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P40885

- HXT9_YEAST

UniProt

P40885 - HXT9_YEAST

Protein

Hexose transporter HXT9

Gene

HXT9

Organism
Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 110 (01 Oct 2014)
      Sequence version 1 (01 Feb 1995)
      Previous versions | rss
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    Functioni

    Probable glucose transporter.

    GO - Molecular functioni

    1. fructose transmembrane transporter activity Source: SGD
    2. galactose transmembrane transporter activity Source: SGD
    3. glucose transmembrane transporter activity Source: SGD
    4. mannose transmembrane transporter activity Source: SGD

    GO - Biological processi

    1. fructose transport Source: GOC
    2. galactose transport Source: GOC
    3. glucose transport Source: GOC
    4. hexose transport Source: SGD
    5. mannose transport Source: GOC

    Keywords - Biological processi

    Sugar transport, Transport

    Enzyme and pathway databases

    BioCyciYEAST:G3O-31643-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Hexose transporter HXT9
    Gene namesi
    Name:HXT9
    Ordered Locus Names:YJL219W
    ORF Names:HRC567, J0222
    OrganismiSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
    Taxonomic identifieri559292 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces
    ProteomesiUP000002311: Chromosome X

    Organism-specific databases

    CYGDiYJL219w.
    SGDiS000003755. HXT9.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. plasma membrane Source: SGD

    Keywords - Cellular componenti

    Membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 567567Hexose transporter HXT9PRO_0000050399Add
    BLAST

    Amino acid modifications

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Glycosylationi87 – 871N-linked (GlcNAc...)Sequence Analysis
    Glycosylationi227 – 2271N-linked (GlcNAc...)Sequence Analysis

    Keywords - PTMi

    Glycoprotein

    Expressioni

    Gene expression databases

    GenevestigatoriP40885.

    Interactioni

    Protein-protein interaction databases

    BioGridi33562. 26 interactions.
    DIPiDIP-4609N.
    IntActiP40885. 1 interaction.
    MINTiMINT-479522.
    STRINGi4932.YJL219W.

    Structurei

    3D structure databases

    ProteinModelPortaliP40885.
    SMRiP40885. Positions 64-526.
    ModBaseiSearch...
    MobiDBiSearch...

    Topological domain

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Topological domaini1 – 5656CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini78 – 11235ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini134 – 1396CytoplasmicSequence Analysis
    Topological domaini161 – 17010ExtracellularSequence Analysis
    Topological domaini192 – 1976CytoplasmicSequence Analysis
    Topological domaini219 – 23214ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini254 – 33683CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini354 – 3596ExtracellularSequence Analysis
    Topological domaini378 – 3847CytoplasmicSequence Analysis
    Topological domaini406 – 42924ExtracellularSequence AnalysisAdd
    BLAST
    Topological domaini451 – 46717CytoplasmicSequence AnalysisAdd
    BLAST
    Topological domaini489 – 4891ExtracellularSequence Analysis
    Topological domaini511 – 56757CytoplasmicSequence AnalysisAdd
    BLAST

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei57 – 7721Helical; Name=1Sequence AnalysisAdd
    BLAST
    Transmembranei113 – 13321Helical; Name=2Sequence AnalysisAdd
    BLAST
    Transmembranei140 – 16021Helical; Name=3Sequence AnalysisAdd
    BLAST
    Transmembranei171 – 19121Helical; Name=4Sequence AnalysisAdd
    BLAST
    Transmembranei198 – 21821Helical; Name=5Sequence AnalysisAdd
    BLAST
    Transmembranei233 – 25321Helical; Name=6Sequence AnalysisAdd
    BLAST
    Transmembranei337 – 35317Helical; Name=7Sequence AnalysisAdd
    BLAST
    Transmembranei360 – 37718Helical; Name=8Sequence AnalysisAdd
    BLAST
    Transmembranei385 – 40521Helical; Name=9Sequence AnalysisAdd
    BLAST
    Transmembranei430 – 45021Helical; Name=10Sequence AnalysisAdd
    BLAST
    Transmembranei468 – 48821Helical; Name=11Sequence AnalysisAdd
    BLAST
    Transmembranei490 – 51021Helical; Name=12Sequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Repeat, Transmembrane, Transmembrane helix

    Phylogenomic databases

    GeneTreeiENSGT00720000108754.
    HOGENOMiHOG000202870.
    KOiK08139.
    OMAiLRIVISM.
    OrthoDBiEOG73JM4H.

