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Reviewed, UniProtKB/Swiss-Prot P40740 (BGL1_BACSU)

Last modified November 25, 2008. Version 63. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Beta-glucosidase
    EC=3.2.1.21
Alternative name(s):
    Gentiobiase
    Cellobiase
    Beta-D-glucoside glucohydrolase
    Amygdalase
Gene names
Name: bglH
Ordered Locus Names: BSU39260
ORF Names: N17D
OrganismBacillus subtilis [Complete proteome] [HAMAP]
Taxonomic identifier1423 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus

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Protein attributes

Sequence length469 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

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General annotation (Comments)

Catalytic activity

Hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose.

Sequence similarities

Belongs to the glycosyl hydrolase 1 family.

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Ontologies

Keywords

   Biological processCarbohydrate metabolism
Cellulose degradation
Polysaccharide degradation
   Molecular functionGlycosidase
Hydrolase
   Technical termComplete proteome

Gene Ontology (GO)

   Biological processcellulose catabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionbeta-glucosidase activity

Inferred from electronic annotation. Source: EC

cation binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 469469Beta-glucosidase
PRO_0000063873

Sites

Active site1751Proton donor Potential
Active site3681Nucleophile By similarity

Experimental info

Sequence conflict4021A → R in CAA84287. Ref.1

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Sequences

Sequence LengthMass (Da)Tools
P40740-1 [UniParc].

Last modified May 30, 2000. Version 2.
Checksum: 4C0CA25F964C1CC1

FASTA46953,289
        10         20         30         40         50         60 
MSSNEKRFPE GFLWGGAVAA NQVEGAYNEG GKGLSTADVS PNGIMSPFDE SMTSLNLYHN 

        70         80         90        100        110        120 
GIDFYHRYKE DIALFAEMGF KAFRTSIAWT RIFPNGDEEE PNEEGLRFYD DLFDELLKHH 

       130        140        150        160        170        180 
IEPVVTISHY EMPLGLVKNY GGWKNRKVIE FYERYAKTVF KRYQHKVKYW MTFNEINVVL 

       190        200        210        220        230        240 
HAPFTGGGLV FEEGENKLNA MYQAAHHQFV ASALAVKAGH DIIPDSKIGC MIAATTTYPM 

       250        260        270        280        290        300 
TSKPEDVFAA MENERKTLFF SDVQARGAYP GYMKRYLAEN NIEIEMAEGD EELLKEHTVD 

       310        320        330        340        350        360 
YIGFSYYMSM AASTDPEELA KSGGNLLGGV KNPYLKSSEW GWQIDPKGLR ITLNTLYDRY 

       370        380        390        400        410        420 
QKPLFIVENG LGAVDKVEED GTIQDDYRIN YLRDHLIEAR EAIADGVELI GYTSWGPIDL 

       430        440        450        460 
VSASTAEMKK RYGFIYVDRD NEGNGTFNRI KKKSFNWYQQ VIATNGESL

« Hide

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References

« Hide 'large scale' references
[1]"New beta-glucoside (bgl) genes in Bacillus subtilis: the bglP gene product has both transport and regulatory functions similar to those of BglF, its Escherichia coli homolog."
Le Coq D., Lindner C., Krueger S., Steinmetz M., Stuelke J.
J. Bacteriol. 177:1527-1535(1995) [PubMed: 7883710] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / Marburg.
[2]"Cloning and sequencing of a 29 kb region of the Bacillus subtilis genome containing the hut and wapA loci."
Yoshida K., Sano H., Seki S., Oda M., Fujimura M., Fujita Y.
Microbiology 141:337-343(1995) [PubMed: 7704263] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 168 / BGSC1A1.
[3]"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis."
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V. expand/collapse author list , Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.
Nature 390:249-256(1997) [PubMed: 9384377] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 168.

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Cross-references

Sequence databases

Z34526 Genomic DNA. Translation: CAA84287.1.
D31856 Genomic DNA. Translation: BAA06653.1.
D29985 Genomic DNA. Translation: BAA06257.1.
Z99124 Genomic DNA. Translation: CAB15962.2.
PIRH69593.
RefSeqNP_391805.2.

3D structure databases

HSSPHSSP built from PDB template 1PBG based on UniProtKB P11546.
ModBaseSearch...

Genome annotation databases

GeneID937512.
GenomeReviewsGene locus BSU39260 in contig AL009126_GR.
KEGGbsu:BSU39260.
NMPDRfig|224308.1.peg.3931.

Organism-specific databases

SubtiListBG10935. bglH. [Micado]
CMRSearch...

Phylogenomic databases

HOGENOMP40740.

Enzyme and pathway databases

BioCycBSUB224308:BSU3922-MON.

Family and domain databases

InterProIPR001360. Glyco_hydro_1.
IPR013781. Glyco_hydro_sub_cat.
[Graphical view]
Gene3DG3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit.
PANTHERPTHR10353. Glyco_hydro_1. 1 hit.
PfamPF00232. Glyco_hydro_1. 1 hit.
[Graphical view]
PRINTSPR00131. GLHYDRLASE1.
PROSITEPS00572. GLYCOSYL_HYDROL_F1_1. 1 hit.
PS00653. GLYCOSYL_HYDROL_F1_2. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameBGL1_BACSU
AccessionPrimary (citable) accession number: P40740
Secondary accession number(s): O32287
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 1995
Last sequence update: May 30, 2000
Last modified: November 25, 2008
This is version 63 of the entry and version 2 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

Bacillus subtilis

Bacillus subtilis (strain 168): entries, gene names and cross-references to SubtiList

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents