Reviewed,
UniProtKB/Swiss-Prot P40886 (HXT8_YEAST)
Last modified
October 13, 2009.
Version 70.
History...
Clusters with 100%,
90%,
50% identity |
Documents (3) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Hexose transporter HXT8 | ||||||
| Gene names |
| ||||||
| Organism | Saccharomyces cerevisiae (Baker's yeast) [Complete proteome] | ||||||
| Taxonomic identifier | 4932 [NCBI] | ||||||
| Taxonomic lineage | Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces |
Protein attributes
| Sequence length | 569 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Evidence at protein level. |
General annotation (Comments)
| Function | Probable glucose transporter. |
| Subcellular location | |
| Miscellaneous | Present with 623 molecules/cell in log phase SD medium. Ref.3 |
| Sequence similarities | Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification] |
Ontologies
| Keywords | |
|---|---|
| Biological process | Sugar transport Transport |
| Cellular component | Membrane |
| Domain | Repeat Transmembrane |
| PTM | Glycoprotein |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | hexose transport Inferred from genetic interaction. Source: SGD transmembrane transportInferred from electronic annotation. Source: InterPro |
| Cellular component | integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | fructose transmembrane transporter activity Inferred from genetic interaction. Source: SGD glucose transmembrane transporter activityInferred from genetic interaction. Source: SGD mannose transmembrane transporter activityInferred from genetic interaction. Source: SGD |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 569 | 569 | Hexose transporter HXT8 | PRO_0000050398 | |||||
Regions | |||||||||
| Topological domain | 1 – 61 | 61 | Cytoplasmic Potential | ||||||
| Transmembrane | 62 – 82 | 21 | 1 Potential | ||||||
| Topological domain | 83 – 118 | 36 | Extracellular Potential | ||||||
| Transmembrane | 119 – 139 | 21 | 2 Potential | ||||||
| Topological domain | 140 – 145 | 6 | Cytoplasmic Potential | ||||||
| Transmembrane | 146 – 166 | 21 | 3 Potential | ||||||
| Topological domain | 167 – 176 | 10 | Extracellular Potential | ||||||
| Transmembrane | 177 – 197 | 21 | 4 Potential | ||||||
| Topological domain | 198 – 203 | 6 | Cytoplasmic Potential | ||||||
| Transmembrane | 204 – 224 | 21 | 5 Potential | ||||||
| Topological domain | 225 – 238 | 14 | Extracellular Potential | ||||||
| Transmembrane | 239 – 259 | 21 | 6 Potential | ||||||
| Topological domain | 260 – 342 | 83 | Cytoplasmic Potential | ||||||
| Transmembrane | 343 – 359 | 17 | 7 Potential | ||||||
| Topological domain | 360 – 365 | 6 | Extracellular Potential | ||||||
| Transmembrane | 366 – 383 | 18 | 8 Potential | ||||||
| Topological domain | 384 – 390 | 7 | Cytoplasmic Potential | ||||||
| Transmembrane | 391 – 411 | 21 | 9 Potential | ||||||
| Topological domain | 412 – 433 | 22 | Extracellular Potential | ||||||
| Transmembrane | 434 – 454 | 21 | 10 Potential | ||||||
| Topological domain | 455 – 471 | 17 | Cytoplasmic Potential | ||||||
| Transmembrane | 472 – 492 | 21 | 11 Potential | ||||||
| Topological domain | 493 | 1 | Extracellular Potential | ||||||
| Transmembrane | 494 – 514 | 21 | 12 Potential | ||||||
| Topological domain | 515 – 569 | 55 | Cytoplasmic Potential | ||||||
Amino acid modifications | |||||||||
| Glycosylation | 92 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 102 | 1 | N-linked (GlcNAc...) Potential | ||||||
| Glycosylation | 429 | 1 | N-linked (GlcNAc...) Potential | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| Z34098 Genomic DNA. Translation: CAA83997.1. Z49489 Genomic DNA. Translation: CAA89511.1. | |
| PIR | S50771. |
| RefSeq | NP_012321.1. |
3D structure databases | |
| ModBase | Search... |
Protein-protein interaction databases | |
| DIP | DIP:8121N. |
| STRING | P40886. |
Proteomic databases | |
| PeptideAtlas | P40886. |
Genome annotation databases | |
| Ensembl | YJL214W; YJL214W; YJL214W; Saccharomyces cerevisiae. [Genome view] |
| GeneID | 853216. |
| GenomeReviews | Gene locus YJL214W in contig Y13136_GR. |
| KEGG | sce:YJL214W. |
| NMPDR | fig|4932.3.peg.3284. |
Organism-specific databases | |
| CYGD | YJL214w. |
| SGD | S000003750. HXT8. |
Phylogenomic databases | |
| HOGENOM | P40886. |
Gene expression databases | |
| ArrayExpress | P40886. |
| Genevestigator | P40886. |
| GermOnline | YJL214W. Saccharomyces cerevisiae. |
Family and domain databases | |
| InterPro | IPR005828. Sub_transporter. IPR003663. Sugar/inositol_transpt. IPR005829. Sugar_transporter_CS. [Graphical view] |
| Pfam | PF00083. Sugar_tr. 1 hit. [Graphical view] |
| PRINTS | PR00171. SUGRTRNSPORT. |
| TIGRFAMs | TIGR00879. SP. 1 hit. |
| PROSITE | PS50850. MFS. 1 hit. PS00216. SUGAR_TRANSPORT_1. 1 hit. PS00217. SUGAR_TRANSPORT_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Other Resources | |
| NextBio | 973407. |
Entry information
| Entry name | HXT8_YEAST | ||||||||
| Accession | Primary (citable) accession number: P40886 | ||||||||
| Entry history |
| ||||||||
| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | FPAP (Fungal Proteome Annotation Project) | ||||||||
Relevant documents
| SIMILARITY comments Index of protein domains and families |
| Yeast Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD |
| Yeast chromosome X Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names |

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