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Protein

Regulatory protein PchR

Gene

pchR

Organism
Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Positive activator of the genes for pyochelin and ferripyochelin receptors.

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
DNA bindingi217 – 23620H-T-H motifPROSITE-ProRule annotationAdd
BLAST

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Activator

Keywords - Biological processi

Transcription, Transcription regulation

Keywords - Ligandi

DNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Regulatory protein PchR
Gene namesi
Name:pchR
Ordered Locus Names:PA4227
OrganismiPseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
Taxonomic identifieri208964 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPseudomonadalesPseudomonadaceaePseudomonas
Proteomesi
  • UP000002438 Componenti: Chromosome

Organism-specific databases

PseudoCAPiPA4227.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 296296Regulatory protein PchRPRO_0000194544Add
BLAST

Proteomic databases

PaxDbiP40883.

Expressioni

Inductioni

Expression is iron regulated.

Gene expression databases

CollecTFiEXPREG_00000aa0.

Interactioni

Protein-protein interaction databases

STRINGi208964.PA4227.

Structurei

3D structure databases

ProteinModelPortaliP40883.
SMRiP40883. Positions 219-296.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains 1 HTH araC/xylS-type DNA-binding domain.PROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG4105WPR. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000217265.
InParanoidiP40883.
KOiK12243.
OMAiAHEMLCA.
OrthoDBiEOG62G5KV.
PhylomeDBiP40883.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

P40883-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTITIIAPPQ ADAAAPAPGN RPGVAHIDPN MKLVTGTFCS ASEDWFEEPL
60 70 80 90 100
ERGLRLILVQ SGQLRCRIPG QPEHLIEGPS LCTIANDGDF TSAQIYGTDK
110 120 130 140 150
PLRYTIVQLG VEALDSRLGW LPEQLIRRPG GDPRIMSCPA PRAMQALASQ
160 170 180 190 200
IATCQMLGPT RDLYLGGKAL ELAALSAQFL SGEGRPVEEP RITCSEVERI
210 220 230 240 250
HAARDLLVGA LQEPPSLDTL ASRVGMNPRK LTAGFRKVFG ASVFGYLQEY
260 270 280 290
RLREAHRMLC DEEANVSTVA YRVGYSPAHF SIAFRKRYGI SPSEIR
Length:296
Mass (Da):32,339
Last modified:February 1, 1995 - v1
Checksum:i6EF141CF852D7D84
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11657 Genomic DNA. Translation: AAA25926.1.
AE004091 Genomic DNA. Translation: AAG07615.1.
PIRiA48496.
RefSeqiNP_252917.1. NC_002516.2.
WP_003106955.1. NZ_ASJY01000703.1.

Genome annotation databases

EnsemblBacteriaiAAG07615; AAG07615; PA4227.
GeneIDi880049.
KEGGipae:PA4227.
PATRICi19843144. VBIPseAer58763_4428.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L11657 Genomic DNA. Translation: AAA25926.1.
AE004091 Genomic DNA. Translation: AAG07615.1.
PIRiA48496.
RefSeqiNP_252917.1. NC_002516.2.
WP_003106955.1. NZ_ASJY01000703.1.

3D structure databases

ProteinModelPortaliP40883.
SMRiP40883. Positions 219-296.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi208964.PA4227.

Proteomic databases

PaxDbiP40883.

Protocols and materials databases

DNASUi880049.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAG07615; AAG07615; PA4227.
GeneIDi880049.
KEGGipae:PA4227.
PATRICi19843144. VBIPseAer58763_4428.

Organism-specific databases

PseudoCAPiPA4227.

Phylogenomic databases

eggNOGiENOG4105WPR. Bacteria.
COG2207. LUCA.
HOGENOMiHOG000217265.
InParanoidiP40883.
KOiK12243.
OMAiAHEMLCA.
OrthoDBiEOG62G5KV.
PhylomeDBiP40883.

Gene expression databases

CollecTFiEXPREG_00000aa0.

Family and domain databases

Gene3Di1.10.10.60. 2 hits.
InterProiIPR009057. Homeodomain-like.
IPR018060. HTH_AraC.
IPR018062. HTH_AraC-typ_CS.
[Graphical view]
PfamiPF12833. HTH_18. 1 hit.
[Graphical view]
SMARTiSM00342. HTH_ARAC. 1 hit.
[Graphical view]
SUPFAMiSSF46689. SSF46689. 2 hits.
PROSITEiPS00041. HTH_ARAC_FAMILY_1. 1 hit.
PS01124. HTH_ARAC_FAMILY_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Cloning and sequence analysis of a gene (pchR) encoding an AraC family activator of pyochelin and ferripyochelin receptor synthesis in Pseudomonas aeruginosa."
    Heinrichs D.E., Poole K.
    J. Bacteriol. 175:5882-5889(1993) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228.

Entry informationi

Entry nameiPCHR_PSEAE
AccessioniPrimary (citable) accession number: P40883
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: February 1, 1995
Last modified: February 17, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.