Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

P40885 (HXT9_YEAST) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 108. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Hexose transporter HXT9
Gene names
Name:HXT9
Ordered Locus Names:YJL219W
ORF Names:HRC567, J0222
OrganismSaccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) [Reference proteome]
Taxonomic identifier559292 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

Protein attributes

Sequence length567 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Probable glucose transporter.

Subcellular location

Membrane; Multi-pass membrane protein.

Sequence similarities

Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. [View classification]

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 567567Hexose transporter HXT9
PRO_0000050399

Regions

Topological domain1 – 5656Cytoplasmic Potential
Transmembrane57 – 7721Helical; Name=1; Potential
Topological domain78 – 11235Extracellular Potential
Transmembrane113 – 13321Helical; Name=2; Potential
Topological domain134 – 1396Cytoplasmic Potential
Transmembrane140 – 16021Helical; Name=3; Potential
Topological domain161 – 17010Extracellular Potential
Transmembrane171 – 19121Helical; Name=4; Potential
Topological domain192 – 1976Cytoplasmic Potential
Transmembrane198 – 21821Helical; Name=5; Potential
Topological domain219 – 23214Extracellular Potential
Transmembrane233 – 25321Helical; Name=6; Potential
Topological domain254 – 33683Cytoplasmic Potential
Transmembrane337 – 35317Helical; Name=7; Potential
Topological domain354 – 3596Extracellular Potential
Transmembrane360 – 37718Helical; Name=8; Potential
Topological domain378 – 3847Cytoplasmic Potential
Transmembrane385 – 40521Helical; Name=9; Potential
Topological domain406 – 42924Extracellular Potential
Transmembrane430 – 45021Helical; Name=10; Potential
Topological domain451 – 46717Cytoplasmic Potential
Transmembrane468 – 48821Helical; Name=11; Potential
Topological domain4891Extracellular Potential
Transmembrane490 – 51021Helical; Name=12; Potential
Topological domain511 – 56757Cytoplasmic Potential

Amino acid modifications

Glycosylation871N-linked (GlcNAc...) Potential
Glycosylation2271N-linked (GlcNAc...) Potential

Sequences

Sequence LengthMass (Da)Tools
P40885 [UniParc].

Last modified February 1, 1995. Version 1.
Checksum: 2CF4C8617D9B2701

FASTA56762,858
        10         20         30         40         50         60 
MSGVNNTSAN DLSTTESNSN SVANAPSVKT EHNDSKNSLN LDATEPPIDL PQKPLSAYTT 

        70         80         90        100        110        120 
VAILCLMIAF GGFIFGWDTG TISGFVNLSD FIRRFGQKND KGTYYLSKVR MGLIVSIFNI 

       130        140        150        160        170        180 
GCAIGGIVLS KVGDIYGRRI GLITVTAIYV VGILIQITSI NKWYQYFIGR IISGLGVGGI 

       190        200        210        220        230        240 
AVLSPMLISE VAPKQIRGTL VQLYQLMCTM GIFLGYCTNY GTKNYHNATQ WRVGLGLCFA 

       250        260        270        280        290        300 
WTTFMVSGMM FVPESPRYLI EVGKDEEAKR SLSKSNKVSV DDPALLAEYD TIKAGIELEK 

       310        320        330        340        350        360 
LAGNASWSEL LSTKTKVFQR VLMGVMIQSL QQLTGDNYFF YYGTTIFKSV GLKDSFQTSI 

       370        380        390        400        410        420 
IIGVVNFFSS FIAVYTIERF GRRTCLLWGA ASMLCCFAVF ASVGVTKLWP QGSSHQDITS 

       430        440        450        460        470        480 
QGAGNCMIVF TMFFIFSFAT TWAGGCYVIV SETFPLRVKS RGMAIATAAN WMWGFLISFF 

       490        500        510        520        530        540 
TPFITGAINF YYGYVFLGCL VFAYFYVFFF VPETKGLTLE EVNTMWLEGV PAWKSASWVP 

