Hexose transporter HXT9 - Saccharomyces cerevisiae (Baker's yeast)

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Reviewed, UniProtKB/Swiss-Prot P40885 (HXT9_YEAST)

Last modified November 24, 2009. Version 73. History...

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Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein names

Recommended name:
Hexose transporter HXT9

Gene names

Name:	HXT9
Ordered Locus Names:	YJL219W
ORF Names:	J0222, HRC567

Organism

Saccharomyces cerevisiae (Baker's yeast) [Complete proteome]

Taxonomic identifier

4932 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Saccharomyces

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Protein attributes

Sequence length	567 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

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General annotation (Comments)

Function	Probable glucose transporter.
Subcellular location	Membrane; Multi-pass membrane protein.
Sequence similarities	Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

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Ontologies

Keywords
Biological process	Sugar transport Transport
Cellular component	Membrane
Domain	Repeat Transmembrane
PTM	Glycoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	hexose transport Inferred from genetic interaction. Source: SGD transmembrane transport Inferred from electronic annotation. Source: InterPro
Cellular component	integral to membrane Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	fructose transmembrane transporter activity Inferred from genetic interaction. Source: SGD galactose transmembrane transporter activity Inferred from genetic interaction. Source: SGD glucose transmembrane transporter activity Inferred from genetic interaction. Source: SGD mannose transmembrane transporter activity Inferred from genetic interaction. Source: SGD
Complete GO annotation...

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Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 567

567

Hexose transporter HXT9

PRO_0000050399

Regions

Topological domain

1 – 56

Cytoplasmic Potential

Transmembrane

57 – 77

1 Potential

Topological domain

78 – 112

Extracellular Potential

Transmembrane

113 – 133

2 Potential

Topological domain

134 – 139

Cytoplasmic Potential

Transmembrane

140 – 160

3 Potential

Topological domain

161 – 170

Extracellular Potential

Transmembrane

171 – 191

4 Potential

Topological domain

192 – 197

Cytoplasmic Potential

Transmembrane

198 – 218

5 Potential

Topological domain

219 – 232

Extracellular Potential

Transmembrane

233 – 253

6 Potential

Topological domain

254 – 336

Cytoplasmic Potential

Transmembrane

337 – 353

7 Potential

Topological domain

354 – 359

Extracellular Potential

Transmembrane

360 – 377

8 Potential

Topological domain

378 – 384

Cytoplasmic Potential

Transmembrane

385 – 405

9 Potential

Topological domain

406 – 429

Extracellular Potential

Transmembrane

430 – 450

10 Potential

Topological domain

451 – 467

Cytoplasmic Potential

Transmembrane

468 – 488

11 Potential

Topological domain

489

Extracellular Potential

Transmembrane

490 – 510

12 Potential

Topological domain

511 – 567

Cytoplasmic Potential

Amino acid modifications

Glycosylation

N-linked (GlcNAc...) Potential

Glycosylation

227

N-linked (GlcNAc...) Potential

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Sequences

Sequence

Length

Mass (Da)

Tools

P40885-1 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 2CF4C8617D9B2701
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FASTA

567

62,858

        10         20         30         40         50         60 
MSGVNNTSAN DLSTTESNSN SVANAPSVKT EHNDSKNSLN LDATEPPIDL PQKPLSAYTT 

        70         80         90        100        110        120 
VAILCLMIAF GGFIFGWDTG TISGFVNLSD FIRRFGQKND KGTYYLSKVR MGLIVSIFNI 

       130        140        150        160        170        180 
GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI NKWYQYFIGR IISGLGVGGI 

       190        200        210        220        230        240 
AVLSPMLISE VAPKQIRGTL VQLYQLMCTM GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA 

       250        260        270        280        290        300 
WTTFMVSGMM FVPESPRYLI EVGKDEEAKR SLSKSNKVSV DDPALLAEYD TIKAGIELEK 

       310        320        330        340        350        360 
LAGNASWSEL LSTKTKVFQR VLMGVMIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI 

       370        380        390        400        410        420 
IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP QGSSHQDITS 

       430        440        450        460        470        480 
QGAGNCMIVF TMFFIFSFAT TWAGGCYVIV SETFPLRVKS RGMAIATAAN WMWGFLISFF 

       490        500        510        520        530        540 
TPFITGAINF YYGYVFLGCL VFAYFYVFFF VPETKGLTLE EVNTMWLEGV PAWKSASWVP 

       550        560 
PERRTADYDA DAIDHDDRPI YKRFFSS

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References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X." Vandenbol M., Durand P., Bolle P.-A., Dion C., Portetelle D., Hilger F. Yeast 10:1657-1662(1994) [PubMed: 7725802] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[2]	"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X." Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. Karpfinger-Hartl L. EMBO J. 15:2031-2049(1996) [PubMed: 8641269] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 204508 / S288c.
[3]	"A global topology map of the Saccharomyces cerevisiae membrane proteome." Kim H., Melen K., Oesterberg M., von Heijne G. Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed: 16847258] [Abstract] Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
+	Additional computationally mapped references.

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Cross-references

Sequence databases
	Z34098 Genomic DNA. Translation: CAA83991.1. Z49494 Genomic DNA. Translation: CAA89516.1.
PIR	S50708.
RefSeq	NP_012316.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
DIP	DIP:4609N.
IntAct	P40885. 1 interaction.
STRING	P40885.
Genome annotation databases
Ensembl	YJL219W; YJL219W; YJL219W; Saccharomyces cerevisiae. [Genome view]
GeneID	853236.
KEGG	sce:YJL219W.
NMPDR	fig\|4932.3.peg.3279.
Organism-specific databases
CYGD	YJL219w.
SGD	S000003755. HXT9.
Phylogenomic databases
HOGENOM	P40885.
OMA	NNTSAND
OrthoDB	EOG95HTDF
Gene expression databases
ArrayExpress	P40885.
Genevestigator	P40885.
GermOnline	YJL219W. Saccharomyces cerevisiae.
Family and domain databases
InterPro	IPR016196. MFS_general_subst_transpt. IPR005828. Sub_transporter. IPR003663. Sugar/inositol_transpt. IPR005829. Sugar_transporter_CS. [Graphical view]
Pfam	PF00083. Sugar_tr. 1 hit. [Graphical view]
PRINTS	PR00171. SUGRTRNSPORT.
TIGRFAMs	TIGR00879. SP. 1 hit.
PROSITE	PS50850. MFS. 1 hit. PS00216. SUGAR_TRANSPORT_1. 1 hit. PS00217. SUGAR_TRANSPORT_2. 1 hit. [Graphical view]
ProtoNet	Search...
Other Resources
NextBio	973458.

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Entry information

Entry name

HXT9_YEAST

Accession

Primary (citable) accession number: P40885

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	February 1, 1995
Last modified:	November 24, 2009
This is version 73 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Names and origin

Protein attributes

General annotation (Comments)

Ontologies

Sequence annotation (Features)

Molecule processing

Regions

Amino acid modifications

Sequences

References

Cross-references

Sequence databases

3D structure databases

Protein-protein interaction databases

Genome annotation databases

Organism-specific databases

Phylogenomic databases

Gene expression databases

Family and domain databases

Other Resources

Entry information

Relevant documents