domain databases

InterProiIPR004648. Oligpept_transpt.
IPR004813. OPT.
[Graphical view]
PfamiPF03169. OPT. 1 hit.
[Graphical view]
TIGRFAMsiTIGR00727. ISP4_OPT. 1 hit.
TIGR00728. OPT_sfam. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiISP4_SCHPO
AccessioniPrimary (citable) accession number: P40900
Secondary accession number(s): P78943, Q9HGP2, Q9UU01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: August 14, 2001
Last modified: October 5, 2016
This is version 108 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Schizosaccharomyces pombe
    Schizosaccharomyces pombe: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.