       550        560 
PERRTADYDA DAIDHDDRPI YKRFFSS 

« Hide

References

« Hide 'large scale' references
[1]"Sequence analysis of a 40.2 kb DNA fragment located near the left telomere of yeast chromosome X."
Vandenbol M., Durand P., Bolle P.-A., Dion C., Portetelle D., Hilger F.
Yeast 10:1657-1662(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[2]"Complete nucleotide sequence of Saccharomyces cerevisiae chromosome X."
Galibert F., Alexandraki D., Baur A., Boles E., Chalwatzis N., Chuat J.-C., Coster F., Cziepluch C., de Haan M., Domdey H., Durand P., Entian K.-D., Gatius M., Goffeau A., Grivell L.A., Hennemann A., Herbert C.J., Heumann K. expand/collapse author list , Hilger F., Hollenberg C.P., Huang M.-E., Jacq C., Jauniaux J.-C., Katsoulou C., Kirchrath L., Kleine K., Kordes E., Koetter P., Liebl S., Louis E.J., Manus V., Mewes H.-W., Miosga T., Obermaier B., Perea J., Pohl T.M., Portetelle D., Pujol A., Purnelle B., Ramezani Rad M., Rasmussen S.W., Rose M., Rossau R., Schaaff-Gerstenschlaeger I., Smits P.H.M., Scarcez T., Soriano N., To Van D., Tzermia M., Van Broekhoven A., Vandenbol M., Wedler H., von Wettstein D., Wambutt R., Zagulski M., Zollner A., Karpfinger-Hartl L.
EMBO J. 15:2031-2049(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 204508 / S288c.
[3]Saccharomyces Genome Database
Submitted (DEC-2009) to the EMBL/GenBank/DDBJ databases
Cited for: GENOME REANNOTATION.
Strain: ATCC 204508 / S288c.
[4]"A global topology map of the Saccharomyces cerevisiae membrane proteome."
Kim H., Melen K., Oesterberg M., von Heijne G.
Proc. Natl. Acad. Sci. U.S.A. 103:11142-11147(2006) [PubMed] [Europe PMC] [Abstract]
Cited for: TOPOLOGY [LARGE SCALE ANALYSIS].
Strain: ATCC 208353 / W303-1A.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z34098 Genomic DNA. Translation: CAA83991.1.
Z49494 Genomic DNA. Translation: CAA89516.1.
BK006943 Genomic DNA. Translation: DAA08593.1.
PIRS50708.
RefSeqNP_012316.1. NM_001181652.1.

3D structure databases

ProteinModelPortalP40885.
SMRP40885. Positions 64-526.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

BioGrid33562. 26 interactions.
DIPDIP-4609N.
IntActP40885. 1 interaction.
MINTMINT-479522.
STRING4932.YJL219W.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblFungiYJL219W; YJL219W; YJL219W.
GeneID853236.
KEGGsce:YJL219W.

Organism-specific databases

CYGDYJL219w.
SGDS000003755. HXT9.

Phylogenomic databases

GeneTreeENSGT00720000108754.
HOGENOMHOG000202870.
KOK08139.
OrthoDBEOG73JM4H.

Enzyme and pathway databases

BioCycYEAST:G3O-31643-MONOMER.

Gene expression databases

GenevestigatorP40885.

Family and domain databases

InterProIPR020846. MFS_dom.
IPR016196. MFS_dom_general_subst_transpt.
IPR005828. Sub_transporter.
IPR003663. Sugar/inositol_transpt.
IPR005829. Sugar_transporter_CS.
[Graphical view]
PfamPF00083. Sugar_tr. 1 hit.
[Graphical view]
PRINTSPR00171. SUGRTRNSPORT.
SUPFAMSSF103473. SSF103473. 1 hit.
TIGRFAMsTIGR00879. SP. 1 hit.
PROSITEPS50850. MFS. 1 hit.
PS00216. SUGAR_TRANSPORT_1. 1 hit.
PS00217. SUGAR_TRANSPORT_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

NextBio973458.

Entry information

Entry nameHXT9_YEAST
AccessionPrimary (citable) accession number: P40885
Secondary accession number(s): D6VVX7
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: April 16, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

Yeast chromosome X

Yeast (Saccharomyces cerevisiae) chromosome X: entries and gene names

Yeast

Yeast (Saccharomyces cerevisiae): entries, gene names and cross-references to SGD

SIMILARITY comments

Index of protein domains and families