    Family and domain databases

    InterProiIPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view]
    PfamiPF00083. Sugar_tr. 1 hit.
    [Graphical view]
    PRINTSiPR00171. SUGRTRNSPORT.
    SUPFAMiSSF103473. SSF103473. 1 hit.
    TIGRFAMsiTIGR00879. SP. 1 hit.
    PROSITEiPS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    P40885-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSGVNNTSAN DLSTTESNSN SVANAPSVKT EHNDSKNSLN LDATEPPIDL    50
    PQKPLSAYTT VAILCLMIAF GGFIFGWDTG TISGFVNLSD FIRRFGQKND 100
    KGTYYLSKVR MGLIVSIFNI GCAIGGIVLS KVGDIYGRRI GLITVTAIYV 150
    VGILIQITSI NKWYQYFIGR IISGLGVGGI AVLSPMLISE VAPKQIRGTL 200
    VQLYQLMCTM GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA WTTFMVSGMM 250
    FVPESPRYLI EVGKDEEAKR SLSKSNKVSV DDPALLAEYD TIKAGIELEK 300
    LAGNASWSEL LSTKTKVFQR VLMGVMIQSL QQLTGDNYFF YYGTTIFKSV 350
    GLKDSFQTSI IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF 400
    ASVGVTKLWP QGSSHQDITS QGAGNCMIVF TMFFIFSFAT TWAGGCYVIV 450
    SETFPLRVKS RGMAIATAAN WMWGFLISFF TPFITGAINF YYGYVFLGCL 500
    VFAYFYVFFF VPETKGLTLE EVNTMWLEGV PAWKSASWVP PERRTADYDA 550
    DAIDHDDRPI YKRFFSS 567
    Length:567
    Mass (Da):62,858
    Last modified:February 1, 1995 - v1
    Checksum:i2CF4C8617D9B2701
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z34098 Genomic DNA. Translation: CAA83991.1.
    Z49494 Genomic DNA. Translation: CAA89516.1.
    BK006943 Genomic DNA. Translation: DAA08593.1.
    PIRiS50708.
    RefSeqiNP_012316.1. NM_001181652.1.

    Genome annotation databases

    EnsemblFungiiYJL219W; YJL219W; YJL219W.
    GeneIDi853236.
    KEGGisce:YJL219W.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    Z34098 Genomic DNA. Translation: CAA83991.1 .
    Z49494 Genomic DNA. Translation: CAA89516.1 .
    BK006943 Genomic DNA. Translation: DAA08593.1 .
    PIRi S50708.
    RefSeqi NP_012316.1. NM_001181652.1.

    3D structure databases

    ProteinModelPortali P40885.
    SMRi P40885. Positions 64-526.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 33562. 26 interactions.
    DIPi DIP-4609N.
    IntActi P40885. 1 interaction.
    MINTi MINT-479522.
    STRINGi 4932.YJL219W.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblFungii YJL219W ; YJL219W ; YJL219W .
    GeneIDi 853236.
    KEGGi sce:YJL219W.

    Organism-specific databases

    CYGDi YJL219w.
    SGDi S000003755. HXT9.

    Phylogenomic databases

    GeneTreei ENSGT00720000108754.
    HOGENOMi HOG000202870.
    KOi K08139.
    OMAi LRIVISM.
    OrthoDBi EOG73JM4H.

    Enzyme and pathway databases

    BioCyci YEAST:G3O-31643-MONOMER.

    Miscellaneous databases

    NextBioi 973458.

    Gene expression databases

    Genevestigatori P40885.

    Family and domain databases

    InterProi IPR020846. MFS_dom.
    IPR016196. MFS_dom_general_subst_transpt.
    IPR005828. Sub_transporter.
    IPR003663. Sugar/inositol_transpt.
    IPR005829. Sugar_transporter_CS.
    [Graphical view ]
    Pfami PF00083. Sugar_tr. 1 hit.
    [Graphical view ]
    PRINTSi PR00171. SUGRTRNSPORT.
    SUPFAMi SSF103473. SSF103473. 1 hit.
    TIGRFAMsi TIGR00879. SP. 1 hit.
    PROSITEi PS50850. MFS. 1 hit.
    PS00216. SUGAR_TRANSPORT_1. 1 hit.
    PS00217. SUGAR_TRANSPORT_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X."
      Vandenbol M., Durand P., Bolle P.-A., Dion C., Portetelle D., Hilger F.
      Yeast 10:1657-1662(1994) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    2. "Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
      Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K.
      , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
      EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 204508 / S288c.
    3. Cited for: GENOME REANNOTATION.
      Strain: ATCC 204508 / S288c.
    4. "A global topology map of the Saccharomyces cerevisiae membrane proteome."
      Kim H., Melen K., Oesterberg M., von Heijne G.
      Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
      Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
      Strain: ATCC 208353 / W303-1A.

    Entry informationi

    Entry nameiHXT9_YEAST
    AccessioniPrimary (citable) accession number: P40885
    Secondary accession number(s): D6VVX7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 1, 1995
    Last sequence update: February 1, 1995
    Last modified: October 1, 2014
    This is version 110 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families
    2. Yeast
      Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD
    3. Yeast chromosome X
      Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

    External Data

    Dasty 3