Reviewed, UniProtKB/Swiss-Prot P40783 (QOR_SALTY)

Names and origin

Protein names

Recommended name:
    Quinone oxidoreductase
    EC=1.6.5.5
Alternative name(s):
    NADPH:quinone reductase
    Zeta-crystallin homolog protein

Gene names

Name:	qor
Ordered Locus Names:	STM4245

Organism

Salmonella typhimurium [Complete proteome] [HAMAP]

Taxonomic identifier

602 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacteriales › Enterobacteriaceae › Salmonella

Protein attributes

Sequence length	327 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	NADPH + 2 quinone = NADP(+) + 2 semiquinone.
Subunit structure	Homodimer By similarity.
Sequence similarities	Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Ontologies

Keywords
Ligand	NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: InterPro
Molecular function	NADPH:quinone reductase activity Inferred from electronic annotation. Source: EC zinc ion binding Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 327	327	Quinone oxidoreductase		PRO_0000160902
Experimental info
	Sequence conflict	92	1	L → V in J03390. Ref.2
	Sequence conflict	148	1	A → R in J03390. Ref.2

Sequences

	Sequence		Length	Mass (Da)
	P40783-1 [UniParc]. Last modified December 13, 2001. Version 2. Checksum: 602F4CB6E6A805F1	FASTA	327	35,151
	10 20 30 40 50 60 MATRIEFHKH GGPEVLQTVE FTPAEPAEHE IQVENKAIGI NFIDTYIRSG LYPPPSLPAG 70 80 90 100 110 120 LGTEAAGVVS KVGNGVEHIR VGDRVVYAQS TLGAYSSVHN VTADKAAILP DAISFEQAAA 130 140 150 160 170 180 SFLKGLTVFY LLRKTYEVKP DEPFLFHAAA GGVGLIACQW AKALGAKLIG TVGSAQKAQR 190 200 210 220 230 240 ALDAGAWQVI NYREESIVER VKEITGGKKV RVVYDSVGKD TWEASLDCLQ RRGLMVSFGN 250 260 270 280 290 300 ASGPVTGVNL GILNQKGSLY ATRPSLQGYI TTREELTEAS NELFSLIASG VIKVDVAENQ 310 320 RYALKDARRA HEVLESRATQ GSSLLIP

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2." McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E. , Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K. Nature 413:852-856(2001) [PubMed: 11677609] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: LT2 / SGSC1412 / ATCC 700720.
[2]	"Sequence of the dnaB gene of Salmonella typhimurium." Wong A., Kean L., Maurer R. J. Bacteriol. 170:2668-2675(1988) [PubMed: 2836367] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 1-168.

Cross-references

Sequence databases
EMBLGenBankDDBJ	AE008898 Genomic DNA. Translation: AAL23069.1. J03390 Genomic DNA. No translation available.
RefSeq	NP_463110.1.
3D structure databases
HSSP	HSSP built from PDB template 1QOR based on UniProtKB P28304.
SMR	P40783. Positions 2-327.
ModBase	Search...
Genome annotation databases
GeneID	1255771.
GenomeReviews	Gene locus STM4245 in contig AE006468_GR.
KEGG	stm:STM4245.
NMPDR	fig|99287.1.peg.4083.
Organism-specific databases
StyGene	qor. SG10511.
CMR	Search...
Phylogenomic databases
HOGENOM	P40783.
Enzyme and pathway databases
BioCyc	STYP99287:STM4245-MON.
Family and domain databases
InterPro	IPR013154. AlcDHase_GroES-like. IPR002085. AlcDHase_SF_Zn. IPR013149. AlcDHase_Zn-bd. IPR016040. NAD(P)-bd. IPR002364. Quin_OxRdtase/zeta-crystal_CS. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHER	PTHR11695. ADH_Sf_Zn. 1 hit.
Pfam	PF08240. ADH_N. 1 hit. PF00107. ADH_zinc_N. 1 hit. [Graphical view]
PROSITE	PS01162. QOR_ZETA_CRYSTAL. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

QOR_SALTY

Accession

Primary (citable) accession number: P40783

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 1995
Last sequence update:	December 13, 2001
Last modified:	November 25, 2008
This is version 54 of the entry and version 2 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)